CDK18 / PCTK3 antibody

Principal name

CDK18 / PCTK3 antibody

Alternative names for CDK18 / PCTK3 antibody

PCTAIRE-3, PCTAIRE 3, PCTAIRE3, PCTAIRE-motif protein kinase 3, Cyclin-dependent kinase 18, Cell division protein kinase 18, Serine/threonine-protein kinase PCTAIRE-3

SwissProt ID

O35832 (Rat), Q04899 (Mouse), Q07002 (Human)

Gene ID

5129 (CDK18)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Chk (Chicken)

Available hosts

Rabbit, Mouse

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection))

Background of CDK18 / PCTK3 antibody

Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The STE group (homologs of yeast Sterile 7, 11, 20 kinases) consists of 50 kinases related to the mitogen-activated protein kinase (MAPK) cascade families (Ste7/MAP2K, Ste11/MAP3K, and Ste20/MAP4K). MAP kinase cascades, consisting of a MAPK and one or more upstream regulatory kinases (MAPKKs) have been best characterized in the yeast pheromone response pathway. Pheromones bind to Ste cell surface receptors and activate yeast MAPK pathway.The CMGC group consists of 60 kinases including the cyclin-dependent kinase (CDK) and close relatives family, the MAP kinase (ERK) family, the glycogen synthase kinase 3 (GSK3) family, and the Cdc2-like kinase (CLK) family.

General readings

Malumbres, M., et al. Nat. Cell Biol. 11(11):1275-1276(2009)
Wissing, J., et al. Mol. Cell Proteomics 6(3):537-547(2007)
Herskovits, A.Z., et al. Neurobiol. Dis. 23(2):398-408(2006)
Palmer, K.J., et al. J. Cell. Sci. 118 (PT 17), 3839-3847 (2005)
Herskovits, A.Z., et al. Gene 328, 59-67 (2004)

13 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CDK18 / PCTK3 antibody

WB Suggested Anti-PCTK3 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:12500; Positive Control: HepG2 cell lysate Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

CDK18 / PCTK3 (N-term) antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. Rabbit Ig Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CDK18 / PCTK3 (C-term) antibody

Western blot analysis of CDK18 / PCTK3 Antibody (C-term) Cat.-No AP53224PU-N in mouse liver tissue lysates (35ug/lane). This demonstrates the PCTK3 antibody detected the PCTK3 protein (arrow). Rabbit Ig Aff - Purified Hu, Ms WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CDK18 / PCTK3 antibody

Western Blot analysis of PCTK3 expression in transfected 293T cell line (H00005129-T02) by PCTK3 MaxPab polyclonal antibody.

Lane 1: PCTK3 transfected lysate(52.14 KDa).
Lane 2: Non-transfected lysate. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

CDK18 / PCTK3 antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with PCTK3 polyclonal antibody ( Cat # PAB2948 ) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma. Rabbit Hu E, P, WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

CDK18 / PCTK3 antibody

Human HepG2; WB Suggested Anti-PCTK3 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:12500. Positive Control: HepG2 cell lysate; PCTK3 antibody - N-terminal region (AVARP03011_P050) in Human HepG2 cells using Western Blot Rabbit Aff - Purified Bov, Chk, Hu, Ms, Rt P, WB
50 µg / €350.00
  AVIVA Systems Biology

CDK18 / PCTK3 antibody

Western  Blot:  PCTAIRE3 Antibody [NBP1-33487] – Western blot analysis of PCTAIRE3 on Hep G2 lysates using NBP1-33487 at a dilution of 1:1000. 30ug whole cell lysate loaded on 7.5% SDS PAGE gel. Rabbit IgG Hu WB
0.1 ml / €420.00
  Novus Biologicals Inc.

CDK18 / PCTK3 antibody

Immunohistochemistry-Paraffin: PCTAIRE3 Antibody [NBP1-92249] - Immunohistochemical staining of human vulva/anal skin shows strong cytoplasmic positivity in basal layer of epidermal cells and endothelial cells. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

CDK18 / PCTK3 (full length, N-term HIS tag, transcript variant 2)

CDK18 / PCTK3 Human > 80 %
Preparation: .
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
E. coli
50 µg / €199.00
  OriGene Technologies, Inc.

CDK18 / PCTK3

CDK18 / PCTK3 Human
2 µg / €300.00
  Abnova Taiwan Corp.

CDK18 / PCTK3

CDK18 / PCTK3 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

CDK18 / PCTK3

CDK18 / PCTK3 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

PCTK3 293T Cell Transient Overexpression Lysate(Denatured)

PCTK3 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

13 Item(s)

per page
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