CDw293 / BMPR1B antibody

Principal name

CDw293 / BMPR1B antibody

Alternative names for CDw293 / BMPR1B antibody

ALK6, Bone morphogenetic protein receptor type-1B

SwissProt ID

O00238 (Human), P36898 (Mouse), Q05438 (Chick)

Gene ID

658 (BMPR1B), 12167 (Bmpr1b)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection)), Immunoprecipitation (IP), Enzyme Immunoassay (E)

Background of CDw293 / BMPR1B antibody

BMPR1B (Bone Morphogenetic Protein Receptor Type IB), also known as ALK6, is a protein which in humans is encoded by the BMPR1B gene. BMPR1B is a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. By analysis of a monochromosome hybrid mapping panel and by FISH, Astrom et al. (1999) mapped the BMPR1B gene to chromosome 4q22-q24. Ide et al. (1997) compared BMP receptor expression in normal and cancerous prostate tissues. While BMPR1A and BMPR2 were expressed at similar levels in all prostate tissues, BMPR1B was expressed at a significantly reduced level in cancerous prostate tissue.

General readings

Ide H., et al. (1997) Oncogene 14:1377-1382.Greenman C., et al. (2007) Nature 446:153-158.

20 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CDw293 / BMPR1B antibody

  BMPR1B Rabbit Polyclonal Antibody  
Western blot analysis of extracts of mouse brain cell lines, using BMPR1B antibody. Rabbit IgG Purified Hu, Ms
0.1 mg / €325.00
  OriGene Technologies, Inc.

CDw293 / BMPR1B (N-term) antibody

Western blot analysis of anti-BMPR1B Pab in NCI-H460 cell lysate (Lane A) and mouse heart tissue lysate (Lane B). BMPR1B (arrow) was detected using purified Pab. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence. Rabbit Ig Purified Hu, Ms WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CDw293 / BMPR1B (C-term) antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. Rabbit Ig Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CDw293 / BMPR1B (N-term) antibody

Western blot analysis of anti-BMPR1B Pab in NCI-H460 cell lysate (Lane A) and mouse heart tissue lysate (Lane B). BMPR1B (arrow) was detected using purified Pab. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence. Rabbit Ig Purified Hu, Ms WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CDw293 / BMPR1B (Center) antibody

BMPR1B Antibody (Center) (Cat. #AP50380PU-N)immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of BMPR1B Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated. Rabbit Ig Aff - Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

BMPR1B - human gene knockout kit via CRISPR

BMPR1B - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

BMPR1B - human gene knockout kit via CRISPR

BMPR1B - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

BMPR1B - human gene knockout kit via CRISPR

BMPR1B - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

BMPR1B - human gene knockout kit via CRISPR

BMPR1B - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Bmpr1b - mouse gene knockout kit via CRISPR

Bmpr1b - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Bmpr1b - mouse gene knockout kit via CRISPR

Bmpr1b - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Bmpr1b - mouse gene knockout kit via CRISPR

Bmpr1b - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Bmpr1b - mouse gene knockout kit via CRISPR

Bmpr1b - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

CDw293 / BMPR1B (14-126, His-tag)

CDw293 / BMPR1B Human Purified > 80 % by SDS - PAGE E. coli
0.1 mg / €730.00
  Acris Antibodies GmbH

CDw293 / BMPR1B (14-126, His-tag)

CDw293 / BMPR1B Human Purified > 80 % by SDS - PAGE E. coli
20 µg / €300.00
  Acris Antibodies GmbH

Lysates

Catalog No.    

BMPR1B overexpression lysate

BMPR1B overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, BMPR1B (mGFP-tagged) - Human bone morphogenetic protein receptor, type IB (BMPR1B), 200 uL, >10^7 TU/mL

Lenti ORF particles, BMPR1B (mGFP-tagged) - Human bone morphogenetic protein receptor, type IB (BMPR1B), 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, BMPR1B (Myc-DDK tagged) - Human bone morphogenetic protein receptor, type IB (BMPR1B) , 200 uL, >10^7 TU/mL

Lenti ORF particles, BMPR1B (Myc-DDK tagged) - Human bone morphogenetic protein receptor, type IB (BMPR1B) , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Bmpr1b (GFP-tagged) - Mouse bone morphogenetic protein receptor, type 1B (Bmpr1b), 200 uL, >10^7 TU/mL

Lenti ORF particles, Bmpr1b (GFP-tagged) - Mouse bone morphogenetic protein receptor, type 1B (Bmpr1b), 200 uL, >10^7 TU/mL  
200 µl / €1,120.00
  OriGene Technologies, Inc.

Lenti ORF particles, Bmpr1b (Myc-DDK-tagged) - Mouse bone morphogenetic protein receptor, type 1B (Bmpr1b), 200 uL, >10^7 TU/mL

Lenti ORF particles, Bmpr1b (Myc-DDK-tagged) - Mouse bone morphogenetic protein receptor, type 1B (Bmpr1b), 200 uL, >10^7 TU/mL  
200 µl / €1,000.00
  OriGene Technologies, Inc.

20 Item(s)

per page
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