CDK1 antibody

Principal name

CDK1 antibody

Alternative names for CDK1 antibody

CDK1, CDC2, CDC28A, CDKN1, P34CDC2, p34 protein kinase, Cyclin-dependent kinase 1, Cell division control protein 2 homolog, Cell division protein kinase 1

SwissProt ID

P00546, P04551, P06493 (Human), P11440 (Mouse), P13863 (Chick), P23572, P24033, P34112 (Dicdi), P34556 (Caeel), P35567 (Xenla), P39951, P48734

Gene ID

983 (CDK1), 380246 (cdk1-a), 54237 (Cdk1), 12534

Available reactivities

Bov (Bovine), Hu (Human), Ms (Mouse), Rt (Rat), Xen (Xenopus), Ze (Zebrafish), Frog, Chk (Chicken), Arabidopsis, Dros (Drosophila), Can (Canine), Por (Porcine), Rb (Rabbit), Mky (Monkey)

Available hosts

Mouse, Rabbit

Available applications

Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Western blot / Immunoblot (WB), Paraffin Sections (P), Frozen Sections (C), Enzyme Immunoassay (E), Dot blot (Dot), ELISA (detection) (E(detection)), Flow Cytometry (F)

Background of CDK1 antibody

The protein encoded by CDC2 is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control. The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control.

General readings

Draetta, G.; Piwnica-Worms, H.; Morrison, D.; Druker, B.; Roberts, T.; Beach, D. : Human CDC2 protein kinase is a major cell-cycle regulated tyrosine kinase substrate. Nature 336: 738-744, 1988.
2. Spurr, N. K.; Goodfellow, P. N.; Nurse, P.; Lee, M. : Assignment of the human homologue of the yeast cell cycle control gene CDC2 to chromosome 10. (Abstract) Cytogenet. Cell Genet. 46: 698, 1987.
3. Nazarenko, S. A.; Ostroverhova, N. V.; Spurr, N. K. : Regional assignment of the human cell cycle control gene CDC2 to chromosome 10q21 by in situ hybridization. Hum. Genet. 87: 621-622, 1991.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CDK1 antibody

Immunohistochemistry staining of Human thymus (paraffin sections) using anti-Cdk1 (clone POH-1). Mouse IgG2a POH-1 Purified Bov, Hu ICC/IF, IP, P, WB
0.1 mg / €230.00
  Acris Antibodies GmbH

CDK1 antibody

Immunohistochemical analysis of paraffin-embedded ovarian cancer tissues (left) and lung cancer tissues (right) using CDK1 antibody Cat.-No AM06594SU-N with DAB staining. Mouse IgG1 2G9 Ascites Hu, Mky, Ms, Rt E, ICC/IF, P, WB
0.1 ml / €430.00
  Acris Antibodies GmbH

CDK1 antibody

  Rabbit Polyclonal Antibody against CDC2 (T14)  
Western blot analysis of CDK1(arrow) using rabbit polyclonal CDK1 Antibody (T14) (Cat.#TA302013). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the CDK1 gene (Lane 2) (Origene Technologies). Rabbit Ig Aff - Purified Hu P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CDK1 (C-term) antibody

  Rabbit Polyclonal Antibody against CDC2 (C-term)  
Western blot analysis of CDC2 (arrow) using rabbit polyclonal CDC2 Antibody (C-term) (Cat.#TA302014).293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the CDC2 gene (Lane 2) (Origene Technologies). Rabbit Ig Aff - Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CDK1 (N-term) antibody

  Rabbit Polyclonal Antibody against CDC2 (N-term)  
Western blot analysis of CDC2 Antibody (N-term) in 293 cell line lysates (35ug/lane). CDC2 (arrow) was detected using the purified Pab. Rabbit Ig Aff - Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CDK1 antibody

  CDK1 / CDC2 Mouse Monoclonal (26E11) Antibody  
Anti-Cdc2 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200. Mouse IgG2a 26E11 Purified Hu, Ms, Rt E, IP
50 µl / €400.00
  OriGene Technologies, Inc.

CDK1 antibody

  Anti-CDK1 Rabbit Polyclonal Antibody  
Western blot analysis of Jurkat, Hela and HT-29 cell using TA321398(CDK1 Antibody) at dilution 1/300 Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CDK1 antibody

  Rabbit Polyclonal CDC2 Antibody  
Western blot analysis of CDC2 expression in HepG2 whole cell lysates,The lane on the left is treated with the antigen-specific peptide. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CDK1 antibody

  Rabbit Polyclonal CDC2 (Tyr15) Antibody (Phospho-specific)  
Western blot analysis of CDC2 phosphorylation expression in HepG2 whole cell lysates,The lane on the left is treated with the antigen-specific peptide. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CDK1 antibody

  Rabbit polyclonal CDC2 (Ab-161) antibody  
Western blot analysis of extracts from HepG2 cells, using CDC2 (Ab-161) Antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CDK1 antibody

  Rabbit polyclonal CDC2 antibody  
Western blot analysis of extracts from Jurkat cells, COLO205 cells and HUVEC, using CDC2 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CDK1 antibody

  Rabbit anti-CDK1 Polyclonal Antibody  
Western blot analysis of extracts of various cell lines, using CDK1 antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

CDK1 antibody

  Rabbit Polyclonal Anti-CDK1 Antibody  
WB Suggested Anti-CDC2 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:312500; Positive Control: SH-SYSY cell lysateCDK1 is strongly supported by BioGPS gene expression data to be expressed in Human SHSY5Y cells Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

CDK1 antibody

  Rabbit Polyclonal Anti-CDK1 Antibody  
WB Suggested Anti-CDC2 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:12500; Positive Control: Human Muscle Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

CDK1 antibody

  Rabbit Polyclonal Anti-CDK1 Antibody  
WB Suggested Anti-CDC2 Antibody Titration: 0.1ug/ml; Positive Control: Jurkat cell lysateCDK1 is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells Rabbit IgG Purified Hu P, WB
50 µg / €325.00
  OriGene Technologies, Inc.

CDK1 antibody

  Phospho-CDK1-T161 Rabbit Polyclonal Antibody  
Western blot analysis of extracts from Hela cells using Phospho-CDK1-T161 antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

CDK1 antibody

  Rabbit Polyclonal Anti-CDC2 Antibody - middle region  
WB Suggested Anti-CDC2 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:312500; Positive Control: 293T cell lysateCDK1 is strongly supported by BioGPS gene expression data to be expressed in Human HEK293T cells Rabbit IgG Purified WB
50 µg / €325.00
  OriGene Technologies, Inc.

CDK1 antibody

  Rabbit Polyclonal Anti-CDC2 Antibody - middle region  
WB Suggested Anti-CDC2 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:312500; Positive Control: Human Spleen Rabbit IgG Purified WB
50 µg / €325.00
  OriGene Technologies, Inc.

CDK1 antibody

  Mouse Monoclonal CDC2/CDK1 Antibody  
Western blot detection of CDC2/CDK1 in K562,A549,Jurkat and Hela cell lysates using CDC2/CDK1 mouse mAb (1:100 diluted).Predicted band size: 34KDa.Observed band size: 34KDa. Mouse IgG2b 3B9-F8-B12 Purified ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CDK1 antibody

  Rabbit Polyclonal Anti-CDC2 Antibody  
Western blot analysis on A2780 cell lysate using CDC2 Antibody Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

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