CDC45L antibody

Principal name

CDC45L antibody

Alternative names for CDC45L antibody

CDC45-related protein, CDC45L2, PORC-PI-1, PORCPI1

SwissProt ID

O75419 (Human), Q9YHZ6 (Xenla), Q9Z1X9 (Mouse)

Gene ID

8318 (CDC45), 12544 (Cdc45)

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Chk (Chicken), Ms (Mouse), Rt (Rat), African clawed frog, Eq (Equine), GP (Guinea Pig), Rb (Rabbit)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Immunoprecipitation (IP)

Background of CDC45L antibody

CDC45L was identified by its strong similarity with Saccharomyces cerevisiae Cdc45, an essential protein required to the initiation of DNA replication. Cdc45 is a member of the highly conserved multiprotein complex including Cdc6/Cdc18, the minichromosome maintenance proteins (MCMs) and DNA polymerase, which is important for early steps of DNA replication in eukaryotes. This protein has been shown to interact with MCM7 and DNA polymerase alpha. Studies of the similar gene in Xenopus suggested that this protein play a pivotal role in the loading of DNA polymerase alpha onto chromatin. The protein encoded by this gene was identified by its strong similarity with Saccharomyces cerevisiae Cdc45, an essential protein required to the initiation of DNA replication. Cdc45 is a member of the highly conserved multiprotein complex including Cdc6/Cdc18, the minichromosome maintenance proteins (MCMs) and DNA polymerase, which is important for early steps of DNA replication in eukaryotes. This protein has been shown to interact with MCM7 and DNA polymerase alpha. Studies of the similar gene in Xenopus suggested that this protein play a pivotal role in the loading of DNA polymerase alpha onto chromatin. Multiple polyadenlyation sites of this gene are reported. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

General readings

Hoskins,J.M., (2008) Clin. Cancer Res. 14 (6), 1788-1796

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CDC45L antibody

  Rabbit polyclonal antibody to CDC45L (CDC45 cell division cycle 45-like (S. cerevisiae))  
Sample (30 ug of whole cell lysate). A: H1299. 7.5% SDS PAGE. TA308625 diluted at 1:1000 Rabbit IgG Aff - Purified Hu ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CDC45L antibody

  Rabbit Polyclonal Anti-CDC45  
WB Suggested Anti-CDC45 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 12500; Positive Control: Hela cell lysateCDC45 is supported by BioGPS gene expression data to be expressed in HeLa Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

CRISPR

Catalog No. Species Donor Vector  

CDC45 - human gene knockout kit via CRISPR

CDC45 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

CDC45 - human gene knockout kit via CRISPR

CDC45 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

CDC45 - human gene knockout kit via CRISPR

CDC45 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

CDC45 - human gene knockout kit via CRISPR

CDC45 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Cdc45 - mouse gene knockout kit via CRISPR

Cdc45 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Cdc45 - mouse gene knockout kit via CRISPR

Cdc45 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Cdc45 - mouse gene knockout kit via CRISPR

Cdc45 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Cdc45 - mouse gene knockout kit via CRISPR

Cdc45 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

CDC45L

  Recombinant protein of human CDC45 cell division cycle 45-like (S. cerevisiae) (CDC45L)  
CDC45L Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

Lysates

Catalog No.    

CDC45 overexpression lysate

CDC45 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, CDC45 (mGFP-tagged)-Human cell division cycle 45 homolog (S. cerevisiae) (CDC45), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, CDC45 (mGFP-tagged)-Human cell division cycle 45 homolog (S. cerevisiae) (CDC45), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,250.00
  OriGene Technologies, Inc.

Lenti ORF particles, CDC45 (mGFP-tagged) - Human cell division cycle 45 homolog (S. cerevisiae) (CDC45), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, CDC45 (mGFP-tagged) - Human cell division cycle 45 homolog (S. cerevisiae) (CDC45), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, CDC45 (mGFP-tagged)-Human cell division cycle 45 homolog (S. cerevisiae) (CDC45), transcript variant 3, 200 uL, >10^7 TU/mL

Lenti ORF particles, CDC45 (mGFP-tagged)-Human cell division cycle 45 homolog (S. cerevisiae) (CDC45), transcript variant 3, 200 uL, >10^7 TU/mL  
200 µl / €1,140.00
  OriGene Technologies, Inc.

Lenti ORF particles, CDC45 (Myc-DDK-tagged)-Human cell division cycle 45 homolog (S. cerevisiae) (CDC45), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, CDC45 (Myc-DDK-tagged)-Human cell division cycle 45 homolog (S. cerevisiae) (CDC45), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,120.00
  OriGene Technologies, Inc.

Lenti ORF particles, CDC45 (Myc-DDK tagged) - Human cell division cycle 45 homolog (S. cerevisiae) (CDC45), transcript variant 2 , 200 uL, >10^7 TU/mL

Lenti ORF particles, CDC45 (Myc-DDK tagged) - Human cell division cycle 45 homolog (S. cerevisiae) (CDC45), transcript variant 2 , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Lenti ORF particles, CDC45 (Myc-DDK-tagged)-Human cell division cycle 45 homolog (S. cerevisiae) (CDC45), transcript variant 3, 200 uL, >10^7 TU/mL

Lenti ORF particles, CDC45 (Myc-DDK-tagged)-Human cell division cycle 45 homolog (S. cerevisiae) (CDC45), transcript variant 3, 200 uL, >10^7 TU/mL  
200 µl / €1,020.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Cdc45 (GFP-tagged) - Mouse cell division cycle 45 homolog (S. cerevisiae) (Cdc45), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, Cdc45 (GFP-tagged) - Mouse cell division cycle 45 homolog (S. cerevisiae) (Cdc45), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,210.00
  OriGene Technologies, Inc.

Lenti ORF particles, Cdc45 (GFP-tagged) - Mouse cell division cycle 45 homolog (S. cerevisiae) (Cdc45), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, Cdc45 (GFP-tagged) - Mouse cell division cycle 45 homolog (S. cerevisiae) (Cdc45), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €1,150.00
  OriGene Technologies, Inc.

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