CD62L / L-Selectin antibody

Principal name

CD62L / L-Selectin antibody

Alternative names for CD62L / L-Selectin antibody

SELL, LNHR, LYAM1, Leu-8, TQ1, gp90-MEL, LECAM1, LAM-1, Lymph node homing receptor, Leukocyte adhesion molecule 1, Leukocyte surface antigen Leu-8, Leukocyte-endothelial cell adhesion molecule 1, CD62 antigen-like family member L

SwissProt ID

P14151 (Human), P18337 (Mouse), P30836 (Rat), P98131 (Bovin)

Gene ID

6402 (SELL), 20343 (Sell), 281485

Available reactivities

Ms (Mouse), Bov (Bovine), Hu (Human), Mky (Monkey), Can (Canine), Rt (Rat)

Available hosts

Rat, Mouse, Rabbit, Sheep

Available applications

Frozen Sections (C), Functional assay (FN), Immunoprecipitation (IP), Flow Cytometry (F), ELISA (detection) (E(detection)), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P)

Background of CD62L / L-Selectin antibody

The Human CD62L is a 74-95 kDa glycoprotein member of the selectin family of adhesion receptors. Human CD62L (L Selectin) is comprised of an aminoterminal C type lectin binding domain, an epidermal growth factor like domain, two short consensus repeat (SCR) sequences homologous to those found in complement binding proteins, a short spacer region, a transmembrane region and a short cytoplasmic region. Human CD62L is constitutively expressed on all classes of leukocytes including lymphocytes (except a substantial population of memory T cells), monocytes and polymorphonuclear cells. It is expressed on bone marrow myeloid progenitor cells, erythroid precursor cells and some thymocytes. It is preferentially localized to the tips of lymphocytes and polymorphonuclear cells microvilli. Bioactive soluble L Selectin derived from lymphocytes and neutrophils is present in normal and pathological biological fluids.

General readings

1. Fink, P., W. Gallatin, R. Reichert, et al. 1985. Homing receptor-bearing thymocytes, an immunocomponent cortical subpopulation. Nature 313: 233-235
2. Gallatin,W.M., I.L. Weissman., E.C. Butcher 1983. A cell surface molecule involved in organ specific homing of lymphocytes. Nature 304:30-34
3. Lewinsohn, D.M., R.F. Bargatze, E.C. Butcher 1987. Leukocyteendothelial cell recognition: evidence of a common molecular mechanism
shared by neutrophils, lymphocytes and other leukocytes. J.Immunology 138:4313-4321
4. Reichert, R., M. Gallitin, E. Butcher, et al.. 1984. A homing receptorbearing cortical thymocyte subset: Implications for thymus cell migration and the nature of cortisone-resisatant thymocytes. Cell 38: 89-99
5. Siegelman, M., I.C. Cheng, I.L. Weissman, et al. 1990. The mouse lymph node homing receptor is identical with the lymphocyte cell surface receptor Ly-22: Role of the EGF domain in endothelial binding. Cell 61: 611-622
6. Jalkanen, S., R.F. Bargatze, J. Toyos, et al. 1987. Lymphocyte Recognition of High Endothelium: Antibodies to Distinct Epitopes of an 85-95-kD Glycoprotein Antigen Differentially Inhibit Lymphocyte Binding to Lymph Node, Mucosal, or Synovial Endothelial Cell. J. of Cell Biol. 105: 983-990

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CD62L / L-Selectin antibody

  Rabbit polyclonal anti-L-Selectin/CD62L antibody  
Western blot analysis of L-Selectin expression in Jurkat cell lysate. Rabbit Aff - Purified Hu, Ms, Rt IP, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CD62L / L-Selectin antibody

  Mouse Anti-Human CD62L (L-Selectin) Purified (100 ug)  
Staining of normal human peripheral blood cells with 0.5 ug of Mouse IgG1 kappa Isotype Control Purified (open histogram) or 0.5 ug of Anti-Human CD62P (P-Selectin) Purified (filled histogram) followed by  Anti-Mouse IgG FITC .  Cells in the lymphocyte gate were used for analysis. Mouse DREG-56 (DREG56) Purified Hu F, P, WB
0.1 mg / €120.00
  OriGene Technologies, Inc.

CD62L / L-Selectin antibody

  Rat Anti-Mouse CD62L (L-Selectin) Purified (50 ug)  
Staining of BALB/c splenocytes with 0.25 ug of Rat IgG2a kappa Isotype Control Purifed (open histogram) or 0.25 ug of Anti-Mouse CD62L (L-Selectin) Purified (filled histogram) followed by Anti-Rat IgG FITC .  Cells in the lymphocyte gate were used for analysis. Rat MEL-14 Purified Ms F, IP, P
50 µg / €120.00
  OriGene Technologies, Inc.

