CD36 antibody

Principal name

CD36 antibody

Alternative names for CD36 antibody

Glycoprotein IIIb, PAS IV, PAS-4, Thrombospondin receptor, GP3B, GP4, Platelet glycoprotein 4, Platelet glycoprotein IV, Platelet collagen receptor, Fatty acid translocase

SwissProt ID

P16671 (Human), P26201 (Bovin), Q07969 (Rat), Q08857 (Mouse)

Gene ID

948 (CD36), 12491 (Cd36)

Available reactivities

Hu (Human), Bov (Bovine), Mky (Monkey), Ms (Mouse), Rt (Rat), Hst (Hamster), Rb (Rabbit), Can (Canine), Por (Porcine)

Available hosts

Mouse, Rabbit, Rat

Available applications

Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF), Flow Cytometry (F), Western blot / Immunoblot (WB), Functional assay (FN), Paraffin Sections (P), Immunoprecipitation (IP), Enzyme Immunoassay (E), Luminex (LMNX)

Background of CD36 antibody

CD36 is a heavily N-glycosylated transmembrane protein of ~88 kDa with two short intracellular domains and a large extracellular domain. The protein is sensitive for neuroaminidase, resulting in a shift from 88 to 85 kDa. CD36 is expressed on platelets, mature monocytes and macrophages, microvascular endothelial cells, mammary endothelial cells, during stages of erythroid cell development and on some macrophage derived dendritic cells. The antibody recognizes adult and fetal monocytes, platelets and reticulocytes, but doesn’t stain lymphocytes and granulocytes. Reactivity has also been found in small intestine, kidney, liver and thyroid. CD36 expression is primarily controlled by the transcription heterodimer PPARg-RXR (peroxisome proliferator-activated receptor-g-retinoid-X-receptor). CD36 is preferentially found within lipid rafts, which facilitates its association with receptors, signaling and adaptor molecules. It is a receptor and transporter of oxidized lipids and long chain fatty acids. CD36 has been implicated in many biological processes including angiogenesis, phagocytosis, inflammation, and lipid and glucose metabolism. Several in vivo models support the role of the thrombospondin / CD36 system in angiogenesis and tumor growth. An important role for CD36 has been found in Malaria as major receptor for P. falciparum-infected red blood cells. CD36 is associated with Src-family kinases and with the integrins α3β1 and α6β1.  Recently, CD36 has been identified as a protein that is required for toll like receptor (TLR2) recognition of di-acylated bacterial lipopeptides and lipoteichoic acid4. Furthermore, CD36 has been shown to function as phagocytic receptor for apoptotic cells. Many different ligands have been reported to interact with CD36, suggesting that CD36 could recognize a structure-based domain rather than specific contact residues.

General readings

General / background references:Thibert V et al. Quantitation of platelet glycoprotein IV (CD36) in healthy subjects and in patients with essential thrombocythemia using an immunocapture assay. Thromb Haemost 68:600-5 (1992). PubMed PMID: 1280864
Kieffer N et al. Developmentally regulated expression of a 78 kDa erythroblast membrane glycoprotein immunologically related to the platelet thrombospondin receptor. Biochem J 262:835-42 (1989). PubMed PMID: 2480109
Edelman P et al. A monoclonal antibody against an erythrocyte ontogenic antigen identifies fetal and adult erythroid progenitors. Blood 67:56-63 (1986). PubMed PMID: 3940553

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CD36 antibody

Figure 1. SM1769A staining of human peripheral blood monocytes. Mouse IgM SM0 Azide Free Hu C, F, FN, WB
1 mg / €810.00
  Acris Antibodies GmbH

CD36 antibody

Immunohistochemical staining of paraffin-embedded liver tissue within the normal limits using anti-CD36mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500921, Dilution 1:50) Mouse IgG1 OTI3F4 Purified Hu ICC/IF, P, WB
0.1 ml / €379.00
  OriGene Technologies, Inc.

