CD42b / GPIbA antibody

Principal name

CD42b / GPIbA antibody

Alternative names for CD42b / GPIbA antibody

Platelet glycoprotein Ib alpha chain, Glycoprotein Ibalpha, GP-Ib alpha, GPIb-alpha

SwissProt ID

O35930 (Mouse), P07359 (Human), Q28256 (Canfa)

Gene ID

2811 (GP1BA), 14723 (Gp1ba)

Available reactivities

Can (Canine), Hu (Human), Ms (Mouse), Prim (Primate), Rt (Rat), Eq (Equine), Rb (Rabbit), GP (Guinea Pig)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Frozen Sections (C), Functional assay (FN), Flow Cytometry (F), Enzyme Immunoassay (E), EPair for Elisa (EPair), ELISA (detection) (E(detection)), Immunoprecipitation (IP), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P)

Background of CD42b / GPIbA antibody

Glycoprotein Ib (GP Ib) is a platelet surface membrane glycoprotein composed of a heterodimer, an alpha chain and a beta chain, that are linked by disulfide bonds. The Gp Ib functions as a receptor for von Willebrand factor (VWF). The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX and platelet glycoprotein V. The binding of the GP Ib-IX-V complex to VWF facilitates initial platelet adhesion to vascular subendothelium after vascular injury, and also initiates signaling events within the platelet that lead to enhanced platelet activation, thrombosis, and hemostasis. GP1BA is the alpha subunit.Glycoprotein Ib (GP Ib) is a platelet surface membrane glycoprotein composed of a heterodimer, an alpha chain and a beta chain, that are linked by disulfide bonds. The Gp Ib functions as a receptor for von Willebrand factor (VWF). The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX and platelet glycoprotein V. The binding of the GP Ib-IX-V complex to VWF facilitates initial platelet adhesion to vascular subendothelium after vascular injury, and also initiates signaling events within the platelet that lead to enhanced platelet activation, thrombosis, and hemostasis. This gene encodes the alpha subunit. Several polymorphisms and mutations have been described in this gene, some of which are the cause of Bernard-Soulier syndromes and platelet-type von Willebrand disease. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

General readings

Mazurov, A., et al., 1991, Thromb. Res. 62, 673-684.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CD42b / GPIbA antibody

  Mouse Anti-Human CD42b Purified (100 ug)  
Staining of human platelets with Anti-Human CD42b FITC (left) and PE (right).  Appropriate isotype controls were used (open histogram).  Total cells were used for analysis. Mouse HIP1 Purified Hu F, P, WB
0.1 mg / €120.00
  OriGene Technologies, Inc.

CD42b / GPIbA antibody

  Rabbit Polyclonal Anti-GP1BA  
WB Suggested Anti-GP1BA Antibody Titration: 0.2-1 ug/ml; Positive Control: Jurkat cell lysate Rabbit IgG Purified Can, Eq, Hu, Ms, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

CD42b / GPIbA antibody

  Rabbit Polyclonal Anti-GP1BA  
Host: Rabbit; Target Name: GP1BA; Sample Tissue: Jurkat Whole Cell lysates; Antibody Dilution: 1.0 ug/ml Rabbit IgG Purified GP, Hu, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

CD42b / GPIbA antibody

  Rabbit Polyclonal Anti-GP1BA Antibody  
Gel: 6%SDS-PAGE, Lysate: 40 ug, Lane: Mouse liver tissue, Primary antibody: (GP1BA Antibody) at dilution 1/800, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute Rabbit IgG Purified Hu, Ms E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CD42b / GPIbA antibody

  Rabbit Monoclonal anti-CD42b Antibody  
CD42b / GPIbA Rabbit IgG SP202. Purified Hu P
0.1 ml / €325.00
  OriGene Technologies, Inc.

CD42b / GPIbA antibody

  Rabbit Monoclonal anti-CD42b Antibody  
CD42b / GPIbA Rabbit IgG SP219 Purified Hu F, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

CD42b / GPIbA antibody

CD42b / GPIbA Mouse IgG1 VM16d Purified Hu ICC/IF
1 ml / €350.00
  Acris Antibodies GmbH

CD42b / GPIbA antibody

CD42b / GPIbA Mouse IgG1 SZ2 Azide Free Hu C, F, FN
0.2 mg / €580.00
  Acris Antibodies GmbH

CD42b / GPIbA antibody

Staining of human peripheral blood platelets with Mouse Anti Human CD42b-Biotin Mouse IgG1 AK2 Biotin Hu F
0.1 mg / €420.00
  Acris Antibodies GmbH

CD42b / GPIbA antibody

Staining of human peripheral blood platelets with Mouse Anti Human CD42b-Biotin Mouse IgG1 AK2 Biotin Hu F
25 µg / €210.00
  Acris Antibodies GmbH

CD42b / GPIbA antibody

Staining of human peripheral blood platelets with Mouse Anti Human CD42b-FITC Mouse IgG1 AK2 FITC Hu F
0.1 mg / €380.00
  Acris Antibodies GmbH

CD42b / GPIbA antibody

CD42b / GPIbA Mouse IgG1 AK2 Low Endotoxin Hu E, F, FN, IP
0.5 mg / €540.00
  Acris Antibodies GmbH

CD42b / GPIbA antibody

Staining of human peripheral blood platelets with MOUSE ANTI HUMAN CD42b Mouse IgG1 AK2 Purified Hu F
0.2 mg / €430.00
  Acris Antibodies GmbH

CD42b / GPIbA antibody

CD42b / GPIbA Mouse IgG1 AK2 Purified Hu F
0.1 mg / €270.00
  Acris Antibodies GmbH

CD42b / GPIbA antibody

CD42b / GPIbA Mouse IgG1 AK2 Purified Hu F
25 µg / €180.00
  Acris Antibodies GmbH

CD42b / GPIbA antibody

Staining of human peripheral blood platelets with Mouse Anti Human CD42b-RPE (SM1105R/RT). Mouse IgG1 AK2 PE Hu F
100 Tests / €470.00
  Acris Antibodies GmbH

CD42b / GPIbA antibody

Staining of human peripheral blood platelets with Mouse Anti Human CD42b-RPE (SM1105R/RT). Mouse IgG1 AK2 PE Hu F
25 Tests / €210.00
  Acris Antibodies GmbH

CD42b / GPIbA antibody

Surface staining of human platelets with anti-CD42b PE (SM3082R) Mouse IgG1 HIP1 APC Hu, Prim F
100 Tests / €290.00
  Acris Antibodies GmbH

CD42b / GPIbA antibody

CD42b / GPIbA Mouse IgG1 HIP1 Azide Free Hu, Prim C, F, FN
0.1 mg / €220.00
  Acris Antibodies GmbH

CD42b / GPIbA antibody

Surface staining of human peripheral blood with anti-CD42b (HIP1) purified / GAM-APC. Mouse IgG1 HIP1 Purified Hu, Prim C, F, FN
0.1 mg / €220.00
  Acris Antibodies GmbH

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