CD42b / GPIbA antibody

Principal name

CD42b / GPIbA antibody

Alternative names for CD42b / GPIbA antibody

Platelet glycoprotein Ib alpha chain, Glycoprotein Ibalpha, GP-Ib alpha, GPIb-alpha

SwissProt ID

O35930 (Mouse), P07359 (Human), Q28256 (Canfa)

Gene ID

2811

Available reactivities

Hu (Human), Prim (Primate), Mky (Monkey), Can (Canine), Ms (Mouse), Rt (Rat), Eq (Equine), Rb (Rabbit), GP (Guinea Pig)

Available hosts

Mouse, Rabbit

Available applications

Frozen Sections (C), Functional assay (FN), Flow Cytometry (F), Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunoprecipitation (IP), ELISA (detection) (E(detection)), EPair for Elisa (EPair), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of CD42b / GPIbA antibody

Glycoprotein Ib (GP Ib) is a platelet surface membrane glycoprotein composed of a heterodimer, an alpha chain and a beta chain, that are linked by disulfide bonds. The Gp Ib functions as a receptor for von Willebrand factor (VWF). The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX and platelet glycoprotein V. The binding of the GP Ib-IX-V complex to VWF facilitates initial platelet adhesion to vascular subendothelium after vascular injury, and also initiates signaling events within the platelet that lead to enhanced platelet activation, thrombosis, and hemostasis. GP1BA is the alpha subunit.Glycoprotein Ib (GP Ib) is a platelet surface membrane glycoprotein composed of a heterodimer, an alpha chain and a beta chain, that are linked by disulfide bonds. The Gp Ib functions as a receptor for von Willebrand factor (VWF). The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX and platelet glycoprotein V. The binding of the GP Ib-IX-V complex to VWF facilitates initial platelet adhesion to vascular subendothelium after vascular injury, and also initiates signaling events within the platelet that lead to enhanced platelet activation, thrombosis, and hemostasis. This gene encodes the alpha subunit. Several polymorphisms and mutations have been described in this gene, some of which are the cause of Bernard-Soulier syndromes and platelet-type von Willebrand disease. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

General readings

This product has been used in:Kishimoto T. et al. (Eds.) Leuccyte typing VI. Garland Publishing Inc. : (1997).

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CD42b / GPIbA antibody

Staining of human platelets with Anti-Human CD42b FITC (left) and PE (right).  Appropriate isotype controls were used (open histogram).  Total cells were used for analysis. Mouse HIP1 Purified Hu F, P, WB
0.1 mg / €120.00
  OriGene Technologies, Inc.

CD42b / GPIbA antibody

WB Suggested Anti-GP1BA Antibody Titration: 0.2-1 ug/ml; Positive Control: Jurkat cell lysate Rabbit IgG Purified Can, Eq, Hu, Ms, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

CD42b / GPIbA antibody

Host: Rabbit; Target Name: GP1BA; Sample Tissue: Jurkat Whole Cell lysates; Antibody Dilution: 1.0 ug/ml Rabbit IgG Purified GP, Hu, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

CD42b / GPIbA antibody

CD42b / GPIbA Mouse IgG1 VM16d Purified Hu ICC/IF
1 ml / €350.00
  Acris Antibodies GmbH

CD42b / GPIbA (C-term) antibody

Human spleen stained with anti-CD42b Antibody Cat.-No AM33234PU (Clone SP219). Rabbit IgG SP219 Purified Can, Hu, Ms F, P
0.5 ml / €520.00
  Acris Antibodies GmbH

CD42b / GPIbA (C-term) antibody

Human spleen stained with anti-CD42b Antibody Cat.-No AM33234PU (Clone SP219). Rabbit IgG SP219 Purified Can, Hu, Ms F, P
1 ml / €730.00
  Acris Antibodies GmbH

CD42b / GPIbA (C-term) antibody

Human spleen stained with anti-CD42b Antibody Cat.-No AM33234PU (Clone SP219). Rabbit IgG SP219 Purified Can, Hu, Ms F, P
0.1 ml / €300.00
  Acris Antibodies GmbH

CD42b / GPIbA antibody

CD42b / GPIbA Mouse IgG1 SZ2 Azide Free Hu C, F, FN
0.2 mg / €540.00
  Acris Antibodies GmbH

CD42b / GPIbA antibody

Staining of human peripheral blood platelets with Mouse Anti Human CD42b-Biotin Mouse IgG1 AK2 Biotin Hu F
0.1 mg / €420.00
  Acris Antibodies GmbH

CD42b / GPIbA antibody

Staining of human peripheral blood platelets with Mouse Anti Human CD42b-Biotin Mouse IgG1 AK2 Biotin Hu F
25 µg / €210.00
  Acris Antibodies GmbH

CD42b / GPIbA antibody

Staining of human peripheral blood platelets with Mouse Anti Human CD42b-FITC Mouse IgG1 AK2 FITC Hu F
0.1 mg / €380.00
  Acris Antibodies GmbH

CD42b / GPIbA antibody

CD42b / GPIbA Mouse IgG1 AK2 Low Endotoxin Hu F, FN
0.5 mg / €540.00
  Acris Antibodies GmbH

CD42b / GPIbA antibody

Staining of human peripheral blood platelets with MOUSE ANTI HUMAN CD42b Mouse IgG1 AK2 Purified Hu F
0.2 mg / €430.00
  Acris Antibodies GmbH

CD42b / GPIbA antibody

CD42b / GPIbA Mouse IgG1 AK2 Purified Hu F
0.1 mg / €270.00
  Acris Antibodies GmbH

CD42b / GPIbA antibody

CD42b / GPIbA Mouse IgG1 AK2 Purified Hu F
25 µg / €180.00
  Acris Antibodies GmbH

CD42b / GPIbA antibody

Staining of human peripheral blood platelets with Mouse Anti Human CD42b-RPE (SM1105R/RT). Mouse IgG1 AK2 PE Hu F
100 Tests / €470.00
  Acris Antibodies GmbH

CD42b / GPIbA antibody

Staining of human peripheral blood platelets with Mouse Anti Human CD42b-RPE (SM1105R/RT). Mouse IgG1 AK2 PE Hu F
25 Tests / €210.00
  Acris Antibodies GmbH

CD42b / GPIbA antibody

Surface staining of human platelets with anti-CD42b PE (SM3082R) Mouse IgG1 HIP1 APC Hu, Prim F
100 Tests / €290.00
  Acris Antibodies GmbH

CD42b / GPIbA antibody

CD42b / GPIbA Mouse IgG1 HIP1 Azide Free Hu, Prim C, F, FN
0.1 mg / €220.00
  Acris Antibodies GmbH

CD42b / GPIbA antibody

Surface staining of human platelets with anti-CD42b antibody (HIP1) PE. Mouse IgG1 HIP1 Purified Hu, Prim C, F, FN
0.1 mg / €220.00
  Acris Antibodies GmbH

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