CD77 Synthase / A4GALT antibody

Principal name

CD77 Synthase / A4GALT antibody

Alternative names for CD77 Synthase / A4GALT antibody

A14GALT, A4GALT1, Gb3 synthase, P1/Pk synthase, Alpha4Gal-T1, Globotriaosylceramide synthase, Lactosylceramide 4-alpha-galactosyltransferase, Alpha-1,4-galactosyltransferase, UDP-galactose:beta-D-galactosyl-beta1-R 4-alpha-D-galactosyltransferase, Alpha-1,4-N-acetylglucosaminyltransferase

SwissProt ID

Q67BJ4 (Mouse), Q9JI93 (Rat), Q9NPC4 (Human)

Gene ID

53947 (A4GALT)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), GP (Guinea Pig), Rb (Rabbit)

Available hosts

Mouse, Rabbit, Rat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of CD77 Synthase / A4GALT antibody

Necessary for the biosynthesis of the Pk antigen of blood histogroup P. Catalyzes the transfer of galactose to lactosylceramide and galactosylceramide. Necessary for the synthesis of the receptor for bacterial verotoxins.Expression of CD77, also called Gb3, sensitizes a cell to verotoxins, causing cellular injury that can lead to disease. Therefore, the complex regulation of CD77 biosynthesis and the activity of the enzymes involved, such as CD77 synthase, can be studied by compared gene expression between toxin-sensitive and insensitive tissues and cell lines. The highest tissue expression of CD77 synthase occurs in the kidney, mesenteric lymph node, spleen, and brain. Burkitt leukemia cells express very high levels of CD77 as well as CD77 synthase, and are sensitive to verotoxin induced apoptosis. These megakaryoblasts then never mature, leading to the arrest of platelet generation in the bone marrow, which may cause thrombocytopenia, a symptom associated with various hemorrhagic conditions.

13 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CD77 Synthase / A4GALT antibody

WB Suggested Anti-A4GALT Antibody Titration: 0.2-1 ug/ml; Positive Control: THP-1 cell lysate Rabbit IgG Purified Bov, Can, GP, Hu, Ms, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

CD77 Synthase / A4GALT antibody

WB Suggested Anti-A4GALT Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 312500; Positive Control: HT1080 cell lysate Rabbit IgG Purified Bov, Can, GP, Hu, Ms, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

CD77 Synthase / A4GALT (N-term) antibody

A4GALT Antibody (N-term) (Cat. #AP50008PU-N) western blot analysis in 293 cell line lysates (35 µg/lane).This demonstrates the A4GALT antibody detected the A4GALT protein (arrow) Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CD77 Synthase / A4GALT antibody

CD77 Synthase / A4GALT Mouse IgG2a 3E12 Purified Hu E
50 µg / €370.00
  Abnova Taiwan Corp.

CD77 Synthase / A4GALT antibody

CD77 Synthase / A4GALT Mouse IgG2a 3E12 Ascites Hu E
0.2 ml / €370.00
  Abnova Taiwan Corp.

CD77 Synthase / A4GALT antibody

Human THP-1; WB Suggested Anti-A4GALT Antibody Titration: 0.2-1 ug/ml. Positive Control: THP-1 cell lysate; A4GALT antibody - middle region (ARP47302_P050) in Human THP-1 cells using Western Blot Rabbit Aff - Purified Hu, Ms, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

CD77 Synthase / A4GALT antibody

Human HT1080; WB Suggested Anti-A4GALT Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:312500. Positive Control: HT1080 cell lysate; A4GALT antibody - middle region (ARP47303_P050) in Human HT1080 cells using Western Blot Rabbit Aff - Purified Hu, Ms, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

CD77 Synthase / A4GALT antibody

Western Blot: CD77 Synthase Antibody [NBP1-62583] - This Anti-A4GALT antibody was used in Western Blot of THP-1       tissue lysate at a concentration of 1ug/ml. Rabbit Aff - Purified Hu, Ms, Rt WB
50 µg / €440.00
  Novus Biologicals Inc.

CD77 Synthase / A4GALT antibody

CD77 Synthase / A4GALT Rabbit Aff - Purified Hu, Ms, Rt WB
50 µg / €440.00
  Novus Biologicals Inc.

CD77 Synthase / A4GALT antibody

Immunohistochemistry-Paraffin: CD77 Synthase Antibody [NBP1-90824] - Immunohistochemical staining of human testis shows nuclear, cytoplasmic positivity in both cells in seminiferus ducts and leydig cells . Rabbit Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

CD77 Synthase / A4GALT

CD77 Synthase / A4GALT Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

CD77 Synthase / A4GALT

CD77 Synthase / A4GALT Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

A4GALT overexpression lysate

A4GALT overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

13 Item(s)

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