CD68 antibody

Principal name

CD68 antibody

Alternative names for CD68 antibody

Gp110, Macrosialin, Macrophage marker

SwissProt ID

P31996 (Mouse), P34810 (Human), Q4FZY1 (Rat)

Gene ID

968 (CD68), 287435 (Cd68), 12514

Available reactivities

Hu (Human), Bov (Bovine), Rt (Rat), Ms (Mouse), GP (Guinea Pig), Mky (Monkey), Fe (Feline), Por (Porcine), Can (Canine)

Available hosts

Mouse, Rat, Rabbit

Available applications

Paraffin Sections (P), Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Radioimmunoassay (R), Western blot / Immunoblot (WB), Flow Cytometry (F), Enzyme Immunoassay (E), ELISA (detection) (E(detection))

Selected product citations ‐ of BM4000

1. Schneider R, Meusel M, Renker S, Bauer C, Holzinger H, Roeder M, et al. Low-dose indomethacin after ischemic acute kidney injury prevents downregulation of Oat1/3 and improves renal outcome. Am J Physiol Renal Physiol. 2009 Dec;297(6):F1614-21. doi: 10.1152/ajprenal.00268.2009. Epub 2009 Sep 30. PubMed PMID: 19794109.
2. Meyer J, Cunea A, Sonntag-Bensch D, Welker P, Licha K, Holz FG, et al. In vivo imaging of a new indocyanine green micelle formulation in an animal model of laser-induced choroidal neovascularization. Invest Ophthalmol Vis Sci. 2014 Sep 4;55(10):6204-12. doi: 10.1167/iovs.13-13617. PubMed PMID: 25190666.
3. Meyer, JH;Cunea, A;Licha, K;Welker, P;Sonntag-Bensch, D;Wafula, P;Dernedde, J;Fimmers, R;Holz, FG;Schmitz-Valckenberg, S. In Vivo Imaging of Fluorescent Probes Linked to Antibodies Against Human and Rat Vascular Endothelial Growth Factor. Invest. Ophthalmol. Vis. Sci. 2016, 759-70, 57. PubMed PMID: 226927569. 
4.Tuleta, I;Stöckigt, F;Juergens, UR;Pizarro, C;Schrickel, JW;Kristiansen, G;Nickenig, G;Skowasch, D. Intermittent Hypoxia Contributes to the Lung Damage by Increased Oxidative Stress, Inflammation, and Disbalance in Protease/Antiprotease System. Lung 2016. PubMed PMID: 27738828.

Background of CD68 antibody

CD68, cluster of differentiation, is a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. CD68 is a member of a family of hematopoietic mucin-like molecules that includes leukosialin/CD43 and stem cell antigen CD34. The CD68 gene is mapped to 17p13.1. Immunohistochemistry can be used to identify the presence of CD68, which is found in the cytoplasmic granules of a range of different blood cells. It is particularly useful as a marker for the various cells of the macrophage lineage, including monocytes, histiocytes, giant cells, Kupffer cells, and osteoclasts. This allows it to be used to distinguish diseases of otherwise similar appearance, such as the monocyte/macrophage and lymphoid forms of leukaemia (the latter being CD68 negative). Its presence in macrophages also makes it useful in diagnosing conditions related to proliferation or abnormality of these cells, such as malignant histiocytosis, histiocytic lymphoma, and Gaucher's disease.

General readings

Holness CL., et al. (1993) Blood. 81(6):1607-13.Shun CT., et al. (2009) J Infect Dis. 199:1488-1496.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CD68 antibody

Figure 1. Staining of rat liver, with induced hepatocellular damage, with Mouse anti Rat CD68 antibody Cat.-No BM4000 Mouse IgG1 ED1 Purified Bov, Rt C, F, ICC/IF, IP, P, R, WB
0.25 mg / €620.00
  Acris Antibodies GmbH

CD68 antibody

Figure 1. Staining of rat liver, with induced hepatocellular damage, with Mouse anti Rat CD68 antibody Cat.-No BM4000 Mouse IgG1 ED1 Purified Bov, Rt C, F, ICC/IF, IP, P, R, WB

Regular Price: 0.1 mg / €370.00

Special Price: 0.1 mg / €259.00

  Acris Antibodies GmbH

CD68 antibody

Staining of FFPE Mouse spleen with Rat anti Mouse CD68 Antibody Cat.-No SM1550PS (Clone FA-11) at 2 µg/ml. Antibody positive in cytoplasm of macrophages. Rat IgG2a FA-11 Purified Ms C, F, ICC/IF, IP, P, WB
0.25 mg / €550.00
  Acris Antibodies GmbH

