CDS1 antibody

Principal name

CDS1 antibody

Alternative names for CDS1 antibody

CDP-DG synthetase 1, CDP-DAG synthase 1, Phosphatidate cytidylyltransferase 1, CDP-diglyceride pyrophosphorylase 1, CDP-diglyceride synthetase 1, CDP-diacylglycerol synthase 1, CTP:phosphatidate cytidylyltransferase 1

SwissProt ID

O35052 (Rat), P98191 (Mouse), Q92903 (Human)

Gene ID

1040 (CDS1), 74596 (Cds1), 81925

Available reactivities

Hu (Human), Ms (Mouse), Por (Porcine), Rt (Rat), Bov (Bovine), Can (Canine), Rb (Rabbit)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB)

Background of CDS1 antibody

Breakdown products of phosphoinositides are ubiquitous second messengers that function downstream of many G protein-coupled receptors and tyrosine kinases regulating cell growth, calcium metabolism, and protein kinase C activity. CDS1 is an enzyme which regulates the amount of phosphatidylinositol available for signaling by catalyzing the conversion of phosphatidic acid to CDP-diacylglycerol. This enzyme is an integral membrane protein localized to two subcellular domains, the matrix side of the inner mitochondrial membrane where it is thought to be involved in the synthesis of phosphatidylglycerol and cardiolipin and the cytoplasmic side of the endoplasmic reticulum where it functions in phosphatidylinositol biosynthesis.Breakdown products of phosphoinositides are ubiquitous second messengers that function downstream of many G protein-coupled receptors and tyrosine kinases regulating cell growth, calcium metabolism, and protein kinase C activity. This gene encodes an enzyme which regulates the amount of phosphatidylinositol available for signaling by catalyzing the conversion of phosphatidic acid to CDP-diacylglycerol. This enzyme is an integral membrane protein localized to two subcellular domains, the matrix side of the inner mitochondrial membrane where it is thought to be involved in the synthesis of phosphatidylglycerol and cardiolipin and the cytoplasmic side of the endoplasmic reticulum where it functions in phosphatidylinositol biosynthesis. Two genes encoding this enzyme have been identified in humans, one mapping to human chromosome 4q21 and a second to 20p13.

General readings

"The role of CDP-diacylglycerol synthetase and phosphatidylinositol synthase activity levels in the regulation of cellular phosphatidylinositol content." Lykidis A., Jackson P.D., Rock C.O., Jackowski S. J. Biol. Chem. 272:33402-33409(1997) [PubMed: 9407135]

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CDS1 (N-term) antibody

Human Jurkat; WB Suggested Anti-CDS1 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:62500. Positive Control: Jurkat cell lysate; CDS1 antibody - N-terminal region (AP46043PU-N) in Human Jurkat cells using Western Blot Rabbit Aff - Purified Bov, Can, Hu, Ms, Por, Rb, Rt WB
50 µg / €350.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

CDS1 - human gene knockout kit via CRISPR

CDS1 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

CDS1 - human gene knockout kit via CRISPR

CDS1 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

CDS1 - human gene knockout kit via CRISPR

CDS1 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

CDS1 - human gene knockout kit via CRISPR

CDS1 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Cds1 - mouse gene knockout kit via CRISPR

Cds1 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Cds1 - mouse gene knockout kit via CRISPR

Cds1 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Cds1 - mouse gene knockout kit via CRISPR

Cds1 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Cds1 - mouse gene knockout kit via CRISPR

Cds1 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Cds1 (GFP-tagged ORF) - Rat CDP-diacylglycerol synthase 1 (Cds1), 200 uL, >10^7 TU/mL

Lenti ORF particles, Cds1 (GFP-tagged ORF) - Rat CDP-diacylglycerol synthase 1 (Cds1), 200 uL, >10^7 TU/mL  
200 µl / €1,070.00
  OriGene Technologies, Inc.

Lenti ORF particles, Cds1 (Myc-DDK-tagged ORF) - Rat CDP-diacylglycerol synthase 1 (Cds1), 200 uL, >10^7 TU/mL

Lenti ORF particles, Cds1 (Myc-DDK-tagged ORF) - Rat CDP-diacylglycerol synthase 1 (Cds1), 200 uL, >10^7 TU/mL  
200 µl / €954.00
  OriGene Technologies, Inc.

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