CD52 / CAMPATH-1 antibody

Principal name

CD52 / CAMPATH-1 antibody

Alternative names for CD52 / CAMPATH-1 antibody

HE5, CDw52, Cambridge pathology 1 antigen, Epididymal secretory protein E5

SwissProt ID

P31358 (Human), Q28896 (Canfa), Q63064 (Rat), Q64389 (Mouse)

Gene ID

1043 (CD52), 23833 (Cd52)

Available reactivities

Hu (Human), Mky (Monkey), Rhesus Mky (Rhesus Monkey), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rat, Rabbit

Available applications

Frozen Sections (C), Flow Cytometry (F), Paraffin Sections (P), Cytotoxicity Assay (CT), Enzyme Immunoassay (E), Immunoprecipitation (IP), Western blot / Immunoblot (WB)

Background of CD52 / CAMPATH-1 antibody

CAMPATH-1, also known as CD52, is a heavily glycosylated, GPI-anchored protein expressed at high levels on almost all thymocytes, lymphocytes, monocytes, and macrophages. The function of CD52 is unknown. However, CD52 is an exceptionally good target for complement-mediated cell lysis and antibody-mediated cellular cytotoxicity. Humanized CAMPATH-1antibodies have been used therapeutically to effectively deplete lymphocytes in allogeneic bone marrow transplants, hematologic malignancies, and autoimmune diseases. Clinical trials suggest CAMPATH-1 antibodies are especially promising in the treatment of leukemia, non-Hodgkin lymphomas, and rheumatoid arthritis. The apparent size of CAMPATH-1 by SDS-PAGE is 25-29 kDa; however, the actual molecule is much smaller, ~ 8-9 kDa as confirmed by total structure analysis and mass spectrometry.

General readings

Kishimoto T. et al. (Eds.) Leucocyte typing VI. Garland Publishing Inc. : (1997).

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CD52 / CAMPATH-1 antibody

Figure 2. CD52 negative pro T ALL (gate leukemic cells). Mouse IgG2b HI186 Purified Hu C, F, P
0.1 mg / €230.00
  Acris Antibodies GmbH

CD52 / CAMPATH-1 antibody

CD52 / CAMPATH-1 Rat IgM YTH66.9HL Purified Hu, Mky C, CT, F, WB
0.1 ml / €600.00
  Acris Antibodies GmbH

CD52 / CAMPATH-1 antibody

Immunoprecipitation of mouse CAMPATH-1 from Mouse splenocytes with rat IgG2a (1) or AM26521AF-N (2) . After immunoprecipitated with the antibody, immunocomplex was resolved on SDS-PAGE and immunoblotted with HRP-Streptavidin. Rat IgG2a BTG-2G Azide Free Ms F, IP
0.1 mg / €300.00
  Acris Antibodies GmbH

CD52 / CAMPATH-1 antibody

Flow cytometric analysis of mouse CD52/CAMPATH-1 expression on mouse splenocytes. Open histogram indicates the reaction of isotypic control to the cells. Shaded histogram indicates the reaction of AM26521FC-N to the cells. Rat IgG2a BTG-2G FITC Ms F
0.1 ml / €280.00
  Acris Antibodies GmbH

CD52 / CAMPATH-1 antibody

Flow cytometric analysis of mouse CD52 expression on mouse splenocyte. Open histogram indicates the reaction of isotypic control to the cells. Shaded histogram indicates the reaction of AM26521RP-N to the cells. Rat IgG2a BTG-2G PE Ms F
50 Tests / €340.00
  Acris Antibodies GmbH

CD52 / CAMPATH-1 antibody

Staining of human peripheral blood lymphocytes with RAT ANTI HUMAN CD52:FITC (SM2135F) Rat IgG2b YTH34.5 FITC Hu, Mky F
0.1 mg / €550.00
  Acris Antibodies GmbH

CD52 / CAMPATH-1 antibody

Staining of human peripheral blood lymphocytes with RAT Anti Human CD52:LOW ENDOTOXIN (SM2135LE) Rat IgG2b YTH34.5 Low Endotoxin Hu, Mky C, CT, E, F, IP, P, WB
0.5 mg / €670.00
  Acris Antibodies GmbH

