CD49c / ITGA3 antibody

Principal name

CD49c / ITGA3 antibody

Alternative names for CD49c / ITGA3 antibody

Integrin alpha-3, ITGA-3, ITGAG3, MSK18, Galactoprotein B3, GAPB3, VLA-3 alpha chain, VLA3, FRP-2, CD49 antigen-like family member C

SwissProt ID

P26006 (Human), Q62470 (Mouse)

Gene ID

3675 (ITGA3), 16400 (Itga3)

Available reactivities

Hu (Human), Can (Canine), Ms (Mouse), Rt (Rat), Bt (Bat), Eq (Equine), Hst (Hamster), Mky (Monkey), Gorilla, Rb (Rabbit)

Available hosts

Mouse, Rabbit

Available applications

Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Flow Cytometry (F), Paraffin Sections (P), Immunoprecipitation (IP)

Background of CD49c / ITGA3 antibody

Integrins are heterodimers composed of non-covalently associated transmembrane α and β subunits. The 16 α and 8 β subunits heterodimerize to produce more than 20 different receptors. Most integrin receptors bind ligands that are components of the extracellular matrix, including fibronectin, collagen and vitronectin. Certain integrins can also bind to soluble ligands such as fibrinogen, or to counterreceptors on adjacent cells such as the intracellular adhesion molecules (ICAMs), leading to aggregation of cells. Ligands serve to cross-link or cluster integrins by binding to adjacent integrin receptors; both receptor clustering and ligand occupancy are necessary for the activation of integrin-mediated responses. In addition to mediating cell adhesion and cytoskeletal organization, integrins function as signaling receptors. Signals transduced by integrins play a role in many biological processes, including cell growth, differentiation, migration and apoptosis. The Integrin α3 chain, also known as very late (activation) antigen 3 (VLA-3), very common antigen 2 (VCA-2), extracellular matrix receptor 1 (ECMR1) and galactoprotein b3 (GAPB3), undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with β1 to form an integrin that interacts with many extracellular-matrix proteins.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CD49c / ITGA3 antibody

Anti-ITGA3 / CD49c antibody IHC of human colon, smooth muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit IgG Purified Bt, Can, Eq, Gorilla, Hst, Hu, Mky, Ms
50 µg / €345.00
  OriGene Technologies, Inc.

CD49c / ITGA3 antibody

Anti-ITGA3 / CD49c antibody IHC of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit IgG Purified Gorilla, Hst, Hu, Mky, Rb
50 µg / €345.00
  OriGene Technologies, Inc.

CD49c / ITGA3 antibody

Staining of URO-1 (J143) on frozen human kidney tissue. Mouse IgG1 J143 Purified Hu P
1 ml / €379.00
  OriGene Technologies, Inc.

CD49c / ITGA3 antibody

Staining of CD49C (Integrin alpha;3) (Clone P1B5), on forzen normal human kidney tissue at 1:250. Mouse IgG1 P1B5 Purified Hu ICC/IF, IP, P
100 µl / €325.00
  OriGene Technologies, Inc.

CD49c / ITGA3 antibody

CD49c / ITGA3 Mouse IgG1 F35 177-1 Purified Hu ICC/IF, P
0.1 mg / €325.00
  OriGene Technologies, Inc.

CD49c / ITGA3 antibody

CD49c / ITGA3 Mouse IgG1 IA3 Purified Hu F, P
0.1 mg / €325.00
  OriGene Technologies, Inc.

CD49c / ITGA3 antibody

Western blot (WB) analysis of CD49c / ITGA3 Antibody Cat.-No. AP20567PU-N at 1/500 dilution. Lane 1: HepG2 whole cell lysate. Lane 2: Raw264.7 whole cell lysate. Lane 3: PC12 whole cell lysate. Rabbit Aff - Purified Hu, Ms, Rt WB
0.1 mg / €350.00
  Acris Antibodies GmbH

CD49c / ITGA3 (3A Isoform specific) antibody

Immunohistochemistry on frozen section of Human kidney. Mouse IgG1 29A3 Purified Hu C, ICC/IF, WB
0.1 mg / €340.00
  Acris Antibodies GmbH

CD49c / ITGA3 (3A Isoform specific) antibody

Immunohistochemistry on frozen section of Human skin. Mouse IgG2a 158A3 Purified Can, Hu C, ICC/IF, WB
0.1 mg / €340.00
  Acris Antibodies GmbH

CD49c / ITGA3 (3B Isoform specific) antibody

CD49c / ITGA3 Mouse IgG1 54B3 Purified Hu C, ICC/IF, WB
0.1 mg / €340.00
  Acris Antibodies GmbH

CD49c / ITGA3 antibody

CD49c / ITGA3 Mouse IgG1 17C6 FITC Hu F
0.1 mg / €380.00
  Acris Antibodies GmbH

CD49c / ITGA3 antibody

CD49c / ITGA3 Mouse IgG1 17C6 FITC Hu F
25 µg / €190.00
  Acris Antibodies GmbH

CD49c / ITGA3 antibody

CD49c / ITGA3 Mouse IgG1 17C6 Purified Hu C, F
0.1 mg / €270.00
  Acris Antibodies GmbH

CD49c / ITGA3 antibody

CD49c / ITGA3 Mouse IgG1 17C6 Purified Hu C, F
25 µg / €180.00
  Acris Antibodies GmbH

CD49c / ITGA3 antibody

SM1544R/RT staining of KG1a cell line. Mouse IgG1 17C6 PE Hu F
100 Tests / €470.00
  Acris Antibodies GmbH

CD49c / ITGA3 antibody

SM1544R/RT staining of KG1a cell line. Mouse IgG1 17C6 PE Hu F
25 Tests / €220.00
  Acris Antibodies GmbH

CD49c / ITGA3 antibody

CD49c / ITGA3 Mouse IgG1 VJ1/6 Hu F, ICC/IF
0.1 mg / €390.00
  Abnova Taiwan Corp.

CD49c / ITGA3 antibody

CD49c / ITGA3 Rabbit IgG Aff - Purified Hu, Ms, Rt P, WB
0.1 mg / €290.00
  Boster Immunoleader

CD49c / ITGA3 antibody

Western blot analysis of CD49c expression in Caki1 (A); HL60 (B) whole cell lysates. Rabbit Aff - Purified Hu, Ms WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

CD49c / ITGA3 antibody

Western blot analysis of CD49c expression in Caki1 (A); HL60 (B) whole cell lysates. Rabbit Aff - Purified Hu, Ms WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

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