CDNF antibody

Principal name

CDNF antibody

Alternative names for CDNF antibody

ARMET-like protein 1, ARMETL1, Cerebral dopamine neurotrophic factor, Conserved dopamine neurotrophic factor

SwissProt ID

P0C5I0 (Rat), Q49AH0 (Human), Q8CC36 (Mouse)

Gene ID

441549 (CDNF)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit), Ze (Zebrafish)

Available hosts

Rabbit, Mouse

Available applications

Enzyme Immunoassay (E), Paraffin Sections (P), Western blot / Immunoblot (WB), Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of CDNF antibody

The conserved dopamine neurotrophic factor (CDNF) is a neurotrophic factor for dopaminergic neurons and highly homologous to the mesencephalic-astrocyte-derived neuro-trophic factor. Somewhat surprisingly, CDCF is expressed at higher levels in tissues such as heart, skeletal muscle and testes than in brain. Similar to the glial cell line-derived neurotrophic factor (GDNF), CDNF can prevent the 6-hydroxylamine (6-OHDA)-induced degeneration of dopaminergic neurons in a rat model of Parkinson's disease. Furthermore, CDNF was able to restore the dopaminergic function and prevent the degeneration of dopaminergic neurons in the substantia nigra, suggesting that CDNF might be suitable for the treatment of Parkinson's disease. At least two isoforms of CDNF are known to exist. This antibody does not cross-react with MANF.

17 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CDNF (C-term) antibody

Western blot analysis of CDNF in mouse brain tissue lysate with CDNF antibody at (A) 2 and (B) 4 ug/ml. Rabbit IgG Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CDNF (N-term) antibody

Western blot analysis of CDNF in A-20 cell lysate in (A) the absence and (B) the presence of blocking peptide with CDNF antibody at 1 ug/ml. Rabbit IgG Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CDNF antibody

WB Suggested Anti-CDNF Antibody; Titration: 1.0 ug/ml; Positive Control: Hela Whole cell Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

CDNF antibody

ELISA: CDNF Antibody Rabbit IgG Purified Hu E
0.1 mg / €325.00
  OriGene Technologies, Inc.

CDNF antibody

Immunofluorescence detection of human CDNF expressed in U2OS cells. CDNF was visualized using anti-CDNF antibody clone 7D6 at 1 µg/ml.  Goat ant-mouse AlexaFluor488 was used as secondary antibody. For nuclear staining DAPI was used. ArrayScan VTI platform (Thermo Scientific) was used for image acquisition (10x objective). Composite picture was generated using pseudocolors green for CDNF specific signal and blue for nuclei. A. CDNF-expressing U2OS cells; B. Negative control. Mouse IgG1 7D6 Aff - Purified Hu, Ms E, ICC/IF, WB
0.1 mg / €400.00
  Acris Antibodies GmbH

CDNF antibody

Immunohistochemistry testing of anti-CDNF monoclonal antibody 6G5. Analysis was performed using formalin-fixed paraffin-embedded human cerebral cortex tissue sections from Alzheimer’s disease patients. Tissue sections were boiled with sodium citrate buffer (pH 6) for antigen retrieval. Incubation with primary antibody at 5 μg/ml was performed overnight at 4°C. DAKO EnVision<sup>TM</sup> Detection System, Peroxidase/DAB was used for visualization. Sections were counterstained with toluidine blue and mounted with Eukitt mounting medium. <strong>A.</strong> CDNF staining by monoclonal antibody 6G5; <strong>B.</strong> Negative staining without primary antibody. Mouse IgG1 7G5 Aff - Purified Hu E, ICC/IF, P, WB
0.1 mg / €400.00
  Acris Antibodies GmbH

CDNF antibody

Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit IgG Aff - Purified Hu, Ms, Rt C, E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

CDNF Control Peptide

CDNF
50 µg / €160.00
  Acris Antibodies GmbH

CDNF Control Peptide

CDNF
50 µg / €160.00
  Acris Antibodies GmbH

CDNF antibody

Immunohistochemistry testing of anti-CDNF Rabbit polyclonal antibody. Analysis was performed using formalin-fixed paraffin-embedded human cerebral cortex tissue sections from Alzheimer’s disease patients. Tissue sections were boiled with sodium citrate buffer (pH 6) for antigen retrieval. Incubation with primary antibody at 5 μg/ml was performed overnight at 4°C. DAKO EnVisionTM Detection System, Peroxidase/DAB was used for visualization. Sections were counterstained with toluidine blue and mounted with Eukitt mounting medium. A. CDNF staining by rabbit polyclonal anti-CDNF antibody; B. Negative staining without primary antibody. Rabbit IgG Aff - Purified Hu, Ms E, ICC/IF, P, WB
0.1 mg / €400.00
  Acris Antibodies GmbH

CDNF (C-term) antibody

Immunohistochemistry of ARMETL1 in human brain tissue with ARMETL1 polyclonal antibody ( Cat # PAB13299 ) at 2.5 µg/ml. Rabbit Hu, Ms, Rt P, WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

CDNF (N-term) antibody

Immunohistochemistry of ARMETL1 in human brain tissue with ARMETL1 polyclonal antibody ( Cat # PAB13300 ) at 5 µg/ml. Rabbit Hu, Ms, Rt P, WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

CDNF antibody

ELISA: CDNF Antibody [26150002] Rabbit Hu E
50 µg / €440.00
  Novus Biologicals Inc.

CDNF antibody

Immunohistochemistry-Paraffin: CDNF Antibody [NBP1-76834] - Human brain tissue with CDNF antibody at 2.5 ug/mL._x000d_ Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

CDNF antibody

Immunohistochemistry-Paraffin: CDNF Antibody [NBP1-76835] - Human brain tissue with CDNF antibody at 5 ug/mL._x000d_ Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

CDNF antibody

Immunohistochemistry-Paraffin: CDNF Antibody [NBP1-88994] - Immunohistochemical staining of human liver shows strong cytoplasmic positivity in hepatocytes. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Lysates

Catalog No.    

CDNF overexpression lysate

CDNF overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

17 Item(s)

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