CD52 / CAMPATH-1 antibody

CD52 / CAMPATH-1 Rat IgG2b YTH34.5 Purified Hu, Mky C, CT, E, F, IP, P, WB
0.2 mg / €670.00
  Acris Antibodies GmbH

CD52 / CAMPATH-1 antibody

Staining of human peripheral blood lymphocytes with rat anti human CD52-PE (SM2135R). Rat IgG2b YTH34.5 PE Hu, Mky, Rhesus Mky F
100 Tests / €800.00
  Acris Antibodies GmbH

CD52 / CAMPATH-1 antibody

Flow cytometry analysis of CD52 in patients suffering with Acute Lymphoblastic Leukemia (anti-human CD52 (HI186); detection by Goat anti-mouse IgG2b PE).
Fig. 1A – CD52 positive cALL (gate leukemic cells)
Fig. 1B – CD52 negative pro T ALL (gate leukemic cells) Mouse IgG2b HI186 APC Hu F
100 Tests / €290.00
  Acris Antibodies GmbH

CD52 / CAMPATH-1 antibody

Staining of Human peripheral blood lymphocytes with Mouse Anti Human CD52 Antibody -FITC Cat.-No SM3081F (Clone HI186). Mouse IgG2b HI186 FITC Hu F
0.1 mg / €530.00
  Acris Antibodies GmbH

CD52 / CAMPATH-1 antibody

Figure 2. CD52 negative pro T ALL (gate leukemic cells). Mouse IgG2b HI186 PE Hu F
100 Tests / €290.00
  Acris Antibodies GmbH

CD52 / CAMPATH-1 antibody

Flow cytometry analysis of CD52 in patients suffering with Acute Lymphoblastic Leukemia ( CD52 monoclonal antibody, clone HI186, Cat # MAB0944 ; detection by Goat anti - mouse IgG2b PE ) . A : CD52 positive cALL ( gate leukemic cells ) . B : CD52 negative pro T ALL ( gate leukemic cells ) . Mouse IgG2b HI186 Hu F, P
0.1 mg / €390.00
  Abnova Taiwan Corp.

CD52 / CAMPATH-1 antibody

CD52 / CAMPATH-1 Mouse IgG2b HI186 Hu F, P
100 reaction / €390.00
  Abnova Taiwan Corp.

CD52 / CAMPATH-1 antibody

CD52 / CAMPATH-1 Mouse IgG2b HI186 Hu F, P
100 reaction / €390.00
  Abnova Taiwan Corp.

CD52 / CAMPATH-1 antibody

CD52 / CAMPATH-1 Mouse IgG2b HI186 Hu F, P
100 reaction / €390.00
  Abnova Taiwan Corp.

CD52 / CAMPATH-1 antibody

Western blot analysis of CD52 expression in THP1 (A); mouse spleen (B); H9C2 (C) whole cell lysates. Rabbit Aff - Purified Hu, Ms, Rt WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

CD52 / CAMPATH-1 antibody

Western blot analysis of CD52 expression in THP1 (A); mouse spleen (B); H9C2 (C) whole cell lysates. Rabbit Aff - Purified Hu, Ms, Rt WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

CD52 / CAMPATH-1 antibody

Western blot analysis of CD52 expression in THP1 (A); mouse spleen (B); H9C2 (C) whole cell lysates. Rabbit Aff - Purified Hu, Ms, Rt WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

CD52 / CAMPATH-1 antibody

Flow Cytometry: CD52 Antibody (HI186) [NB500-311] - Fig. 1. Flow cytometry analysis of CD52 in patients suffering with Acute Lymphoblastic Leukemia (anti-human CD52 (HI186); detection by Goat anti-mouse IgG2b PE). Fig. 1A CD52 positive cALL (gate leukemic cells). Mouse IgG2b HI186 Aff - Purified Hu F, P
0.1 mg / €340.00
  Novus Biologicals Inc.

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