CD62L / L-Selectin (C-term) antibody

  Rabbit polyclonal SELL Antibody (C-term)  
Western blot analysis of SELL Antibody (C-term) (Cat. #TA324887) in Jurkat cell line lysates (35ug/lane).SELL (arrow) was detected using the purified Pab. Rabbit Hu WB
0.4 ml / €325.00
  OriGene Technologies, Inc.

CD62L / L-Selectin antibody

  SELL Rabbit Polyclonal Antibody  
Western blot analysis of extracts of various cell lines, using SELL antibody. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CD62L / L-Selectin antibody

  Mouse Monoclonal anti-CD62L Antibody  
CD62L (DREG 56.6) staining of human peripheral blood lymphocytes analyzed by flow cytometry. Mouse IgG1 DREG 56.6 Purified Hu F
100 µl / €325.00
  OriGene Technologies, Inc.

CD62L / L-Selectin antibody

  Rat Monoclonal anti-CD62L Antibody  
C57BL/6 mouse splenocytes stained with purified MEL-14, followed by anti-rat IgG FITC Rat MEL-14 Purified Ms F, IP, P
0.5 mg / €325.00
  OriGene Technologies, Inc.

CD62L / L-Selectin antibody

  Mouse Monoclonal anti-CD62L Antibody  
Human peripheral blood lymphocytes stained with purified DREG-56, followed by anti-mouse IgGs FITC Mouse DREG-56 Purified Hu F, P, WB
0.1 mg / €248.00
  OriGene Technologies, Inc.

CD62L / L-Selectin antibody

  Rabbit Polyclonal L-selectin Antibody  
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SELL (RC216982, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SELL. Rabbit IgG Purified Hu E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CD62L / L-Selectin antibody

Surface staining of human peripheral blood cells with anti-CD62L (LT-TD180) purified, GAM-APC. Mouse IgG1 LT-TD180 APC Hu F
100 Tests / €290.00
  Acris Antibodies GmbH

CD62L / L-Selectin antibody

Surface staining of human peripheral blood cells with anti-CD62L (LT-TD180) APC. Mouse IgG1 LT-TD180 FITC Hu F
100 Tests / €260.00
  Acris Antibodies GmbH

CD62L / L-Selectin antibody

Surface staining of human peripheral blood cells with anti-CD62L (LT-TD180) APC. Mouse IgG1 LT-TD180 Purified Hu F
0.1 mg / €210.00
  Acris Antibodies GmbH

CD62L / L-Selectin antibody

Surface staining of human peripheral blood cells with anti-CD62L (LT-TD180) APC. Mouse IgG1 LT-TD180 PE Hu F
100 Tests / €290.00
  Acris Antibodies GmbH

CD62L / L-Selectin antibody

CD62L / L-Selectin Mouse IgG2a 1H3 FITC Hu F
100 Tests / €270.00
  Acris Antibodies GmbH

CD62L / L-Selectin antibody

CD62L / L-Selectin Mouse IgG2a 1H3 Purified Hu F
0.1 mg / €250.00
  Acris Antibodies GmbH

CD62L / L-Selectin antibody

CD62L / L-Selectin Mouse IgG2a 1H3 PE Hu F
100 Tests / €300.00
  Acris Antibodies GmbH

CD62L / L-Selectin antibody

Surface staining of CD62L in human peripheral blood with anti-CD62L (DREG56) Alexa Fluor 700. Mouse IgG1 DREG56 FITC Hu F
100 Tests / €260.00
  Acris Antibodies GmbH

CD62L / L-Selectin antibody

Surface staining of CD62L in human peripheral blood with anti-CD62L (DREG56) Alexa Fluor 700. Mouse IgG1 DREG56 Low Endotoxin Hu C, F, FN, IP, WB
0.1 mg / €210.00
  Acris Antibodies GmbH

CD62L / L-Selectin antibody

Surface staining of CD62L in human peripheral blood with anti-CD62L (DREG56) Alexa Fluor 700. Mouse IgG1 DREG56 Purified Hu C, F, FN, IP, WB
0.1 mg / €210.00
  Acris Antibodies GmbH

CD62L / L-Selectin antibody

A typical staining pattern with the B-S13 monoclonal antibody of lymphocytes Mouse IgG1 B-S13 Azide Free Hu E, F
0.2 mg / €270.00
  Acris Antibodies GmbH

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