CD68 antibody

Staining of FFPE Mouse spleen with Rat anti Mouse CD68 Antibody Cat.-No SM1550PS (Clone FA-11) at 2 µg/ml. Antibody positive in cytoplasm of macrophages. Rat IgG2a FA-11 Purified Ms C, F, ICC/IF, IP, P, WB
0.1 mg / €430.00
  Acris Antibodies GmbH

CD68 antibody

CD68 Mouse IgG1 ED1 Biotin Bov, Rt C, F
100 Tests / €530.00
  Acris Antibodies GmbH

CD68 antibody

Staining of rat peritoneal macrophages cells with Mouse Permeabilised Anti Rat CD68 antibody FITC conjugated (BM4000F). Mouse IgG1 ED1 FITC Bov, Rt F
0.1 mg / €670.00
  Acris Antibodies GmbH

CD68 antibody

Staining of rat peritoneal macrophages cells with Mouse Anti RAT CD68 antibody RPE conjugated (BM4000R). Mouse IgG1 ED1 PE Bov, Rt F
100 Tests / €670.00
  Acris Antibodies GmbH

CD68 antibody

CD68 Rat IgG2a FA-11 Azide Free Ms C, F, IP, WB

Regular Price: 0.2 mg / €370.00

Special Price: 0.2 mg / €259.00

  Acris Antibodies GmbH

CD68 antibody

Staining of mouse peritoneal macrophages cells with Rat Anti Mouse CD68 antibody -Biotin (Cat.-No SM1550B). Rat IgG2a FA-11 Biotin Ms F
0.1 mg / €530.00
  Acris Antibodies GmbH

CD68 antibody

CD68 Rat IgG2a FA-11 FITC Ms F
50 µg / €240.00
  Acris Antibodies GmbH

CD68 antibody

Staining of Mouse peritoneal macrophages with Rat anti Mouse CD68 antibody -RPE (SM1550R) following permeablisation with Leucoperm. Rat IgG2a FA-11 PE Ms F
100 Tests / €410.00
  Acris Antibodies GmbH

CD68 antibody

  CD68 mouse monoclonal antibody,clone UMAB150  
CD68 Mouse IgG1 UMAB150 Purified Hu P, WB
0.1 ml / €468.00
  OriGene Technologies, Inc.

UltraMAB

CD68 antibody

  CD68 mouse monoclonal antibody,clone UMAB150  
CD68 Mouse IgG1 UMAB150 Purified Hu P, WB
30 µl / €140.00
  OriGene Technologies, Inc.

UltraMAB

CD68 antibody

  CD68 mouse monoclonal antibody, clone OTI3B6 (formerly 3B6)  
Immunohistochemical staining of paraffin-embedded Human bladder tissue within the normal limits using anti-CD68 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA802949) Mouse IgG1 OTI3B6 Purified Hu F, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CD68 antibody

  CD68 mouse monoclonal antibody, clone OTI4G1  
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-CD68 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA802952) Mouse IgG1 OTI4G1 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CD68 antibody

  CD68 mouse monoclonal antibody, clone OTI8A4 (formerly 8A4)  
Immunohistochemical staining of paraffin-embedded Human liver tissue within the normal limits using anti-CD68 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA802955) Mouse IgG2b OTI8A4 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CD68 antibody

  CD68 mouse monoclonal antibody, clone OTI7D3 (formerly 7D3)  
Immunohistochemical staining of paraffin-embedded Human colon tissue within the normal limits using anti-CD68 mouse monoclonal antibody. (TA803041; heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min) Mouse IgG2b OTI7D3 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CD68 antibody

  CD68 mouse monoclonal antibody, clone OTI12C5 (formerly 12C5)  
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-CD68 mouse monoclonal antibody. (TA803067) Dilution: 1:150 Mouse IgG1 OTI12C5 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CD68 antibody

  CD68 mouse monoclonal antibody, clone OTI1E6 (formerly 1E6)  
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-CD68 mouse monoclonal antibody. (TA803288) Dilution: 1:150 Mouse IgG2a OTI1E6 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CD68 antibody

Formalin-Fixed, Paraffin-Embedded Human tonsil (20X) stained with CD68 Antibody Cat.-No AM50195PU (Clone SPM130). Mouse IgG1 SPM130 Purified Fe, Hu, Mky, Ms, Rt C, F, ICC/IF, IP, P, WB
0.2 mg / €410.00
  Acris Antibodies GmbH

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