CD49a / ITGA1 antibody

Principal name

CD49a / ITGA1 antibody

Alternative names for CD49a / ITGA1 antibody

Integrin alpha-1, ITGA-1, VLA-1, VLA1, Laminin and Collagen Receptor, CD49 antigen-like family member A

SwissProt ID

P18614 (Rat), P56199 (Human), Q3V3R4 (Mouse), Q90615 (Chick)

Gene ID

3672 (ITGA1), 311144

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Chk (Chicken), Eq (Equine), Gt (Goat), Hst (Hamster), Mky (Monkey), Por (Porcine), Sh (Sheep), Can (Canine), GP (Guinea Pig), Rb (Rabbit)

Available hosts

Mouse, Rabbit, Goat

Available applications

Flow Cytometry (F), Frozen Sections (C), Immunoprecipitation (IP), Enzyme Immunoassay (E), Paraffin Sections (P), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Radioimmunoassay (R), Neutralisation (NEUT)

Background of CD49a / ITGA1 antibody

Integrins are important extracellular matrix (ECM) receptor proteins located on cell surfaces. They are hetrodimers composed of an alpha and a beta transmembrane glycoprotein subunit. Around twenty two different integrins (different alpha/ beta subunit combinations) are found in nature. Integrins are generally present in high concentrations at the cell surface, but, unlike most other cell surface receptors, they bind ligands with very low affinity. Due to their weak individual binding, integrins need to cluster and bind in groups in order to effectively bind the ECM. Integrins bind many different ligands including laminin. Each integrin is made up of a large N terminal extracellular domain that binds the ECM ligand and a small C terminal cytoplasmic domain that mediates interaction with the actin cytoskeleton and signaling function. Alpha 1 integrin along with alpha 2, alpha L and alpha M has a unique inserted domain. Integrin alpha 1 is a receptor for laminin and collagen. The alpha1 subunit is also known as CD49a. CD49a associates with CD29 (beta 1 integrin), to form an alpha1 beta1 heterodimer, identified as the rat homologue to VLA1, which is involved in cellular adhesion to laminin and collagen.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CD49a / ITGA1 antibody

TA341376 (0.5µg/ml) staining of HeLa (A) and HepG2 (B) lysates (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CD49a / ITGA1 antibody

Western blot analysis of ITGA1 Antibody (Center) (AP18077PU-N) in Hela cell line lysates (35ug/lane). ITGA1 (arrow) was detected using the purified Pab. Rabbit Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CD49a / ITGA1 (N-term) antibody

Western blot analysis of Hela cell lysate using ITGA1 antibody Rabbit IgG Aff - Purified Hu, Ms, Rt WB
0.1 mg / €340.00
  Acris Antibodies GmbH

CD49a / ITGA1 antibody

CD49a / ITGA1 Mouse IgG1 TS2/7 Biotin Hu F
0.1 mg / €430.00
  Acris Antibodies GmbH

CD49a / ITGA1 antibody

Staining of HeLa cells with Mouse Anti Human CD49a-FITC (SM1122F/FT). Mouse IgG1 TS2/7 FITC Hu F
0.1 mg / €380.00
  Acris Antibodies GmbH

CD49a / ITGA1 antibody

Staining of HeLa cells with Mouse Anti Human CD49a-FITC (SM1122F/FT). Mouse IgG1 TS2/7 FITC Hu F
25 µg / €190.00
  Acris Antibodies GmbH

CD49a / ITGA1 antibody

Staining of HeLa cells with MOUSE ANTI HUMAN CD49a (SM1122PS). Mouse IgG1 TS2/7 Purified Hu C, F, IP
0.2 mg / €590.00
  Acris Antibodies GmbH

CD49a / ITGA1 antibody

CD49a / ITGA1 Mouse IgG1 TS2/7 PE Hu F
100 Tests / €470.00
  Acris Antibodies GmbH

CD49a / ITGA1 antibody

CD49a / ITGA1 Mouse IgG1 TS2/7 PE Hu F
25 Tests / €220.00
  Acris Antibodies GmbH

CD49a / ITGA1 antibody

CD49a / ITGA1 Mouse Serum Hu E
50 µl / €290.00
  Abnova Taiwan Corp.

CD49a / ITGA1 antibody

ITGA1 MaxPab polyclonal antibody. Western Blot analysis of ITGA1 expression in human spleen. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

CD49a / ITGA1 antibody

CD49a / ITGA1 Mouse IgG2a 4G11 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

CD49a / ITGA1 antibody

CD49a / ITGA1 Mouse IgG1 TS2/7 Hu C, F, IP
0.5 ml / €990.00
  Abnova Taiwan Corp.

CD49a / ITGA1 antibody

Flow Cytometry: CD49a Antibody (TS2/7) [NB100-63872] - Staining of HeLa cells with MOUSE ANTI HUMAN CD49a Mouse IgG1 TS2/7 Biotin Hu F, P
0.1 mg / €430.00
  Novus Biologicals Inc.

CD49a / ITGA1 antibody

Flow Cytometry: CD49a Antibody (TS2/7) [NB100-63873] - Staining of HeLa cells with MOUSE ANTI HUMAN CD49a:FITC Mouse IgG1 TS2/7 FITC Hu F, P
0.1 mg / €390.00
  Novus Biologicals Inc.

CD49a / ITGA1 antibody

CD49a / ITGA1 Mouse IgG1 TS2/7 PE Hu F
50 Tests / €300.00
  Novus Biologicals Inc.

CD49a / ITGA1 antibody

Immunohistochemistry-Paraffin: Integrin alpha 1 Antibody [NBP1-84577] Immunohistochemical staining of human colon shows moderate cytoplasmic positivity in glandular cells. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

CD49a / ITGA1

CD49a / ITGA1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

CD49a / ITGA1

CD49a / ITGA1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

ITGA1 293T Cell Transient Overexpression Lysate(Denatured)

ITGA1 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

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