CD79b antibody

Principal name

CD79b antibody

Alternative names for CD79b antibody

B29, IGB, B-Cell marker, B-cell antigen receptor complex-associated protein beta-chain, B-cell-specific glycoprotein B29, Immunoglobulin-associated B29 protein

SwissProt ID

P15530 (Mouse), P40259 (Human)

Gene ID

15985 (Cd79b), 974 (CD79B)

Available reactivities

Ms (Mouse), Can (Canine), Hu (Human), Por (Porcine), Rt (Rat)

Available hosts

Hamster, Rat, Mouse, Rabbit

Available applications

Flow Cytometry (F), Frozen Sections (C), Immunoprecipitation (IP), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), ELISA (detection) (E(detection)), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of CD79b antibody

The B lymphocyte antigen receptor is a multimeric complex that includes the antigen-specific component, surface immunoglobulin (Ig). Surface Ig non-covalently associates with two other proteins, Ig-alpha and Ig-beta, which are necessary for expression and function of the B-cell antigen receptor. This gene encodes the Ig-beta protein of the B-cell antigen component. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq]. Transcript Variant: This variant (1) uses an alternate in-frame splice site in the 5' coding region, compared to variant 3. The encoded isoform (1) is shorter compared to isoform 3, but has identical N- and C- termini. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

General readings

1. Gong S, Nussenzweig MC: Regulation of an early developmental checkpoint in the B cell pathway by Ig beta. Science. 1996 Apr 19;272(5260):411-4.
2. Teh YM, Neuberger MS: The immunoglobulin (Ig)alpha and Igbeta cytoplasmic domains are independently sufficient to signal B cell maturation and activation in transgenic mice. J Exp Med. 1997 May 19;185(10):1753-8.
3. Nagata K, Nakamura T, Kitamura F, Kuramochi S, Taki S, Campbell KS, Karasuyama H: The Ig alpha/Igbeta heterodimer on mu-negative proB cells is competent for transducing signals to induce early B cell differentiation. Immunity. 1997 Oct;7(4):559-70.
4. Kouro T, Nagata K, Takaki S, Nisitani S, Hirano M, Wahl MI, Witte ON, Karasuyama H, Takatsu K: Bruton's tyrosine kinase is required for signaling the CD79b-mediated pro-B to pre-B cell transition. Int Immunol. 2001 Apr;13(4):485-93.
5. Fuentes-Panan? EM, Bannish G, Shah N, Monroe J.G.: Basal Igalpha/Igbeta signals trigger the coordinated initiation of pre-B cell antigen receptor-dependent processes. J Immunol. 2004 Jul 15;173(2):1000-11.
6. Fuentes-Panan? EM, Bannish G, van der Voort D, King LB, Monroe J.G.: Ig alpha/Ig beta complexes generate signals for B cell development independent of selective plasma membrane compartmentalization. J Immunol. 2005 Feb 1;174(3):1245-52.
7. Koyama M, Ishihara K, Karasuyama H, Cordell JL, Iwamoto A, Nakamura T: CD79 alpha/CD79 beta heterodimers are expressed on pro-B cell surfaces without associated mu heavy chain. Int Immunol. 1997 Nov;9(11):1767-72.
8. Maki K, Nagata K, Kitamura F, Takemori T, Karasuyama H: Immunoglobulin beta signaling regulates locus accessibility for ordered immunoglobulin gene rearrangements. J Exp Med. 2000 Apr 17;191(8):1333-40.
9. Li Y, Chen F, Putt M, Koo YK, Madaio M, Cambier JC, Cohen PL, Eisenberg RA: B cell depletion with anti-CD79 mAbs ameliorates autoimmune disease in MRL/lpr mice. J Immunol. 2008 Sep 1;181(5):2961-72.
10. Aiba Y, Kameyama M, Yamazaki T, Tedder TF, Kurosaki T: Regulation of B-cell
development by BCAP and CD19 through their binding to phosphoinositide 3-kinase. Blood. 2008 Feb 1;111(3):1497-503.
12. Kouro T, Nagata K, Takaki S, Nisitani S, Hirano M, Wahl MI, Witte ON, Karasuyama H, Takatsu K: Bruton's tyrosine kinase is required for signaling the CD79b-mediated pro-B to pre-B cell transition. Int Immunol. 2001 Apr;13(4):485-93.,

