CD62P / P-Selectin antibody

Principal name

CD62P / P-Selectin antibody

Alternative names for CD62P / P-Selectin antibody

SELP, GMRP, GRMP, PADGEM, GMP-140, LECAM3, Granule membrane protein 140, Leukocyte-endothelial cell adhesion molecule 3, CD62 antigen-like family member P

SwissProt ID

P16109 (Human), P42201 (Bovin), P98106 (Rat), P98109 (Sheep), Q01102 (Mouse)

Gene ID

6403 (SELP), 20344 (Selp)

Available reactivities

Hu (Human), Mky (Monkey), Bov (Bovine), Eq (Equine), Fe (Feline), Gt (Goat), Ms (Mouse), Rt (Rat), Sh (Sheep), Por (Porcine), Prim (Primate)

Available hosts

Mouse, Chicken, Rabbit, Rat

Available applications

Frozen Sections (C), Immunoprecipitation (IP), Western blot / Immunoblot (WB), Flow Cytometry (F), Paraffin Sections (P), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Functional assay (FN), Enzyme Immunoassay (E)

Background of CD62P / P-Selectin antibody

P-selectin (Plasma Selectin), a member of the Selectin family of cell adhesion molecules, is important in the recruitment of leukocytes to the site of injury during inflammation. Following stimulation with thrombin, histamine, PMA or peroxides P Selectin is released from granules within endothelial cells and is then translocated to the cell surface. P-Selectin binds to P-selectin glycoprotein ligand1 (PSGL1) present on myeloid cells, neutrophils, monocytes and lymphocytes. P-Selectin is involved in the initial interaction of circulating leucocytes with the endothelium at sites of inflammation. Acting with L-Selectin and E-selectin, P-Selectin causes the extravasation of the white blood cell through the blood vessel wall into the extracellular matrix tissue. This is a HCX protein. HCX Expression System Details HCX proteins mimic the proteins in the human body because they are expressed from human, rather than animal, insect or bacterial cells. This process gives them human post-translational modifications. Recombinant DNA techniques allow a human protein with the correct amino acid sequence to be expressed in a non-human cell line. However, non-human cells lack the appropriate cellular machinery, such as specific glycosyltransferases, necessary to produce the correct human post-translational modifications of a protein. An extreme example is seen in E. coli cells, which produce recombinant proteins with no glycosylation, as the above figure illustrates. Rodent and yeast cells are able to glycosylate proteins, but they are still different from glycosylation in human cells. Expression System Resultant Proteins Human (e.g. K562, HEK293) Correct amino acid sequence Human post-translational modifications Rodent (e.g. CHO, NSO) Correct amino acid sequence Some natural glycosylation - not human-like Yeast (e.g. Pichia) Correct amino acid sequence Some natural glycosylation - not human-like E.Coli Correct amino acid sequence No PTMs Although there have been significant attempts to make non-human cell derived cytokines more human-like, there is a growing awareness that in many instances, particularly in therapeutics, cytokines should mimic those found in the body as closely as possible.

  1. Quick-Filters:
  2. Cited (2)

Items 1 to 20 of 75 total

per page
Page:
  1. 1
  2. 2
  3. 3
  4. 4

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CD62P / P-Selectin antibody

Staining of thrombin activated human peripheral blood platelets with Mouse Anti-Human CD62P Antibody FITC conjugated (SM1150F/FT). Mouse IgG1 AK-6 FITC Hu, Mky F
0.1 mg / €410.00
  Acris Antibodies GmbH

CD62P / P-Selectin antibody

Staining of thrombin activated human peripheral blood platelets with Mouse Anti-Human CD62P Antibody FITC conjugated (SM1150F/FT). Mouse IgG1 AK-6 FITC Hu, Mky F
25 µg / €190.00
  Acris Antibodies GmbH

CD62P / P-Selectin antibody

Western blot analysis of P- Selectin expression in Jurkat cell lysate. Rabbit Purified Hu, Ms, Rt P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CD62P / P-Selectin antibody

Staining of thrombin-activated human peripheral blood platelets with 0.5 ug of Mouse IgG1 kappa Isotype Control Purifed (open histogram) or 0.5 ug of Anti-Human CD62P (P-Selectin) Purified (filled histogram) followed by Anti-Mouse IgG FITC .  Total viable cells were used for analysis. Mouse AK-4 Purified Hu F, P
0.1 mg / €120.00
  OriGene Technologies, Inc.

