CDK18 / PCTK3 antibody

Principal name

CDK18 / PCTK3 antibody

Alternative names for CDK18 / PCTK3 antibody

PCTAIRE-3, PCTAIRE 3, PCTAIRE3, PCTAIRE-motif protein kinase 3, Cyclin-dependent kinase 18, Cell division protein kinase 18, Serine/threonine-protein kinase PCTAIRE-3

SwissProt ID

O35832 (Rat), Q04899 (Mouse), Q07002 (Human)

Gene ID

5129 (CDK18), 18557 (Cdk18), 289019

Available reactivities

Hu (Human), Bov (Bovine), Chk (Chicken), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit, Mouse

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection))

Background of CDK18 / PCTK3 antibody

Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The STE group (homologs of yeast Sterile 7, 11, 20 kinases) consists of 50 kinases related to the mitogen-activated protein kinase (MAPK) cascade families (Ste7/MAP2K, Ste11/MAP3K, and Ste20/MAP4K). MAP kinase cascades, consisting of a MAPK and one or more upstream regulatory kinases (MAPKKs) have been best characterized in the yeast pheromone response pathway. Pheromones bind to Ste cell surface receptors and activate yeast MAPK pathway.The CMGC group consists of 60 kinases including the cyclin-dependent kinase (CDK) and close relatives family, the MAP kinase (ERK) family, the glycogen synthase kinase 3 (GSK3) family, and the Cdc2-like kinase (CLK) family.

General readings

Malumbres, M., et al. Nat. Cell Biol. 11(11):1275-1276(2009)
Wissing, J., et al. Mol. Cell Proteomics 6(3):537-547(2007)
Herskovits, A.Z., et al. Neurobiol. Dis. 23(2):398-408(2006)
Palmer, K.J., et al. J. Cell. Sci. 118 (PT 17), 3839-3847 (2005)
Herskovits, A.Z., et al. Gene 328, 59-67 (2004)

16 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CDK18 / PCTK3 antibody

  Rabbit Polyclonal Anti-CDK18 Antibody  
WB Suggested Anti-PCTK3 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:12500; Positive Control: HepG2 cell lysate Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

CDK18 / PCTK3 (N-term) antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. Rabbit Ig Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CDK18 / PCTK3 (C-term) antibody

Western blot analysis of CDK18 / PCTK3 Antibody (C-term) Cat.-No AP53224PU-N in mouse liver tissue lysates (35ug/lane). This demonstrates the PCTK3 antibody detected the PCTK3 protein (arrow). Rabbit Ig Aff - Purified Hu, Ms WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

CDK18 - human gene knockout kit via CRISPR

CDK18 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

CDK18 - human gene knockout kit via CRISPR

CDK18 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

CDK18 - human gene knockout kit via CRISPR

CDK18 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

CDK18 - human gene knockout kit via CRISPR

CDK18 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Cdk18 - mouse gene knockout kit via CRISPR

Cdk18 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Cdk18 - mouse gene knockout kit via CRISPR

Cdk18 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

CDK18 / PCTK3 (full length, N-term HIS tag, transcript variant 2)

  Recombinant protein of human cyclin-dependent kinase 18 (CDK18), transcript variant 2, full length, with N-terminal HIS tag, expressed in E.Coli, 50ug  
CDK18 / PCTK3 Human > 80 %
Preparation: .
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
E. coli
50 µg / €199.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, CDK18 (mGFP-tagged)-Human cyclin-dependent kinase 18 (CDK18), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, CDK18 (mGFP-tagged)-Human cyclin-dependent kinase 18 (CDK18), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,130.00
  OriGene Technologies, Inc.

Lenti ORF particles, CDK18 (Myc-DDK-tagged)-Human cyclin-dependent kinase 18 (CDK18), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, CDK18 (Myc-DDK-tagged)-Human cyclin-dependent kinase 18 (CDK18), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,010.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Cdk18 (GFP-tagged) - Mouse cyclin-dependent kinase 18 (Cdk18), 200 uL, >10^7 TU/mL

Lenti ORF particles, Cdk18 (GFP-tagged) - Mouse cyclin-dependent kinase 18 (Cdk18), 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, Cdk18 (Myc-DDK-tagged) - Mouse cyclin-dependent kinase 18 (Cdk18), 200 uL, >10^7 TU/mL

Lenti ORF particles, Cdk18 (Myc-DDK-tagged) - Mouse cyclin-dependent kinase 18 (Cdk18), 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Cdk18 (GFP-tagged ORF) - Rat PCTAIRE protein kinase 3 (Pctk3), 200 uL, >10^7 TU/mL

Lenti ORF particles, Cdk18 (GFP-tagged ORF) - Rat PCTAIRE protein kinase 3 (Pctk3), 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, Cdk18 (Myc-DDK-tagged ORF) - Rat PCTAIRE protein kinase 3 (Pctk3), 200 uL, >10^7 TU/mL

Lenti ORF particles, Cdk18 (Myc-DDK-tagged ORF) - Rat PCTAIRE protein kinase 3 (Pctk3), 200 uL, >10^7 TU/mL  
200 µl / €942.00
  OriGene Technologies, Inc.

16 Item(s)

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