CDK1 antibody

Principal name

CDK1 antibody

Alternative names for CDK1 antibody

CDK1, CDC2, CDC28A, CDKN1, P34CDC2, p34 protein kinase, Cyclin-dependent kinase 1, Cell division control protein 2 homolog, Cell division protein kinase 1

SwissProt ID

P00546, P04551, P06493 (Human), P11440 (Mouse), P13863 (Chick), P23572, P24033, P34112 (Dicdi), P34556 (Caeel), P35567 (Xenla), P39951, P48734

Gene ID

983 (CDK1), 380246 (cdk1-a), 54237 (Cdk1), 379785 (cdk1-b), 396252, 12534

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Xen (Xenopus), Mink, Mky (Monkey), Chk (Chicken), Ze (Zebrafish), Frog, Arabidopsis, Dros (Drosophila), Can (Canine), Por (Porcine), Rb (Rabbit), GP (Guinea Pig), Amph (Amphibian)

Available hosts

Rabbit, Mouse

Available applications

Frozen Sections (C), Immunoprecipitation (IP), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Enzyme Immunoassay (E), Functional assay (FN), Dot blot (Dot), ELISA (detection) (E(detection)), Flow Cytometry (F)

Background of CDK1 antibody

The protein encoded by CDC2 is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control. The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control.

General readings

Draetta, G.; Piwnica-Worms, H.; Morrison, D.; Druker, B.; Roberts, T.; Beach, D. : Human CDC2 protein kinase is a major cell-cycle regulated tyrosine kinase substrate. Nature 336: 738-744, 1988.
2. Spurr, N. K.; Goodfellow, P. N.; Nurse, P.; Lee, M. : Assignment of the human homologue of the yeast cell cycle control gene CDC2 to chromosome 10. (Abstract) Cytogenet. Cell Genet. 46: 698, 1987.
3. Nazarenko, S. A.; Ostroverhova, N. V.; Spurr, N. K. : Regional assignment of the human cell cycle control gene CDC2 to chromosome 10q21 by in situ hybridization. Hum. Genet. 87: 621-622, 1991.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CDC2 antibody

Western blot analysis of CDC2 expression in HepG2 (A); MCF7 (B); NIH3T3 (C) whole cell lysates. Rabbit Aff - Purified Bov, Chk, Hu, Mky, Ms, Rt, Ze WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

CDC2 antibody

Western blot analysis of CDC2 expression in HepG2 (A); MCF7 (B); NIH3T3 (C) whole cell lysates. Rabbit Aff - Purified Bov, Chk, Hu, Mky, Ms, Rt, Ze WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

CDC2 antibody

Western blot analysis of CDC2 expression in HepG2 (A); MCF7 (B); NIH3T3 (C) whole cell lysates. Rabbit Aff - Purified Bov, Chk, Hu, Mky, Ms, Rt, Ze WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

CDK1 antibody

Immunohistochemistry staining of Human thymus (paraffin sections) using anti-Cdk1 (clone POH-1). Mouse IgG2a POH-1 Purified Bov, Hu ICC/IF, IP, P, WB
0.1 mg / €230.00
  Acris Antibodies GmbH

CDK1 antibody

Immunohistochemical analysis of paraffin-embedded ovarian cancer tissues (left) and lung cancer tissues (right) using CDK1 antibody Cat.-No AM06594SU-N with DAB staining. Mouse IgG1 2G9 Ascites Hu, Mky, Ms, Rt E, ICC/IF, P, WB
0.1 ml / €430.00
  Acris Antibodies GmbH

CDK1 antibody

Immunoperoxidase of monoclonal antibody to CDC2 on formalin-fixed paraffin-embedded human small Intestine. [antibody concentration 0.3 ug/ml] Mouse IgG1 1A4-1A9 Purified Hu E, ICC/IF, P, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

CDK1 antibody

CDC2 monoclonal antibody (M03), clone 1G10. Western Blot analysis of CDC2 expression in NIH/3T3(Cat # L018V1 ). Mouse IgG 1G10 Purified Hu, Ms, Rt E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

CDK1 antibody

Immunoperoxidase of monoclonal antibody to CDC2 on formalin-fixed paraffin-embedded human tonsil. [antibody concentration 1.5 ug/ml] Mouse IgG2a 8F1 Purified Hu, Ms, Rt E, P, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

CDK1 pSer39 antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with CDC2 (phospho S39) polyclonal antibody ( Cat # PAB0436 ) which was peroxidase-conjugated to the secondary antibody followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. HC = hepatocarcinoma. Rabbit Hu Dot, P, WB
0.4 ml / €400.00
  Abnova Taiwan Corp.

CDK1 antibody

AP15458PU Cdc2 p34 antibody staining of Human Tonsil. Rabbit Purified Hu, Ms, Rt P, WB
0.5 ml / €360.00
  Acris Antibodies GmbH

CDK1 antibody

AP15458PU Cdc2 p34 antibody staining of Human Tonsil. Rabbit Purified Hu, Ms, Rt P, WB
1 ml / €440.00
  Acris Antibodies GmbH

CDK1 antibody

AP15458PU Cdc2 p34 antibody staining of Human Tonsil. Rabbit Purified Hu, Ms, Rt P, WB
0.1 ml / €180.00
  Acris Antibodies GmbH

CDK1 antibody

Western blot analysis of CDK1(arrow) using rabbit polyclonal CDK1 Antibody (T14) (Cat.#TA302013). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the CDK1 gene (Lane 2) (Origene Technologies). Rabbit Ig Aff - Purified Hu P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CDK1 (C-term) antibody

Western blot analysis of CDC2 (arrow) using rabbit polyclonal CDC2 Antibody (C-term) (Cat.#TA302014).293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the CDC2 gene (Lane 2) (Origene Technologies). Rabbit Ig Aff - Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CDK1 (N-term) antibody

Western blot analysis of CDC2 Antibody (N-term) in 293 cell line lysates (35ug/lane). CDC2 (arrow) was detected using the purified Pab. Rabbit Ig Aff - Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CDK1 antibody

Anti-Cdc2 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200. Mouse IgG2a 26E11 Purified Hu, Ms, Rt E, IP
50 µl / €345.00
  OriGene Technologies, Inc.

CDK1 antibody

Western blot analysis of Jurkat, Hela and HT-29 cell using TA321398(CDK1 Antibody) at dilution 1/300 Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CDK1 antibody

Western blot analysis of CDC2 expression in HepG2 whole cell lysates,The lane on the left is treated with the antigen-specific peptide. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CDK1 antibody

Western blot analysis of extracts from HepG2 cells, using CDC2 (Ab-161) Antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CDK1 antibody

Western blot analysis of extracts from Jurkat cells, COLO205 cells and HUVEC, using CDC2 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

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