CD97 antibody

Principal name

CD97 antibody

Alternative names for CD97 antibody

Leukocyte antigen CD97

SwissProt ID

P48960 (Human), Q8SQA4 (Bovin), Q9Z0M6 (Mouse)

Gene ID

976 (CD97), 26364 (Cd97)

Available reactivities

Hu (Human), Ms (Mouse), Chimp (Chimpanzee), Mky (Monkey), Rt (Rat)

Available hosts

Mouse, Rabbit, Goat, Rat

Available applications

Immunoprecipitation (IP), Flow Cytometry (F), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Frozen Sections (C), Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Neutralisation (NEUT)

Background of CD97 antibody

This gene is a member of the EGF-TM7 family of class II seven-span transmembrane (7-TM) molecules, likely encoded by a gene cluster on the short arm of chromosome 19. The encoded product is a glycoprotein that is present on the surface of most activated leukocytes and spans the membrane seven times, which is a defining feature of G protein-coupled receptors. The protein has an extended extracellular region with several N-terminal epidermal growth factor (EGF)-like domains, which mediate binding to its cellular ligand, decay accelerating factor (DAF, CD55), a regulatory protein of the complement cascade. The presence of structural features characteristic of extracellular matrix proteins and transmembrane proteins suggests that this protein is a receptor involved in both cell adhesion and signaling processes early after leukocyte activation. Alternative splicing has been observed for this gene and three variants have been found. [provided by RefSeq]. Transcript Variant: This variant (2) lacks an in-frame segment compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

General readings

1. Visser L, de Vos AF, Hamann J, Melief MJ, van Meurs M, van Lier RA, Laman JD, Hintzen RQ. Expression of the EGF-TM7 receptor CD97 and its ligand CD55 (DAF) in multiple sclerosis. J Neuroimmunol. 2002 Nov;132(1-2):156-63.
2. Galle J, Sittig D, Hanisch I, Wobus M, Wandel E, Loeffler M, Aust G: Individual cell-based models of tumor-environment interactions: Multiple effects of CD97 on tumor invasion. Am J Pathol. 2006 Nov;169(5):1802-11.
3. Abbott RJ, Spendlove I, Roversi P, Fitzgibbon H, Knott V, Teriete P, McDonnell JM, Handford PA, Lea SM: Structural and functional characterization of a novel T cell receptor co-regulatory protein complex, CD97-CD55. J Biol Chem. 2007 Jul 27;282(30):22023-32.
4. Wang T, Tian L, Haino M, Gao JL, Lake R, Ward Y, Wang H, Siebenlist U, Murphy PM, Kelly K: Improved antibacterial host defense and altered peripheral granulocyte homeostasis
in mice lacking the adhesion class G protein receptor CD97. Infect Immun. 2007 Mar;75(3):1144-53.
5. Leukocyte Typing VI., Kishimoto T. et al. (Eds.), Garland Publishing Inc. (1997).
Wobus M, Vogel B, Schmücking E, Hamann J, Aust G: N-glycosylation of CD97 within the EGF domains is crucial for epitope accessibility in normal and malignant cells as well as CD55 ligand binding. Int J Cancer. 2004 Dec 10;112(5):815-22.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CD97 (C-term) antibody

Figure 2. Staining of Mouse Colon using AP32070PU-N CD97 antibody at 1 µg/ml (wt, left lane, knock-out right lane) lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by infrared fluorescence (Odyssey). Data obtained from anonymous customer. Goat Aff - Purified Ms E, WB
0.1 mg / €340.00
  Acris Antibodies GmbH

CD97 antibody

Western blot analysis of extracts from Jurkat cells, using CD97a (Cleaved-Leu530) antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CD97 antibody

Western blot analysis of extracts from Jurkat cells, treated with etoposide (25uM, 24hours), using CD97ß (Cleaved-Ser531) antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CD97 (1-512) antibody

WB using anti-CD97 antibody shows detection of bands corresponding to free Fc-CD97- (5EGF) (lower arrowhead) and Fc-CD97- (5EGF) present as a complex (upper arrowhead) in lysates from COS cells. The left lane contains lysate from cells transfected with control DNA. The right lane contains lysate from COS cells expressing Fc-CD97- (5EGF). The formation of the CD97 complex is currently under investigation. A 1:1,000 dilution of the primary antibody was used. Rabbit IgG Purified Ms E, ICC/IF, WB
0.5 mg / €325.00
  OriGene Technologies, Inc.

CD97 antibody

Anti-CD97 antibody IHC of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Purified Hu, Mky
50 µg / €379.00
  OriGene Technologies, Inc.

CD97 (220-270) antibody

Spleen: Formalin-Fixed Paraffin-Embedded (FFPE) Rabbit IgG Aff - Purified Hu, Mky P, WB
50 µg / €470.00
  Acris Antibodies GmbH

CD97 antibody

Peripheral Human Granulocytes stained with Mouse Anti Human CD97-APC (SM1601APC). Mouse IgG1 MEM-180 APC Hu F
100 Tests / €430.00
  Acris Antibodies GmbH

CD97 antibody

CD97 Mouse IgG1 MEM-180 FITC Hu F
0.1 mg / €470.00
  Acris Antibodies GmbH

CD97 antibody

SM1601P staining of peripheral blood leucocytes. Mouse IgG1 MEM-180 Purified Hu C, F
0.2 mg / €590.00
  Acris Antibodies GmbH

CD97 antibody

CD97 Mouse IgG1 MEM-180 Purified Hu F, IP
0.1 mg / €220.00
  Acris Antibodies GmbH

CD97 antibody

CD97 Mouse IgG1 MEM-180 PE Hu F
100 Tests / €480.00
  Acris Antibodies GmbH

CD97 antibody

CD97 Mouse IgG1 MEM-180 PE Hu F
25 Tests / €220.00
  Acris Antibodies GmbH

CD97 (N-term) antibody

Cells expressing vector only - immunostained with target antibody Rabbit Aff - Purified Hu, Mky ICC/IF, P
50 µg / €470.00
  Acris Antibodies GmbH

CD97 (3rd Cytopl. Dom.) antibody

Immunohistochemical staining of Bone Marrow using anti- CD97 antibody SP4365P Rabbit Aff - Purified Bear, Bov, Bt, Can, Elephant, Hst, Hu, Ms, Op, Platypus, Por, Prim, Rt ICC/IF, P
50 µg / €470.00
  Acris Antibodies GmbH

CD97 antibody

CD97 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

CD97 antibody

Western Blot analysis of CD97 expression in transfected 293T cell line (H00000976-T01) by CD97 MaxPab polyclonal antibody.

Lane 1: CD97 transfected lysate(81.62 KDa).
Lane 2: Non-transfected lysate. Mouse Purified Hu E(detection), F, WB
50 µg / €370.00
  Abnova Taiwan Corp.

CD97 antibody

Western Blot analysis of CD97 expression in transfected 293T cell line by CD97 monoclonal antibody (M01), clone 5D5.

Lane 1: CD97 transfected lysate(81.7 KDa).
Lane 2: Non-transfected lysate. Mouse IgG2a 5D5 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

CD97 antibody

CD97 Mouse IgG2b 3B11 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

CD97 antibody

CD97 Mouse IgG1 MEM-180 Hu F, IP
0.1 mg / €390.00
  Abnova Taiwan Corp.

CD97 antibody

CD97 Mouse IgG1 MEM-180 Hu F
100 reaction / €390.00
  Abnova Taiwan Corp.

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