TrueMAB

CD36 antibody

Anti-CD36 mouse monoclonal antibody (TA500935) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY CD36(RC203254). Mouse IgG1 OTI4H7 Purified Hu F, ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CD36 antibody

Immunohistochemical staining of paraffin-embedded liver tissue within the normal limits using anti-CD36 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500954, Dilution 1:50) Mouse IgG1 OTI6A5 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CD36 antibody

Immunohistochemical staining of paraffin-embedded Carcinoma of Human prostate tissue using anti-CD36 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA506366) Mouse IgG1 OTI1B3 Purified Hu ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CD36 (99-114) antibody

AP08228PU-N CD36 antibody Staining of Formalin-Fixed Paraffin-Embedded Mouse Spleen Rabbit IgG Aff - Purified Hu, Mky, Ms, Prim E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

CD36 (N-term) antibody

Host: Rabbit Target Name: CD36 Sample Tissue: Human Fetal Heart Antibody Dilution: 1.0ug/ml Rabbit Aff - Purified Bov, Can, Hu, Ms, Por, Rb, Rt P, WB
50 µg / €350.00
  AVIVA Systems Biology

CD36 antibody

Detection of CD36 in human adipocyte extract (30 ug). Lane 1: 0.5 ug/ml anti-CD36; lane 2: 2 ug/ml anti-CD36. ECL: 3 second exposure. Rabbit IgG Purified Bov, Hu, Mky C, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CD36 antibody

Detection of CD36 in human adipocyte extract (30 ug). Lane 1: 0.5 ug/ml anti-CD36; lane 2: 2 ug/ml anti-CD36. ECL: 3 second exposure. Rabbit IgG Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CD36 antibody

Detection of CD36 in mouse adipose lysate Mouse IgA D-2712 Purified Ms, Rt IP, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CD36 antibody

Staining of normal human peripheral blood cells with 0.25 ug of Mouse IgM Isotype Control Purified (open histogram) or 0.25 ug of Anti-Human CD36 Purified  (filled histogram) followed by Anti-Mouse IgM PE .  Cells in the monocyte gate were used for analysis. Mouse eBioNL07 (NL07) Purified Hu F
0.1 mg / €180.00
  OriGene Technologies, Inc.

CD36 antibody

Staining of J774.1 cells with 0.25 ug of Rat IgG2a Isotype Control Purified (open histogram) or 0.25 ug of Anti-Mouse CD36 Purified (filled histogram) followed by Anti-Rat IgG PE .  Total viable cells were used for analysis. Rat No.72-1 Purified Ms F
50 µg / €120.00
  OriGene Technologies, Inc.

CD36 antibody

Western blot analysis of extracts of various cell lines, using CD36 antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

CD36 antibody

Western Blot: CD36 Antibody [TA337173] - Analysis of CD36 in human platelets using this antibody at 1:200. Rabbit Purified Hu WB
0.15 mg / €325.00
  OriGene Technologies, Inc.

CD36 antibody

CD36 ELISA with 3F4 Capture (TA600031) and 4H7 Detection (TA700031) Antibodies. Substrate used: Recombinant Human CD36 (TP303254) Mouse IgG1 OTI3F4 Purified Hu E, LMNX
0.1 mg / €325.00
  OriGene Technologies, Inc.

CD36 antibody

CD36 ELISA with 6A5 Capture (TA600044) and 4H7 Detection (TA700031) Antibodies. Substrate used: Recombinant Human CD36 (TP303254) Mouse IgG1 OTI6A5 Purified Hu E, LMNX
0.1 mg / €325.00
  OriGene Technologies, Inc.

CD36 antibody

CD36 ELISA with 3F4 Capture (TA600031) and 4H7 Detection (TA700031) Antibodies. Substrate used: Recombinant Human CD36 (TP303254) Mouse IgG1 OTI4H7 Purified Hu E, LMNX
50 µg / €345.00
  OriGene Technologies, Inc.

CD36 antibody

Surface staining of human platelets with anti-CD36 (TR9) FITC. Mouse IgG1 TR9 APC Hu F
100 Tests / €290.00
  Acris Antibodies GmbH

CD36 antibody

Surface staining of human platelets with anti-CD36 (TR9) FITC. Mouse IgG1 TR9 FITC Hu F
100 Tests / €260.00
  Acris Antibodies GmbH

CD36 antibody

Surface staining of Human platelets with anti-CD36 antibody (TR9) FITC. Mouse IgG1 TR9 Purified Hu F
0.1 mg / €210.00
  Acris Antibodies GmbH

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