CDKN2B / p15INK4b antibody

Principal name

CDKN2B / p15INK4b antibody

Alternative names for CDKN2B / p15INK4b antibody

p14INK4b, MTS2, p14-INK4b, p15-INK4b, Cyclin-dependent kinase 4 inhibitor B, Multiple tumor suppressor 2

SwissProt ID

P42772 (Human), P55271 (Mouse), P55272 (Rat), Q2KJD8 (Bovin)

Gene ID

1030 (CDKN2B)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Mky (Monkey), Por (Porcine)

Available hosts

Mouse, Rabbit, Goat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Frozen Sections (C), Paraffin Sections (P), ELISA (detection) (E(detection)), Flow Cytometry (F)

Background of CDKN2B / p15INK4b antibody

The normal progression of cells through the cell cycle is under the control of the cyclin dependent protein kinases Cdk4 and Cdk6 which are subject to inhibition by the mitotic inhibitory protein, p16. An isolated member of the p16 family has been designated p15. p15 expression is upregulated approximately 30-fold in TGFbeta-treated human keratinocytes, suggesting that p15 may act as an effector of TGFbeta-mediated cell cycle arrest. The gene encoding p15 has been mapped to chromosome 9p21 at a position adjacent to the p16 gene at a site of frequent chromosomal abnormality in human tumors. It has been suggested that p15 may function as an effector of TGFbeta-mediated cell cycle arrest through inhibition of Cdk4 and Cdk6 kinases.

General readings

1. Serra RW  et al. A KRAS-directed transcriptional silencing pathway that mediates the CpG island methylator phenotype. Elife 3:e02313 (2014). WB ; Human .
2. Motterle A  et al. Functional analyses of coronary artery disease associated variation on chromosome 9p21 in vascular smooth muscle cells. Hum Mol Genet 21:4021-9 (2012). Human .
3. Toledano Y  et al. Estradiol partially recapitulates murine pituitary cell cycle response to pregnancy. Endocrinology 153:5011-22 (2012).

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CDKN2B / p15INK4b antibody

Western blot analysis of extracts from HeLa cells, using p15 INK antibody (#TA312926).The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CDKN2B / p15INK4b antibody

Immunohistochemical staining of paraffin-embedded Carcinoma of Human pancreas tissue using anti-CDKN2B mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA505201) Mouse IgG1 OTI2D11 Purified Hu F, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CDKN2B / p15INK4b antibody

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-CDKN2B mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA505206) Mouse IgG1 OTI3B6 Purified Hu F, P, WB
0.1 ml / €379.00
  OriGene Technologies, Inc.

TrueMAB

CDKN2B / p15INK4b antibody

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-CDKN2B mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA505208) Mouse IgG1 OTI8H4 Purified Hu ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CDKN2B / p15INK4b (Isoform 2) (C-term) antibody

AP32957PU-N (1 µg/ml) staining of Human Gastrointestinal cancer lysate (35µg protein in RIPA buffer) with (B) and without (A) blocking with the immunizing peptide. Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Hu E, WB
0.1 mg / €340.00
  Acris Antibodies GmbH

CDKN2B / p15INK4b antibody

WB Suggested Anti-CDKN2B Antibody Titration: 0.2-1 ug/ml; Positive Control: Jurkat cell lysate Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

CDKN2B / p15INK4b antibody

Western blot analysis on HeLa cell lysate using p15 INK Antibody Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CDKN2B / p15INK4b antibody

Western blot analysis of p15 INK expression in HeLa cell extract Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CDKN2B / p15INK4b antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CDKN2B (RC204895, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CDKN2B. Mouse IgG1 OTI3E4 Purified Hu F, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CDKN2B / p15INK4b antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CDKN2B (RC204895, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CDKN2B. Mouse IgG2b OTI7C4 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CDKN2B / p15INK4b antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CDKN2B (RC204895, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CDKN2B. Mouse IgG1 OTI1H5 Purified Hu F, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CDKN2B / p15INK4b antibody

CDKN2B / p15INK4b Mouse IgG1 DCS-114.1 Purified Hu C, IP, WB
0.1 mg / €360.00
  Acris Antibodies GmbH

CDKN2B / p15INK4b antibody

Immunoflourescence detection of p15INK4b transfected 293T cells with AM26641AF-N. Mouse IgG1 1F6 Azide Free Hu ICC/IF, IP, WB
0.1 mg / €320.00
  Acris Antibodies GmbH

CDKN2B / p15INK4b antibody

Immunohistochemistry (IHC) analyzes of p15 INK antibody (Cat.-No.: AP06261PU-N)  in paraffin-embedded human lung carcinoma tissue. Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

CDKN2B / p15INK4b antibody

CDKN2B / p15INK4b Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

CDKN2B / p15INK4b antibody

Western Blot analysis of CDKN2B expression in transfected 293T cell line (H00001030-T01) by CDKN2B MaxPab polyclonal antibody.

Lane 1: CDKN2B transfected lysate(15.29 KDa).
Lane 2: Non-transfected lysate. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

CDKN2B / p15INK4b antibody

Western Blot analysis of CDKN2B expression in transfected 293T cell line by CDKN2B monoclonal antibody (M07), clone 8C4.

Lane 1: CDKN2B transfected lysate(14.7 KDa).
Lane 2: Non-transfected lysate. Mouse IgG2a 8C4 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

CDKN2B / p15INK4b antibody

CDKN2B / p15INK4b Hu
0.1 mg / €400.00
  Abnova Taiwan Corp.

CDKN2B / p15INK4b antibody

Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using p15 INK Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, P, WB
50 µg / €205.00
  Assay Biotech

CDKN2B / p15INK4b antibody

Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using p15 INK Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, P, WB
0.1 mg / €310.00
  Assay Biotech

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