CD53 antibody

Principal name

CD53 antibody

Alternative names for CD53 antibody

Cell surface glycoprotein CD53, Tetraspanin-25, MOX44, TSPAN25, Leukocyte surface antigen CD53

SwissProt ID

P19397 (Human), P24485 (Rat), Q58DM3 (Bovin), Q61451 (Mouse)

Gene ID

963 (CD53), 24251 (Cd53), 12508

Available reactivities

Hu (Human), Rt (Rat)

Available hosts

Mouse

Available applications

Frozen Sections (C), Functional assay (FN), Immunoprecipitation (IP), Western blot / Immunoblot (WB), Flow Cytometry (F), Paraffin Sections (P), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of CD53 antibody

CD53 is a member of the tetraspan family of molecules, and is expressed by all leucocytes, but is absent from red cells and platelets.
Most of the tetraspan family of molecules are cell surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. CD53 is a cell surface glycoprotein that is known to complex with integrins. It contributes to the transduction of CD2 generated signals in T cells and natural killer cells and has been suggested to play a role in growth regulation. Familial deficiency of this gene has been linked to an immunodeficiency associated with recurrent infectious diseases caused by bacteria, fungi and viruses. CD53 is a glycoprotein of 32-40 kDa belonging to the tetraspans family (TM4SF). CD53 antigen is exclusivelly expressed on leucocytes (not present on platelets, red blood cells and non-hematopoietic cells). CD53 is important for signal transduction. CD53 cross-linking promotes activation of human B cells and rat macrophages.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CD53 antibody

CD53 Mouse IgG1 OX-44 Purified Rt C, F, IP, P
0.25 mg / €420.00
  Acris Antibodies GmbH

CD53 antibody

CD53 Mouse IgG1 OX-44 Purified Rt C, F, IP, P
0.1 mg / €260.00
  Acris Antibodies GmbH

CD53 antibody

CD53 Mouse IgG1 MEM-53 Azide Free Hu C, F, FN, IP, WB
0.1 mg / €210.00
  Acris Antibodies GmbH

CD53 antibody

Staining of human peripheral blood monocytes with MOUSE ANTI HUMAN CD53:FITC (SM1137F). Mouse IgG1 MEM-53 FITC Hu F
100 Tests / €390.00
  Acris Antibodies GmbH

CD53 antibody

CD53 Mouse IgG1 MEM-53 Low Endotoxin Hu C, F, FN, IP, WB
0.1 mg / €210.00
  Acris Antibodies GmbH

CD53 antibody

Spleen, Human: Formalin-Fixed, Paraffin-Embedded (FFPE) Mouse IgG1 MEM-53 Purified Hu C, F, IP, P, WB
0.2 mg / €430.00
  Acris Antibodies GmbH

CD53 antibody

CD53 Mouse IgG1 MEM-53 Purified Hu C, F, FN, IP, WB
0.1 mg / €210.00
  Acris Antibodies GmbH

CD53 antibody

CD53 Mouse IgG1 MEM-53 PE Hu F
100 Tests / €290.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

CD53 - human gene knockout kit via CRISPR

CD53 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

CD53 - human gene knockout kit via CRISPR

CD53 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

CD53 - human gene knockout kit via CRISPR

CD53 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Cd53 - mouse gene knockout kit via CRISPR

Cd53 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Cd53 - mouse gene knockout kit via CRISPR

Cd53 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Cd53 - mouse gene knockout kit via CRISPR

Cd53 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Cd53 - mouse gene knockout kit via CRISPR

Cd53 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

CD53 (transcript variant 2)

  Purified recombinant protein of Homo sapiens CD53 molecule (CD53), transcript variant 2  
CD53 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

CD53 overexpression lysate

CD53 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, CD53 (mGFP-tagged)-Human CD53 molecule (CD53), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, CD53 (mGFP-tagged)-Human CD53 molecule (CD53), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, CD53 (mGFP-tagged) - Human CD53 molecule (CD53), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, CD53 (mGFP-tagged) - Human CD53 molecule (CD53), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, CD53 (Myc-DDK-tagged)-Human CD53 molecule (CD53), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, CD53 (Myc-DDK-tagged)-Human CD53 molecule (CD53), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

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