CDC6 antibody

Principal name

CDC6 antibody

Alternative names for CDC6 antibody

CDC18L, CDC6-related protein, p62(cdc6), HsCDC6, Cdc18-related protein, HsCdc18, Cell division control protein 6 homolog

SwissProt ID

O89033 (Mouse), P09119 (Yeast), Q99741 (Human)

Gene ID

990 (CDC6), 23834 (Cdc6)

Available reactivities

Hu (Human), Ms (Mouse), Mky (Monkey), Rt (Rat)

Available hosts

Mouse, Rabbit, Goat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection))

Background of CDC6 antibody

In yeasts, Cdc6 (Saccharomyces cerevisiae) and Cdc18 (Schizosaccharomyces pombe) associate with the origin recognition complex (ORC) proteins to render cells competent for DNA replication. Cdc6 is overexpressed in human cancers, where it has a critical regulatory role in addition to DNA replication. Yan et al. (1998) showed that Cdc6 is expressed selectively in proliferating but not quiescent mammalian cells, both in culture and within tissues in intact animals. During the transition from a growth-arrested to a proliferative state, transcription of mammalian Cdc6 is regulated by E2F proteins, as revealed by a functional analysis of the human Cdc6 promoter and by the ability of exogenously expressed E2F proteins to stimulate the endogenous Cdc6 gene. They conclude that expression of human Cdc6 is regulated in response to mitogenic signals though transcriptional control mechanisms involving E2F proteins, and that Cdc6 is required for initiation of DNA replication in mammalian cells.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CDC6 antibody

  CDC6 mouse monoclonal antibody, clone OTI1A4 (formerly 1A4)  
Immunohistochemical staining of paraffin-embedded Carcinoma of Human liver tissue using anti-CDC6 mouse monoclonal antibody.(Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer (pH8.5) at 120°C for 3 min, TA808381)(1:150) Mouse IgG1 OTI1A4 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CDC6 antibody

Staining of nuclear Jurkat lysate using CDC6 ANtibody Cat.-No AP32719PU-N at 0.01 µg/ml (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Hu WB
0.1 mg / €350.00
  Acris Antibodies GmbH

CDC6 antibody

  Anti-CDC6 Rabbit Polyclonal Antibody  
Predicted band size: 63 kDa . Positive control: K562 and 293T cell lysate. Recommended dilution: 1/200-1000. (Gel: 10%SDS-PAGE Lane1: K562 cell lysate Lane2: 293T cell lysate Lysates: 40 ug per lane Primary antibody: 1/400 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 2 minutes) Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CDC6 antibody

  Anti-CDC6 Rabbit Polyclonal Antibody  
Predicted band size: 63 kDa . Positive control: K562 cell lysate. Recommended dilution: 1/200-1000. (Gel: 10%SDS-PAGE Lysate: 40 ug per lane Primary antibody: 1/200 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 2 minutes) Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CDC6 antibody

  CDC6 mouse monoclonal antibody, clone OTI7B12 (formerly 7B12)  
Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-CDC6 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min, TA808380)(1:150) Mouse IgG1 OTI7B12 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CDC6 antibody

  CDC6 mouse monoclonal antibody, clone OTI1B3 (formerly 1B3)  
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CDC6 (RC206814, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CDC6.(1:2000) Mouse IgG1 OTI1B3 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CDC6 antibody

CDC6 Mouse IgG1 IMD-6 Aff - Purified Hu WB
0.1 mg / €340.00
  Acris Antibodies GmbH

CDC6 antibody

Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue using CDC6 antibody (Cat.-No. AP06045PU-N). Rabbit Aff - Purified Hu, Ms P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

CDC6 antibody

Western blot (WB) analyzes of Cdc6 antibody (Cat.-No.: AP06778PU-N) in extracts from K562 cells.. Rabbit Aff - Purified Hu WB
0.1 mg / €350.00
  Acris Antibodies GmbH

CDC6 (400-500) antibody

Testis: Formalin-Fixed Paraffin-Embedded Rabbit IgG Aff - Purified Hu, Ms P, WB
50 µl / €470.00
  Acris Antibodies GmbH

CDC6 pSer54 antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. Rabbit Ig Aff - Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CDC6 (N-term) antibody

Western blot analysis of Cdc6 Antibody (N-term) in Romas cell line lysates (35ug/lane). Cdc6 (arrow) was detected using the purified Pab (1:60 dilution). Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CDC6 pSer54 antibody

Immunohistochemistry analysis of paraffin-embedded human lung carcinoma, using CDC6 (Phospho-Ser54) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, P, WB
50 µg / €230.00
  Assay Biotech

CDC6 pSer54 antibody

Immunohistochemistry analysis of paraffin-embedded human lung carcinoma, using CDC6 (Phospho-Ser54) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, P, WB
0.1 mg / €330.00
  Assay Biotech

CDC6 antibody

Immunohistochemistry analysis of paraffin-embedded human brain tissue, using CDC6 (Ab-54) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, P, WB
50 µg / €230.00
  Assay Biotech

CDC6 antibody

Immunohistochemistry analysis of paraffin-embedded human brain tissue, using CDC6 (Ab-54) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, P, WB
0.1 mg / €330.00
  Assay Biotech

CDC6 antibody

Western blot analysis of extracts from K562 cells, using CDC6 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, WB
50 µg / €230.00
  Assay Biotech

CDC6 antibody

Western blot analysis of extracts from K562 cells, using CDC6 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, WB
0.1 mg / €330.00
  Assay Biotech

CRISPR

Catalog No. Species Donor Vector  

CDC6 - human gene knockout kit via CRISPR

CDC6 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

CDC6 - human gene knockout kit via CRISPR

CDC6 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

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