CD334 / FGFR4 antibody

Principal name

CD334 / FGFR4 antibody

Alternative names for CD334 / FGFR4 antibody

FGFR-4, JTK2, TKF, Fibroblast growth factor receptor 4

SwissProt ID

P22455 (Human), Q03142 (Mouse), Q498D6 (Rat)

Gene ID

2264 (FGFR4)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit, Mouse

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Flow Cytometry (F)

Background of CD334 / FGFR4 antibody

Fibroblast growth factors (FGFs) comprise a family of at least eighteen structurally related proteins that are involved in a multitude of physiological and pathological cellular processes, including cell growth, differentiation, angiogenesis, wound healing and tumorigenesis. The biological activities of the FGFs are mediated by a family of type I transmembrane tyrosine kinases which undergo dimerization and autophosphorylation after ligand binding. Four distinct genes encoding closely related FGF receptors, FGFR-1 to -4, are known. All four genes for FGF-receptors encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid-box region containing a run of acidic residues between the IgI and IgII domains, a transmembrane domain and the split tyrosine-kinase domain. Multiple forms of FGFR-1 to -3 are generated by alternative splicing of the mRNAs. A frequent splicing event involving FGFR-1 and -2 results in receptors containing all three Ig domains, referred to as the alpha isoform, or only IgII and IgIII, referred to as the beta isoform. Only the alpha isoform has been identified for FGFR-3 and FGFR-4. Additional splicing events for FGFR-1 to -3, involving the C-terminal half of the IgIII domain encoded by two mutually exclusive alternative exons, generate FGF receptors with alternative IgIII domains (IIIb and IIIc). A IIIa isoform which is a secreted FGF binding protein containing only the N-terminal half of the IgIII domain plus some intron sequences has also been reported for FGFR-1. Mutations in FGFR-1 to -3 have been found in patients with birth defects involving craniosynostosis. The complex patterns of expression of these receptors as well as the specificity of their interactions with the various FGF ligand family members are under investigation.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CD334 / FGFR4 (N-term) antibody

FGFR4 Antibody (E39) (Cat. #TA324961) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the FGFR4 antibody detected the FGFR4 protein (arrow). Rabbit Ig Purified Hu P, WB
0.4 ml / €325.00
  OriGene Technologies, Inc.

CD334 / FGFR4 antibody

Immunohistochemical staining of paraffin-embedded Human pancreas tissue using anti-FGFR4 Rabbit Polyclonal antibody. (TA590109) Rabbit IgG Purified Hu E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CD334 / FGFR4 antibody

Western blot analysis of anti-FGFR4 Monoclonal Antibody (Cat.#TA302088) by FGFR4 recombinant protein(Fragment 42KD). FGFR4 protein (arrow) was detected using the ascites Mab. Mouse IgG1 53CT32.19.3 Ascites Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CD334 / FGFR4 antibody

Western blot analysis of anti-FGFR4 Monoclonal Antibody (Cat.TA302089) by FGFR4 recombinant protein(Fragment 42KD). FGFR4 protein (arrow) was detected using the purified Mab. Mouse IgG1 53CT32.19.3 Purified Hu P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CD334 / FGFR4 antibody

Predicted band size: 88 kDa . Positive control: Rat liver and Rat brain tissue lysate. Recommended dilution: 1/ 500-1000. (Gel: 8%SDS-PAGE Lane1,2: Rat liver and Rat brain tissue lysate Lysates: 30 ug per lane Primary antibody: 1/500 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute) Rabbit IgG Purified Hu, Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CD334 / FGFR4 antibody

Immunohistochemical analysis of paraffin-embedded human liver tissues using FGFR4 antibody Cat.-No AM06181SU-N Mouse IgG1 4H2B10B2 Ascites Hu P, WB
0.1 ml / €400.00
  Acris Antibodies GmbH

CD334 / FGFR4 antibody

Confocal Immunofluorescence analysis of methanol-fixed HEK293 cells trasfected with FGFR4-hIgGFc using FGFR4 antibody Cat.-No AM06322SU-N (green), showing membrane localization. Blue: DRAQ5 fluorescent DNA dye. Mouse IgG1 7H1 Ascites Hu E, ICC/IF, WB
0.1 ml / €400.00
  Acris Antibodies GmbH

CD334 / FGFR4 antibody

Formalin-Fixed, Paraffin-Embedded Human Liver stained with FGFR4 antibody Cat.-No. AM20516PU-N followed by biotinylated anti-mouse IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen. Mouse IgG1 4H2B10B2 Ascites Hu C, E, P, WB
50 µl / €470.00
  Acris Antibodies GmbH

CD334 / FGFR4 antibody

Western blot analysis of FGFR4 (arrow) using rabbit polyclonal FGFR4 Antibody.293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the FGFR4 gene (Lane 2) Rabbit Ig Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CD334 / FGFR4 pTyr642 antibody

Western blot analysis of extracts from JK cells (Lane 2), using FGFR4 (Phospho-Tyr642) Antibody AP55850PU-N. The lane on the left is treated with antigen-specific peptide. Rabbit Aff - Purified Hu, Ms, Rt WB
0.1 ml / €340.00
  Acris Antibodies GmbH

CD334 / FGFR4 pTyr642 antibody

Western blot analysis of extracts from JK cells (Lane 2), using FGFR4 (Phospho-Tyr642) Antibody AP55850PU-N. The lane on the left is treated with antigen-specific peptide. Rabbit Aff - Purified Hu, Ms, Rt WB
50 µl / €270.00
  Acris Antibodies GmbH

CD334 / FGFR4 antibody

Proximity Ligation Analysis (PLA) of protein-protein interactions between FGF1 and FGFR4 HeLa cells were stained with anti-FGF1 rabbit purified polyclonal 1:1200 and anti-FGFR4 mouse monoclonal antibody 1:50. Signals were detected by Duolink® 30 Detection Kit 613(red), and nuclei were counterstained with DAPI (blue). Each red dot represents the detection of protein-protein interaction complex. Mouse IgG2a 1E2 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

CD334 / FGFR4 antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with FGFR4 polyclonal antibody ( Cat # PAB3044 ) , which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. HC = hepatocarcinoma. Rabbit Hu E, P, WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

CD334 / FGFR4 (transcript variant 2)

CD334 / FGFR4 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

CD334 / FGFR4 (C-term DDK/His tag, transcript variant 1)

CD334 / FGFR4 Human > 80 %
Preparation: .
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

CD334 / FGFR4 (Fc Chimera)

CD334 / FGFR4 Human Purified > 90 % by SDS-PAGE and visualised by silver stain. Insect cells
10 µg / €170.00
  Acris Antibodies GmbH

CD334 / FGFR4 (Fc Chimera)

CD334 / FGFR4 Human Purified > 90 % by SDS-PAGE and visualised by silver stain. Insect cells
50 µg / €290.00
  Acris Antibodies GmbH

CD334 / FGFR4

CD334 / FGFR4 Human
10 µg / €540.00
  Abnova Taiwan Corp.

CD334 / FGFR4

CD334 / FGFR4 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

CD334 / FGFR4

CD334 / FGFR4 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Items 1 to 20 of 29 total

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