CD49c / ITGA3 antibody

Principal name

CD49c / ITGA3 antibody

Alternative names for CD49c / ITGA3 antibody

Integrin alpha-3, ITGA-3, ITGAG3, MSK18, Galactoprotein B3, GAPB3, VLA-3 alpha chain, VLA3, FRP-2, CD49 antigen-like family member C

SwissProt ID

P26006 (Human), Q62470 (Mouse)

Gene ID

3675 (ITGA3), 16400 (Itga3)

Available reactivities

Hu (Human), Can (Canine), Ms (Mouse), Rt (Rat), Bt (Bat), Eq (Equine), Hst (Hamster), Mky (Monkey), Gorilla, Rb (Rabbit)

Available hosts

Mouse, Rabbit

Available applications

Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Flow Cytometry (F), Paraffin Sections (P), Immunoprecipitation (IP)

Background of CD49c / ITGA3 antibody

Integrins are heterodimers composed of non-covalently associated transmembrane α and β subunits. The 16 α and 8 β subunits heterodimerize to produce more than 20 different receptors. Most integrin receptors bind ligands that are components of the extracellular matrix, including fibronectin, collagen and vitronectin. Certain integrins can also bind to soluble ligands such as fibrinogen, or to counterreceptors on adjacent cells such as the intracellular adhesion molecules (ICAMs), leading to aggregation of cells. Ligands serve to cross-link or cluster integrins by binding to adjacent integrin receptors; both receptor clustering and ligand occupancy are necessary for the activation of integrin-mediated responses. In addition to mediating cell adhesion and cytoskeletal organization, integrins function as signaling receptors. Signals transduced by integrins play a role in many biological processes, including cell growth, differentiation, migration and apoptosis. The Integrin α3 chain, also known as very late (activation) antigen 3 (VLA-3), very common antigen 2 (VCA-2), extracellular matrix receptor 1 (ECMR1) and galactoprotein b3 (GAPB3), undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with β1 to form an integrin that interacts with many extracellular-matrix proteins.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CD49c / ITGA3 antibody

  ITGA3 / CD49c Rabbit Polyclonal (N-Terminus) Antibody  
Anti-ITGA3 / CD49c antibody IHC of human colon, smooth muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit IgG Purified Bt, Can, Eq, Gorilla, Hst, Hu, Mky, Ms
50 µg / €400.00
  OriGene Technologies, Inc.

CD49c / ITGA3 antibody

  ITGA3 / CD49c Rabbit Polyclonal (Internal) Antibody  
Anti-ITGA3 / CD49c antibody IHC of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit IgG Purified Gorilla, Hst, Hu, Mky, Rb
50 µg / €400.00
  OriGene Technologies, Inc.

CD49c / ITGA3 antibody

  Mouse monoclonal Anti-Integrin a3 Clone IA3  
CD49c / ITGA3 Mouse IgG1 IA3 Purified Hu F, P
0.1 mg / €325.00
  OriGene Technologies, Inc.

CD49c / ITGA3 antibody

Western blot (WB) analysis of CD49c / ITGA3 Antibody Cat.-No. AP20567PU-N at 1/500 dilution. Lane 1: HepG2 whole cell lysate. Lane 2: Raw264.7 whole cell lysate. Lane 3: PC12 whole cell lysate. Rabbit Aff - Purified Hu, Ms, Rt WB
0.1 mg / €350.00
  Acris Antibodies GmbH

CD49c / ITGA3 (3A Isoform specific) antibody

Immunohistochemistry on frozen section of Human kidney. Mouse IgG1 29A3 Purified Hu C, ICC/IF, WB
0.1 mg / €340.00
  Acris Antibodies GmbH

CD49c / ITGA3 (3A Isoform specific) antibody

Immunohistochemistry on frozen section of Human skin. Mouse IgG2a 158A3 Purified Can, Hu C, ICC/IF, WB
0.1 mg / €340.00
  Acris Antibodies GmbH

CD49c / ITGA3 (3B Isoform specific) antibody

CD49c / ITGA3 Mouse IgG1 54B3 Purified Hu C, ICC/IF, WB
0.1 mg / €340.00
  Acris Antibodies GmbH

CD49c / ITGA3 antibody

CD49c / ITGA3 Mouse IgG1 17C6 FITC Hu F
0.1 mg / €380.00
  Acris Antibodies GmbH

CD49c / ITGA3 antibody

CD49c / ITGA3 Mouse IgG1 17C6 FITC Hu F
25 µg / €190.00
  Acris Antibodies GmbH

CD49c / ITGA3 antibody

CD49c / ITGA3 Mouse IgG1 17C6 Purified Hu C, F
0.1 mg / €270.00
  Acris Antibodies GmbH

CD49c / ITGA3 antibody

CD49c / ITGA3 Mouse IgG1 17C6 Purified Hu C, F
25 µg / €180.00
  Acris Antibodies GmbH

CD49c / ITGA3 antibody

SM1544R/RT staining of KG1a cell line. Mouse IgG1 17C6 PE Hu F
100 Tests / €470.00
  Acris Antibodies GmbH

CD49c / ITGA3 antibody

SM1544R/RT staining of KG1a cell line. Mouse IgG1 17C6 PE Hu F
25 Tests / €220.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

ITGA3 - human gene knockout kit via CRISPR

ITGA3 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

ITGA3 - human gene knockout kit via CRISPR

ITGA3 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

ITGA3 - human gene knockout kit via CRISPR

ITGA3 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

ITGA3 - human gene knockout kit via CRISPR

ITGA3 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Itga3 - mouse gene knockout kit via CRISPR

Itga3 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Itga3 - mouse gene knockout kit via CRISPR

Itga3 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Itga3 - mouse gene knockout kit via CRISPR

Itga3 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

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