CD338 / ABCG2 / BCRP1 antibody

Principal name

CD338 / ABCG2 / BCRP1 antibody

Alternative names for CD338 / ABCG2 / BCRP1 antibody

Breast cancer resistance protein 1, ABCP, MXR, Mitoxantrone resistance-associated protein, Placenta-specific ATP-binding cassette transporter, ATP-binding cassette sub-family G member 2

SwissProt ID

Q7TMS5 (Mouse), Q80W57 (Rat), Q9UNQ0 (Human)

Gene ID

9429 (ABCG2), 26357 (Abcg2)

Available reactivities

Can (Canine), Hu (Human), Ms (Mouse), Bov (Bovine), Chk (Chicken), Por (Porcine), Rt (Rat), Ze (Zebrafish), African clawed frog, Mky (Monkey), Xen (Xenopus), Prim (Primate)

Available hosts

Rabbit, Mouse, Rat

Available applications

Enzyme Immunoassay (E), Paraffin Sections (P), Western blot / Immunoblot (WB), Dot blot (Dot), Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF), ELISA (detection) (E(detection)), Flow Cytometry (F)

Background of CD338 / ABCG2 / BCRP1 antibody

ABCG2 is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue.The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue.

General readings

1. Doyle, L.A., et al., A multidrug resistance transporter from human MCF-7 breast cancer cells. Proc. Natl. Acad. Sci. USA, 95, 15665-15670 (1998).
2. Scheffer, G.L., et al., Breast Cancer Resistance Protein is localized at the plasma membrane in mitoxantrone and topotecan resistant cell lines. Cancer Res., 60, 2589-2593 (2000).
3. Maliepaard, M., et al., Subcellular localization and
distribution of the breast cancer resistance protein transporter in normal human tissues. Cancer Res., 61, 3458-3464 (2001).

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CD338 / ABCG2 / BCRP1 antibody

Immunohistochemical analysis of paraffin-embedded bladder cancer tissues (left) and skeletal muscle tissues (right) using ABCG2 mouse mAb with DAB staining. Mouse IgG1 3G8 Ascites Hu, Mky, Ms E, ICC/IF, P, WB
0.1 ml / €430.00
  Acris Antibodies GmbH

CD338 / ABCG2 / BCRP1 antibody

CD338 / ABCG2 / BCRP1 Mouse 5D3 Purified Hu F
25 µg / €120.00
  OriGene Technologies, Inc.

CD338 / ABCG2 / BCRP1 antibody

Predicted band size: 72kDa. Positive control: HepG2 cell lysate. Recommended dilution: 1/1000-5000. (Gel: 10%SDS-PAGE Lysate: 20 ug Primary antibody: 1/1000 dilution Secondary antibody: Donkey anti Rabbit IgG - H&L (HRP) at 1/3000 dilution Exposure time: 10 seconds) Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CD338 / ABCG2 / BCRP1 antibody

Predicted band size: 72 kDa . Positive control: HL-60 cells lysate. Recommended dilution: 1/ 500-1000. (Gel: 8%SDS-PAGE Lane1,2,3,4: Rat brain,Mouse brain,C6 and mouse heart lysate Lysates: 30 ug per lane Primary antibody: 1/500 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute) Rabbit IgG Purified Hu, Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CD338 / ABCG2 / BCRP1 antibody

Predicted band size: 72kDa. Positive control: HepG2 cell lysate. Recommended dilution: 1/1000-5000. (Gel: 10%SDS-PAGE Lysate: 20 ug Primary antibody: 1/1000 dilution Secondary antibody: Donkey anti Rabbit IgG - H&L (HRP) at 1/3000 dilution Exposure time: 10 seconds) Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CD338 / ABCG2 / BCRP1 antibody

Western Blot: ABCG2 Antibody (3G8) [TA336921] - Analysis of ABCG2 expression in 1) human small intestine, 2) human placenta and 3) mouse placenta tissue extracts. Mouse IgG1 3G8 Purified Hu, Ms, Prim C, E, F, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CD338 / ABCG2 / BCRP1 antibody

Western blot analysis of extract from HL-60 cells using ABCG2(CD338) Antibody Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CD338 / ABCG2 / BCRP1 antibody

ELISA: ABCG2 Antibody Rabbit IgG Purified Hu E
0.1 mg / €325.00
  OriGene Technologies, Inc.

CD338 / ABCG2 / BCRP1 antibody

ELISA: ABCG2 Antibody Rabbit IgG Purified Hu E
0.1 mg / €325.00
  OriGene Technologies, Inc.

CD338 / ABCG2 / BCRP1 antibody

Immunofluorescence analysis of Hela cells using ABCG2 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin. Mouse IgG1 1H2 Ascites Hu, Mky, Ms E, ICC/IF, WB
0.1 ml / €430.00
  Acris Antibodies GmbH

CD338 / ABCG2 / BCRP1 antibody

CD338 / ABCG2 / BCRP1 Rat IgG2a BXP-53 Supernatant Hu, Ms C, ICC/IF, WB
1 ml / €420.00
  Acris Antibodies GmbH

CD338 / ABCG2 / BCRP1 antibody

CD338 / ABCG2 / BCRP1 Rat IgG1 BXP-9 Supernatant Hu, Ms C, ICC/IF, WB
1 ml / €420.00
  Acris Antibodies GmbH

CD338 / ABCG2 / BCRP1 antibody

CD338 / ABCG2 / BCRP1 Mouse IgG2a BXP-21 Supernatant Hu C, ICC/IF, P, WB
1 ml / €420.00
  Acris Antibodies GmbH

CD338 / ABCG2 / BCRP1 antibody

CD338 / ABCG2 / BCRP1 Mouse IgG1 BXP-34 Liquid Hu C, ICC/IF, WB
1 ml / €420.00
  Acris Antibodies GmbH

CD338 / ABCG2 / BCRP1 antibody

Immunohistochemistry (IHC) analyzes of ABCG2 antibody (Cat.-No.: AP20605PU-N) in paraffin-embedded human brain tissue. Rabbit Aff - Purified Hu WB
0.1 mg / €350.00
  Acris Antibodies GmbH

CD338 / ABCG2 / BCRP1 antibody

ABCG2 polyclonal antibody (A01), Lot # 051017JC01. Western Blot analysis of ABCG2 expression in Raw 264.7. Mouse Serum Hu, Ms E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

CD338 / ABCG2 / BCRP1 antibody

Western Blot analysis of ABCG2 expression in transfected 293T cell line (H00009429-T01) by ABCG2 MaxPab polyclonal antibody.

Lane 1: ABCG2 transfected lysate(72.05 KDa).
Lane 2: Non-transfected lysate. Mouse Purified Hu E(detection), F, WB
50 µg / €370.00
  Abnova Taiwan Corp.

CD338 / ABCG2 / BCRP1 antibody

Western Blot analysis of ABCG2 expression in transfected 293T cell line (H00009429-T01) by ABCG2 MaxPab polyclonal antibody.

Lane 1: ABCG2 transfected lysate(72.30 KDa).
Lane 2: Non-transfected lysate. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

CD338 / ABCG2 / BCRP1 antibody

CD338 / ABCG2 / BCRP1 Mouse IgG2a 1G1 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

CD338 / ABCG2 / BCRP1 antibody

CD338 / ABCG2 / BCRP1 Rat IgG1 BXP-9 Ms C, F, ICC/IF, WB
1 ml / €820.00
  Abnova Taiwan Corp.

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