CD98LC / SLCA5 antibody

Principal name

CD98LC / SLCA5 antibody

Alternative names for CD98LC / SLCA5 antibody

LAT1, MPE16, 4F2 light chain, Large neutral amino acids transporter small subunit 1, L-type amino acid transporter 1, Solute carrier family 7 member 5, y+ system cationic amino acid transporter, CD98 light chain, Integral membrane protein E16

SwissProt ID

Q01650 (Human), Q63016 (Rat), Q7YQK4 (Rabit), Q9Z127 (Mouse)

Gene ID

8140 (SLC7A5)

Available reactivities

Hu (Human), Can (Canine), Ms (Mouse), Rt (Rat), Rb (Rabbit), Bov (Bovine), Eq (Equine), Mky (Monkey)

Available hosts

Rabbit, Mouse, Goat

Available applications

Paraffin Sections (P), Frozen Sections (C), Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Flow Cytometry (F), Immunoprecipitation (IP), Immunohistochemistry (IHC)

Background of CD98LC / SLCA5 antibody

Sodium-independent, high-affinity transport of large neutral amino acids such as phenylalanine, tyrosine, leucine, arginine and tryptophan, when associated with SLC3A2/4F2hc. Involved in cellular amino acid uptake. Acts as an amino acid exchanger. Involved in the transport of L-DOPA across the blood-brain barrier, and that of thyroid hormones triiodothyronine (T3) and thyroxine (T4) across the cell membrane in tissues such as placenta. Plays a role in neuronal cell proliferation (neurogenesis) in brain. Involved in the uptake of methylmercury (MeHg) when administered as the L-cysteine or D,L-homocysteine complexes, and hence plays a role in metal ion homeostasis and toxicity. Involved in the cellular activity of small molecular weight nitrosothiols, via the stereoselective transport of L-nitrosocysteine (L-CNSO) across the transmembrane. May play an important role in high-grade gliomas. Mediates blood-to-retina L-leucine transport across the inner blood-retinal barrier which in turn may play a key role in maintaining large neutral amino acids as well as neurotransmitters in the neural retina. Acts as the major transporter of tyrosine in fibroblasts.

General readings

Ohno Y, Suda K, Masuko K, Yagi H, Hashimoto Y, Masuko T.
Production and characterization of highly tumor-specific rat monoclonal antibodies recognizing the extracellular domain of human L-type amino-acid transporter 1. Cancer Sci. 2008 May;99(5):1000-7.

12 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CD98LC / SLCA5 antibody

(0.3ug/ml) staining of Human Spleen lysate (35ug protein in RIPA buffer) with (B) and without (A) blocking with the immunising peptide. Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Can, Hu E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CD98LC / SLCA5 antibody

Gel: 6%SDS-PAGE,Lysate: 40 µg,,Primary antibody: SLC7A5 Antibody at dilution 1/300 dilution,Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution,Exposure time: 10 seconds Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CD98LC / SLCA5 antibody

Anti-SLC7A5 antibody IHC of human placenta, terminal villi. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Purified Hu, Rb
50 µg / €379.00
  OriGene Technologies, Inc.

CD98LC / SLCA5 antibody

Anti-SLC7A5 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Purified Bov, Eq, Hu
50 µg / €379.00
  OriGene Technologies, Inc.

CD98LC / SLCA5 (Internal) antibody

Anti-SLC7A5 antibody IHC of human placenta, terminal villi. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Aff - Purified Hu, Mky, Prim P
50 µg / €379.00
  OriGene Technologies, Inc.

CD98LC / SLCA5 (N-term) antibody

Anti-SLC7A5 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Aff - Purified Bear, Bt, Can, Chk, Elephant, Hst, Hu, Ms, Op, Platypus, Prim, Rb, Rt P
50 µg / €379.00
  OriGene Technologies, Inc.

CD98LC / SLCA5 antibody

CD98LC / SLCA5 Mouse Hu WB
0.5 mg / €1,400.00
  Abnova Taiwan Corp.

CD98LC / SLCA5 antibody

Immunohistochemical analysis of human stomach papillary adenocarcinoma tissue, using SLC7A5 monoclonal antibody, clone 4D9 ( Cat # MAB1711 ) . Mouse IgM 4D9 Hu C
20 µg / €740.00
  Abnova Taiwan Corp.

CD98LC / SLCA5 antibody

CD98LC / SLCA5 Rabbit Hu C
25 µg / €660.00
  Abnova Taiwan Corp.

CD98LC / SLCA5 antibody

CD98LC / SLCA5 Mouse IgM 4D9 Purified Hu P
20 µg / €700.00
  Funakoshi Co., Ltd.

CD98LC / SLCA5 antibody

CD98LC / SLCA5 Rabbit Aff - Purified Hu IHC
25 µg / €630.00
  Funakoshi Co., Ltd.

CD98LC / SLCA5 antibody

CD98LC / SLCA5 Goat Aff - Purified Can, Hu E, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

12 Item(s)

per page
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