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CD79b antibody

Predicted band size: 26 kDa . Positive control: Mouse liver tissue lysate. Recommended dilution: 1/500-2000. (Gel: 10%SDS-PAGEe Lysate: 40 ug Primary antibody: 1/500 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute) Rabbit IgG Purified Hu, Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CD79b antibody

Western blot analysis of extracts of mouse liver tissue cell line, using CD79B antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

CD79b antibody

CD79b Hamster IgG HM79-12 Biotin Ms F
0.5 mg / €410.00
  Acris Antibodies GmbH

CD79b antibody

CD79b Hamster IgG HM79-12 FITC Ms F
0.5 mg / €410.00
  Acris Antibodies GmbH

CD79b antibody

CD79b Hamster IgG HM79-12 Low Endotoxin Ms C, F, IP, WB
0.5 mg / €440.00
  Acris Antibodies GmbH

CD79b antibody

Immunofluorescent Staining: BALB/c splenocytes were incubated with either Hamster IgG (as an Isotype Control) or purified Hamster anti-Mouse CD79, and then stained with Mouse anti-Hamster IgG (H+L)-FITC. Small lymphocytes were gated and analyzed on a FACScan(TM) flow cytometer (BDIS, San Jose, CA). Amount Used: 1 µg/10e6 cells. Hamster IgG HM79-12 Purified Ms C, F, IP, WB
0.5 mg / €350.00
  Acris Antibodies GmbH

CD79b antibody

CD79b Hamster IgG HM79-12 PE Ms F
0.1 mg / €280.00
  Acris Antibodies GmbH

CD79b antibody

CD79b Mouse IgG1 CB3-1 APC Hu F
100 Tests / €360.00
  Acris Antibodies GmbH

CD79b antibody

CD79b Mouse IgG1 CB3-1 Biotin Hu F, IP
100 Tests / €270.00
  Acris Antibodies GmbH

CD79b antibody

CD79b Mouse IgG1 CB3-1 FITC Hu F
100 Tests / €270.00
  Acris Antibodies GmbH

CD79b antibody

CD79b Mouse IgG1 CB3-1 Purified Hu C, F, IP
0.1 mg / €200.00
  Acris Antibodies GmbH

CD79b antibody

CD79b Mouse IgG1 CB3-1 PE Hu F
100 Tests / €280.00
  Acris Antibodies GmbH

CD79b antibody

Staining of Mouse spleen cells with Hamster Anti Mouse CD79b-FITC (SM1576F/FT). Hamster IgG HM79-11 FITC Ms F
0.1 mg / €280.00
  Acris Antibodies GmbH

CD79b antibody

Staining of Mouse spleen cells with Hamster Anti Mouse CD79b-FITC (SM1576F/FT). Hamster IgG HM79-11 FITC Ms F
25 µg / €190.00
  Acris Antibodies GmbH

CD79b antibody

Staining of Mouse spleen cells with Hamster Anti Mouse CD79b-FITC (SM1576FX). Hamster IgG HM79-11 FITC Ms F
0.5 mg / €560.00
  Acris Antibodies GmbH

CD79b antibody

CD79b Hamster IgG HM79-11 Purified Ms C, F, IP, WB
0.25 mg / €400.00
  Acris Antibodies GmbH

CD79b antibody

CD79b Hamster IgG HM79-11 Purified Ms C, F, IP, WB
0.1 mg / €240.00
  Acris Antibodies GmbH

CD79b antibody

CD79b Hamster IgG HM79-11 Purified Ms C, F, IP, WB
25 µg / €170.00
  Acris Antibodies GmbH

CD79b antibody

Staining of mouse splenocytes with Hamster Anti Mouse CD79b-RPE (SM1576R/RT). Hamster IgG HM79-11 PE Ms F
100 Tests / €300.00
  Acris Antibodies GmbH

CD79b antibody

Staining of mouse splenocytes with Hamster Anti Mouse CD79b-RPE (SM1576R/RT). Hamster IgG HM79-11 PE Ms F
25 Tests / €200.00
  Acris Antibodies GmbH

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