CD62P / P-Selectin antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SELP (RC209822, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SELP. Rabbit IgG Purified Hu E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CD62P / P-Selectin antibody

CD62P / P-Selectin Mouse IgG1 HI62P Aff - Purified Hu F, WB
0.1 mg / €220.00
  Acris Antibodies GmbH

CD62P / P-Selectin antibody

Immunohistochemistry: AM05567PU-N SELP antibody staining of Formalin-Fixed, Paraffin-Embedded Human Tonsil followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen. Mouse IgG1 Psel.KO.2.5 Purified Hu, Por, Sh F, IP, P
0.2 mg / €430.00
  Acris Antibodies GmbH

CD62P / P-Selectin antibody

Staining of thrombin activated peripheral blood platelets with mouse anti human CD62P Antibody -RPE (Cat.-No AM05567RP-N) Mouse IgG1 Psel.KO.2.5 PE Hu, Por F
100 Tests / €470.00
  Acris Antibodies GmbH

CD62P / P-Selectin antibody

CD62P / P-Selectin Mouse IgG1 AK4 APC Hu, Prim F
100 Tests / €290.00
  Acris Antibodies GmbH

CD62P / P-Selectin antibody

CD62P / P-Selectin Mouse IgG1 AK4 Biotin Hu, Prim F
0.1 mg / €260.00
  Acris Antibodies GmbH

CD62P / P-Selectin antibody

CD62P / P-Selectin Mouse IgG1 AK4 FITC Hu, Prim F
100 Tests / €260.00
  Acris Antibodies GmbH

CD62P / P-Selectin antibody

CD62P / P-Selectin Mouse IgG1 AK4 Low Endotoxin Hu, Prim
0.1 mg / €210.00
  Acris Antibodies GmbH

CD62P / P-Selectin antibody

CD62P / P-Selectin Mouse IgG1 AK4 Aff - Purified Hu, Prim F, FN, ICC/IF, IP, WB
0.1 mg / €210.00
  Acris Antibodies GmbH

CD62P / P-Selectin antibody

CD62P / P-Selectin Mouse IgG1 AK4 PE Hu, Prim F
100 Tests / €290.00
  Acris Antibodies GmbH

CD62P / P-Selectin antibody

CD62P / P-Selectin Mouse IgG2b B-G43 Azide Free Hu
0.2 mg / €270.00
  Acris Antibodies GmbH

CD62P / P-Selectin antibody

A typical staining pattern with the B-F46 monoclonal antibody of platelets. Mouse IgG1 B-F46 Azide Free Hu
0.2 mg / €270.00
  Acris Antibodies GmbH

CD62P / P-Selectin antibody

A typical staining pattern with the B-F46 monoclonal antibody of platelets. Mouse IgG1 B-F46 Purified Hu F
2ml (200T) / €250.00
  Acris Antibodies GmbH

CD62P / P-Selectin antibody

CD62P / P-Selectin Mouse IgG1 CRC81 Purified Hu ICC/IF, WB
1 ml / €350.00
  Acris Antibodies GmbH

CD62P / P-Selectin antibody

CD62P / P-Selectin Mouse IgG1 CRC81 PE Hu
0.5 ml / €450.00
  Acris Antibodies GmbH

CD62P / P-Selectin antibody

Flow Cytometry: SM1150A CD62P antibody staining of Thrombin activated Human platelets. Mouse IgG1 AK-6 Azide Free Hu, Mky C, F, P, WB
1 mg / €790.00
  Acris Antibodies GmbH

Items 1 to 20 of 75 total

per page
Page:
  1. 1
  2. 2
  3. 3
  4. 4
  • LinkedIn