CD62E / E-Selectin antibody

Principal name

CD62E / E-Selectin antibody

Alternative names for CD62E / E-Selectin antibody

SELE, ELAM1, LECAM2, Endothelial leukocyte adhesion molecule 1, Leukocyte-endothelial cell adhesion molecule 2, CD62 antigen-like family member E

SwissProt ID

P16581 (Human), P27113 (Rabit), P33730 (Canfa), P98105 (Rat), P98107 (Bovin), P98110 (Pig), Q00690 (Mouse), Q95LG1 (Horse)

Gene ID

6401 (SELE), 20339 (Sele), 25544

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Por (Porcine), Mky (Monkey), Chimp (Chimpanzee), Bab (Baboon)

Available hosts

Rabbit, Rat, Mouse, Sheep

Available applications

Immunoprecipitation (IP), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF), Functional assay (FN), Flow Cytometry (F), Frozen Sections (C), Enzyme Immunoassay (E), ELISA (detection) (E(detection)), EPair for Elisa (EPair), ELISA (capture) (E(capture)), Luminex (LMNX)

Background of CD62E / E-Selectin antibody

Endothelial Leukocyte Adhesion Molecule-1 belongs to the selectin family of adhesion molecules. Together with L-selectin and P-selectin, E-selectin mediates the initial interactions of leukocytes and platelets with endothelial cells. Molecular structure: The extracellular part of all selectins consists of an aminoterminal c-type lectin domain which specifically binds to carbohydrate ligands. This is followed by an EGF-like domain, and, in the case of E-selectin, by 6 short consensus repeats. The transmembrane portion of the molecule is followed by a short cytoplasmic tail. Selectins guide non-activated polymorphonuclear cells to the areas of inflammation in creating first, loose contacts with the endothelial layer. Together with P-selectin, E-selectin is expressed on cytokine-activated endothelial cells, and contributes to the adhesion of still resting leukocytes to the endothelium. This initial binding event is an essential prerequisite for the activation of the immune cells via different inflammatory mediators. In contrast to P-selectin, E-selectin is maximally expressed 2-4 hours after cell activation. Within the next 24-48 hours E-selectin is again eliminated from the cytoplasmic membrane by shedding into the circulation.

General readings

Vermot-Desroches C. et al, AS22.1 Leucocyte Typing Workshop VI, Kobe (1996)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CD62E / E-Selectin antibody

Western blot analysis of E-Selectin with Jurkat cell lysate  35 Rabbit IgG Aff - Purified Hu, Ms, Rt IP, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CD62E / E-Selectin antibody

Staining of TNF alpha-stimulated Human Umbilical Vein Endothelial Cells (HUVEC) with 0.5 ug of Mouse IgG1 kappa Isotype Control Purified (open histogram) or 0.5 ug of Anti-Human CD62E (E- Selectin) Purified (filled histogram) followed by F(ab')2 Anti-Mouse IgG PE .  Total viable cells were used for analysis. Mouse P2H3 Purified Hu F, IP, P
0.1 mg / €130.00
  OriGene Technologies, Inc.

CD62E / E-Selectin antibody

Predicted cell location: Cytoplasm. Positive control: Human ovarian and gastric cancer tissue . Recommended dilution: 1/50-200  The image on the left is immunohistochemistry of paraffin-embedded human ovarian cancer tissue using SELE antibody at dilution 1/40, on the right is treated with the fusion protein. (Original magnification:x 200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

CD62E / E-Selectin antibody

Predicted cell location: Cell membrane,Cytoplasm . Positive control: Human esophagus and lung cancer tissue . Recommended dilution: 1/50-200  The image on the left is immunohistochemistry of paraffin-embedded human esophagus cancer tissue using SELE antibody at dilution 1/30, on the right is treated with the fusion protein. (Original magnification:x 200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

CD62E / E-Selectin antibody

Western blot analysis of extracts of various cell lines, using SELE antibody. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CD62E / E-Selectin antibody

SELE ELISA with CL-37 Capture (TA600028) and CL2 Detection (TA700028) Antibodies. Substrate used: Recombinant Human SELE (TP321153) Mouse IgG1 OTICL-37 Purified Hu E, LMNX
0.1 mg / €325.00
  OriGene Technologies, Inc.

CD62E / E-Selectin antibody

SELE ELISA with CL-37 Capture (TA600028) and CL2 Detection (TA700028) Antibodies. Substrate used: Recombinant Human SELE (TP321153) Mouse IgG1 OTICL2 Purified Hu E, LMNX
50 µg / €345.00
  OriGene Technologies, Inc.

CD62E / E-Selectin antibody

CD62E / E-Selectin Rat IgG2a 4D10 FITC Hu F
0.5 mg / €420.00
  Acris Antibodies GmbH

CD62E / E-Selectin antibody

CD62E / E-Selectin Mouse IgG1 ENA2 Purified Hu, Mky C, E, FN
0.1 mg / €340.00
  Acris Antibodies GmbH

CD62E / E-Selectin antibody

CD62E / E-Selectin Mouse IgG1 ENA1 Purified Hu, Mky C, E, FN, IP
0.1 mg / €340.00
  Acris Antibodies GmbH

CD62E / E-Selectin antibody

A typical staining pattern with the B-P7 monoclonal antibody of ELAM-1 transfected CHO cell line Mouse IgG1 B-P7 Azide Free Hu F
0.2 mg / €270.00
  Acris Antibodies GmbH

CD62E / E-Selectin antibody

A typical staining pattern with the B-P7 monoclonal antibody of ELAM-1 transfected CHO cell line Mouse IgG1 B-P7 Purified Hu F
2ml (200 Tests) / €250.00
  Acris Antibodies GmbH

CD62E / E-Selectin antibody

CD62E / E-Selectin Mouse IgG1 B-P7 Azide Free Hu E(capture)
1 mg / €790.00
  Acris Antibodies GmbH

CD62E / E-Selectin antibody

CD62E / E-Selectin Mouse IgG1 B-S3 Biotin Hu E(detection)
0.1 mg / €460.00
  Acris Antibodies GmbH

CD62E / E-Selectin F(ab')2 antibody

CD62E / E-Selectin Mouse IgG1 ENA2 Liquid Bab, Chimp, Hu, Mky C, E, FN
1 ml / €620.00
  Acris Antibodies GmbH

CD62E / E-Selectin antibody

CD62E / E-Selectin Mouse IgG1 ENA1 Biotin Hu C
0.5 ml / €370.00
  Acris Antibodies GmbH

CD62E / E-Selectin antibody

CD62E / E-Selectin Mouse IgG1 ENA1 Liquid Hu C
1 ml / €370.00
  Acris Antibodies GmbH

CD62E / E-Selectin control peptide

CD62E / E-Selectin Purified
50 µg / €190.00
  Acris Antibodies GmbH

CD62E / E-Selectin antibody

CD62E / E-Selectin Rabbit IgG Biotin Hu, Mky C, E, WB
50 µg / €450.00
  Acris Antibodies GmbH

CD62E / E-Selectin (+CD62P) antibody

Staining of Thrombin activated Human peripheral blood platelets with Mouse anti Human CD62E/CD62P antibody Mouse IgG1 1.2B6 Purified Hu, Por C, E, F, ICC/IF, WB
0.2 mg / €480.00
  Acris Antibodies GmbH

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