CD93 / C1QR1 antibody

Principal name

CD93 / C1QR1 antibody

Alternative names for CD93 / C1QR1 antibody

MXRA4, CDw93, C1q receptor, MBL receptor, SPA receptor, Complement component C1q receptor, Complement component 1 q subcomponent receptor 1, C1q/MBL/SPA receptor, Matrix-remodeling-associated protein 4

SwissProt ID

O89103 (Mouse), Q9ET61 (Rat), Q9NPY3 (Human)

Gene ID

22918 (CD93), 17064 (Cd93), 84398

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

Frozen Sections (C), Flow Cytometry (F), Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Immunoprecipitation (IP), Paraffin Sections (P)

Background of CD93 / C1QR1 antibody

The monoclol antibody R139 recognizes human CD93, also known as C1qRp. The glycoprotein CD93 binds to C1q, the subunit of the complement protein, mannose binding lectin and pulmory surfactant protein A. CD93 is predicted to play a role in the clearance of apoptotic cells. Expression of CD93 is confined to myeloid cells with higher expression on monocytes than neutrophils, eosinophils, platelets and endothelial cells. Expression on DC?? is downregulated upon maturation. Additiolly, CD93 has been shown to define an early bone marrow stem cell population of hematopoietic and hepatic precursors. The monoclol antibody R139 blocks C1q-mediated enhancement of phagocytosis. CD93 can be shed from the cell surface. This phenomenon can be measured using R3 antibody as detection with R139 as capture to detect soluble CD93 by ELISA. The epitope for R139 resides in the EGF domains.

General readings

SHAW,S. et al. Leucocyte Typing V: White Cell Differentiation Antigens, Oxford University Press (1994) Ed. Schlossmann, S. et al. Abstracts M016, M017, M020, M023, M031, M034, M037, M049, M060, M061, M062, M066, M081, M097, M111, M112, M127, M132, M133, M145, M151. (X-2 Workshop Codes = M48, BP261).

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CD93 / C1QR1 antibody

Immunohistochemicaldetection CD93 on frozen section of vascular endothelial cells in human kidney (1), human colon (2), human testis (3) and human bladder (4) with AM26516AF-N.These frozen sections were kindly provided by Dr. Hiroaki Kataoka, M.D. (Second Department of Pathology, Miyazaki University School of Medicine) and Dr. Nobunao Ikewaki, Ph.D. (Institute of Immunology, Kyushu University of Health and Welfare). Mouse IgG1 mNI-11 Azide Free Hu C, F, IP
0.1 mg / €320.00
  Acris Antibodies GmbH

CD93 / C1QR1 antibody

  Mouse Anti-Human CD93 Purified (25 ug)  
Staining of normal human peripheral blood cells with 0.25 ug of Mouse IgG2b kappa Isotype Control Purified (open histogram) or 0.25 ug of Anti-Human CD93 Purified (filled histogram).  Cells in the monocyte gate were used for analysis. Mouse R139 Purified Hu E, F, IP, WB
25 µg / €120.00
  OriGene Technologies, Inc.

CD93 / C1QR1 antibody

  Anti-CD93 Rabbit Polyclonal Antibody  
Predicted cell location: Cytoplasm . Positive control: Human gastric and ovarian cancer tissue . Recommended dilution: 1/50-200  The image on the left is immunohistochemistry of paraffin-embedded human gastric cancer tissue using CD93 antibody at dilution 1/60, on the right is treated with the synthetic peptide. (Original magnification:x 200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

CD93 / C1QR1 antibody

  Anti-CD93 Rabbit Polyclonal Antibody  
Predicted cell location: Cytoplasm . Positive control: Human cervical and gastric cancer tissue . Recommended dilution: 1/50-200  The image on the left is immunohistochemistry of paraffin-embedded human cervical cancer tissue using CD93 antibody at dilution 1/50, on the right is treated with the synthetic peptide. (Original magnification:x 200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

CD93 / C1QR1 antibody

Flow cytometric analysis of CD93 expression on Jurkatcells (left) and U937 cells (right). Open histograms indicate the reaction of isotypic control to the cells. Shaded histograms indicate the reaction of AM26516RP-N to the cells. Mouse IgG1 mNI-11 PE Hu F
50 Tests / €320.00
  Acris Antibodies GmbH

CD93 / C1QR1 antibody

CD93 / C1QR1 Mouse IgG1 X-2 Purified Hu C, F
0.1 mg / €420.00
  Acris Antibodies GmbH

CD93 / C1QR1 antibody

Human Placenta Frozen Section stained with Biotin conjugated CD93 / C1QR1 Antibody Cat.-No BM4030B. Mouse IgG1 X-2 Biotin Hu C, F
0.1 mg / €460.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

CD93 - human gene knockout kit via CRISPR

CD93 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

CD93 - human gene knockout kit via CRISPR

CD93 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

CD93 - human gene knockout kit via CRISPR

CD93 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

CD93 - human gene knockout kit via CRISPR

CD93 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Cd93 - mouse gene knockout kit via CRISPR

Cd93 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Cd93 - mouse gene knockout kit via CRISPR

Cd93 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Cd93 - mouse gene knockout kit via CRISPR

Cd93 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Cd93 - mouse gene knockout kit via CRISPR

Cd93 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

CD93 / C1QR1

  Recombinant protein of human CD93 molecule (CD93)  
CD93 / C1QR1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

CD93 / C1QR1

  Recombinant protein of human CD93 molecule (CD93)  
CD93 / C1QR1 Human > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
10 µg / €399.00
  OriGene Technologies, Inc.

CD93 / C1QR1 (23-572, His-tag)

CD93 / C1QR1 Mouse Purified > 95 % by SDS - PAGE Insect cells
0.25 mg / €940.00
  Acris Antibodies GmbH

CD93 / C1QR1 (23-572, His-tag)

CD93 / C1QR1 Mouse Purified > 95 % by SDS - PAGE Insect cells
50 µg / €300.00
  Acris Antibodies GmbH

Lysates

Catalog No.    

CD93 overexpression lysate

CD93 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

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