CDw293 / BMPR1B antibody

Principal name

CDw293 / BMPR1B antibody

Alternative names for CDw293 / BMPR1B antibody

ALK6, Bone morphogenetic protein receptor type-1B

SwissProt ID

O00238 (Human), P36898 (Mouse), Q05438 (Chick)

Gene ID

658 (BMPR1B)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection)), Immunoprecipitation (IP), Frozen Sections (C), Flow Cytometry (F)

Background of CDw293 / BMPR1B antibody

On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP7/OP-1 and GDF5.Involvement in disease; Defects in BMPR1B are the cause of acromesomelic chondrodysplasia with genital anomalies (AMDGA). Acromesomelic chondrodysplasias are rare hereditary skeletal disorders characterized by short stature, very short limbs, and hand/foot malformations. The severity of limb abnormalities increases from proximal to distal with profoundly affected hands and feet showing brachydactyly and/or rudimentary fingers (knob-like fingers).Defects in BMPR1B are a cause of brachydactyly type A2 (BDA2) [MIM:112600]. Brachydactylies (BDs) are a group of inherited malformations characterized by shortening of the digits due to abnormal development of the phalanges and/or the metacarpals. They have been classified on an anatomic and genetic basis into five groups, A to E, including three subgroups (A1 to A3) that usually manifest as autosomal dominant traits. BDA2 was described first in a large Norwegian kindred. BDA2 is caused by mutations in BMPR1B gene and studies demonstrate that these mutations function as dominant negatives in vitro and in vivo.

General readings

Ide H., et al. (1997) Oncogene 14:1377-1382.Greenman C., et al. (2007) Nature 446:153-158.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CDw293 / BMPR1B antibody

Western blot analysis of extracts of mouse brain cell lines, using BMPR1B antibody. Rabbit IgG Purified Hu, Ms
0.1 mg / €325.00
  OriGene Technologies, Inc.

CDw293 / BMPR1B (N-term) antibody

Western blot analysis of anti-BMPR1B Pab in NCI-H460 cell lysate (Lane A) and mouse heart tissue lysate (Lane B). BMPR1B (arrow) was detected using purified Pab. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence. Rabbit Ig Purified Hu, Ms WB

Regular Price: 0.4 ml / €370.00

Special Price: 0.4 ml / €231.00

  Acris Antibodies GmbH

CDw293 / BMPR1B (C-term) antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. Rabbit Ig Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CDw293 / BMPR1B (N-term) antibody

Western blot analysis of anti-BMPR1B Pab in NCI-H460 cell lysate (Lane A) and mouse heart tissue lysate (Lane B). BMPR1B (arrow) was detected using purified Pab. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence. Rabbit Ig Purified Hu, Ms WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CDw293 / BMPR1B (Center) antibody

BMPR1B Antibody (Center) (Cat. #AP50380PU-N)immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of BMPR1B Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated. Rabbit Ig Aff - Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CDw293 / BMPR1B antibody

Western Blot analysis of BMPR1B expression in transfected 293T cell line (H00000658-T01) by BMPR1B MaxPab polyclonal antibody.

Lane 1: BMPR1B transfected lysate(55.22 KDa).
Lane 2: Non-transfected lysate. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

CDw293 / BMPR1B antibody

Western Blot analysis of BMPR1B expression in transfected 293T cell line (H00000658-T01) by BMPR1B MaxPab polyclonal antibody.

Lane 1: BMPR1B transfected lysate(55.22 KDa).
Lane 2: Non-transfected lysate. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

CDw293 / BMPR1B antibody

Immunoprecipitation of BMPR1B transfected lysate using anti-BMPR1B MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with BMPR1B MaxPab mouse polyclonal antibody (B01) (H00000658-B01). Rabbit Serum Hu E(detection), IP
0.1 ml / €380.00
  Abnova Taiwan Corp.

CDw293 / BMPR1B antibody

Western Blot analysis of BMPR1B expression in transfected 293T cell line by BMPR1B monoclonal antibody (M01), clone 2F3.

Lane 1: BMPR1B transfected lysate(56.9 KDa).
Lane 2: Non-transfected lysate. Mouse IgG1 2F3 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

CDw293 / BMPR1B antibody

Western Blot analysis of BMPR1B expression in transfected 293T cell line by BMPR1B monoclonal antibody (M02), clone 3A8.

Lane 1: BMPR1B transfected lysate(57 KDa).
Lane 2: Non-transfected lysate. Mouse IgG1 3A8 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

CDw293 / BMPR1B antibody

BMPR1B monoclonal antibody (M07), clone 2E2. Western Blot analysis of BMPR1B expression in HeLa ( Cat # L013V1 ). Mouse IgG2a 2E2 Purified Hu, Ms E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

CDw293 / BMPR1B antibody

Western blot analysis of BMPR1B polyclonal antibody ( Cat # PAB3837 ) in NCI-H460 cell lysate ( Lane A ) and mouse heart tissue lysate ( Lane B ) . BMPR1B ( arrow ) was detected using purified polyclonal antibody. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence. Rabbit Hu, Ms E, WB
0.4 ml / €390.00
  Abnova Taiwan Corp.

CDw293 / BMPR1B antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with BMPR1B polyclonal antibody ( Cat # PAB3838 ) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma. Rabbit Hu E, P, WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

CDw293 / BMPR1B antibody

Western blot analysis of BMPR1B polyclonal antibody ( Cat # PAB3839 ) in NCI-H460 cell lysate ( Lane A ) and mouse heart tissue lysate ( Lane B ) . BMPR1B ( arrow ) was detected using purified polyclonal antibody. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence. Rabbit Hu, Ms E, WB
0.4 ml / €390.00
  Abnova Taiwan Corp.

CDw293 / BMPR1B antibody

CDw293 / BMPR1B Rabbit IgG Aff - Purified Hu, Ms, Rt WB
0.1 mg / €290.00
  Boster Immunoleader

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

CDw293 / BMPR1B (14-126, His-tag)

CDw293 / BMPR1B Human Purified > 80 % by SDS - PAGE E. coli
0.1 mg / €730.00
  Acris Antibodies GmbH

CDw293 / BMPR1B (14-126, His-tag)

CDw293 / BMPR1B Human Purified > 80 % by SDS - PAGE E. coli
20 µg / €300.00
  Acris Antibodies GmbH

CDw293 / BMPR1B

CDw293 / BMPR1B Human
10 µg / €540.00
  Abnova Taiwan Corp.

CDw293 / BMPR1B

CDw293 / BMPR1B Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

CDw293 / BMPR1B

CDw293 / BMPR1B Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

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