Cdx2 antibody

Principal name

Cdx2 antibody

Alternative names for Cdx2 antibody

Homeobox protein CDX-2, CDX-3, CDX3, Caudal-type homeobox protein 2

SwissProt ID

P43241 (Mouse), Q99626 (Human)

Gene ID

1045 (CDX2)

Available reactivities

Hu (Human), Can (Canine), Ms (Mouse), Rt (Rat), Chk (Chicken), Por (Porcine)

Available hosts

Rabbit, Mouse, Goat

Available applications

Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Western blot / Immunoblot (WB), Flow Cytometry (F), Enzyme Immunoassay (E), Immunoprecipitation (IP)

Background of Cdx2 antibody

The caudal type homeo box transcription factors 1 (CDX1) and 2 (CDX2) are candidates for directing intestinal development, differentiation, and maintenance of the intestinal phenotype. CDX1 and CDX2 expression is widely present in the human intestinal and colonic mucosae, but not in the gastric mucosa, suggesting a possible role in the terminal differentiation of the intestine. Increased CDX2 expression is associated with chronic atrophic gastritis. Detectable expression of CDX2 precedes expression of CDX1 during the progression of intestinal metaplasia, thus expression of CDX2 may trigger the initiation and development of intestinal metaplasia. Markedly reduced or absent CDX2 expression was noted by immunohistochemistry in 13 of 15 (87%) large cell minimally differentiated carcinomas (LCMDCs), whereas only 1 of the 25 (4%) differentiated adenocarcinomas (DACs) showed reduced CDX2 expression. Thus, a significant decrease in human CDX1 and/or CDX2 expression may be associated with colorectal tumorigenesis.

General readings

Bai et al. Cancer Letter 176: 47, 2002
Hinoi et al. Am J Pathol 159: 2239, 2001
Silberg et al. Gastroenterology 119: 961, 2000

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Cdx2 antibody

Human Small intestine: Formalin-Fixed, Paraffin-Embedded (FFPE) Mouse 1C7 Hu E, P, WB
50 µg / €530.00
  Acris Antibodies GmbH

Cdx2 antibody

Immunoperoxidase of monoclonal antibody to CDX2 on formalin-fixed paraffin-embedded human small Intestine. [antibody concentration 3 ug/ml] Mouse IgG 1C7 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Cdx2 antibody

Human Colon Carcinoma stained with anti-CDX2 Antibody Cat.-No AM11120PU (Clone SP54). Rabbit SP54 Purified Hu F, P
1 ml / €750.00
  Acris Antibodies GmbH

Cdx2 antibody

Human Colon Carcinoma stained with anti-CDX2 Antibody Cat.-No AM11120PU (Clone SP54). Rabbit SP54 Purified Hu F, P

Regular Price: 0.2 ml / €250.00

Special Price: 0.2 ml / €175.00

  Acris Antibodies GmbH

Cdx2 antibody

Human Colon Carcinoma stained with anti-CDX2 Antibody Cat.-No AM11120PU (Clone SP54). Rabbit SP54 Purified Hu F, P

Regular Price: 50 µl / €80.00

Special Price: 50 µl / €56.00

  Acris Antibodies GmbH

Cdx2 antibody

TA303095 (1µg/ml) staining of Human Kidney lysate (35µg protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Can, Hu, Ms, Rt E, WB
20 µg / €200.00
  Acris Antibodies GmbH

Cdx2 (N-term) antibody

Western blot analysis of CDX2(arrow) using rabbit polyclonal CDX2 Antibody (N-term)(Cat. #TA302103). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the CDX2 gene (Lane 2) (Origene Technologies). Rabbit Ig Purified Hu P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Cdx2 antibody

TA303095 (1µg/ml) staining of Human Kidney lysate (35µg protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Can, Hu, Ms, Rt E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Cdx2 antibody

Predicted band size: 34 kDa . Positive control: HT-29, MCF-7, COS-7 and C2C12 cells lysate. Recommended dilution: 1/ 500-1000. (Gel: 10%SDS-PAGE Lane1,2,3,4: HT-29, MCF-7, COS-7 and C2C12 cells lysate Lysates: 30 ug per lane Primary antibody: 1/500 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute) Rabbit IgG Purified Hu, Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Cdx2 antibody

Western blot analysis of extracts from K562 cells, using CDX2 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Cdx2 antibody

Western blot analysis of extracts from rat heart cells, using CDX2 (Ab-283) antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Cdx2 antibody

Immunohistochemistry staining of Paraffin Colon tissue by CDX2 antibody (dilution: 1:100 - 1:500; visualization of staining: Nuclear) Rabbit IgG EPR2764Y Purified Hu P
1 ml / €380.00
  OriGene Technologies, Inc.

Cdx2 antibody

Western blot detection of CDX2 in Hela,Caco2,C2C12,SW480,COS7,HepG2 and 3T3 cell lysates using CDX2 mouse mAb (1:1000 diluted).Predicted band size:34KDa.Observed band size:34KDa. Mouse 4B9-B12-E9 Purified ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Cdx2 antibody

Western blot detection of CDX2 in Hela,COS7 and K562 cell lysates using CDX2 mouse mAb (1:1000 diluted).Predicted band size:34KDa.Observed band size:34KDa. Mouse IgG1 4F12-B3-H4 Purified ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Cdx2 antibody

Western blot analysis of extracts from HT-29, MCF-7, COS-7 and C2C12 cells using Cdx2 Antibody Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Cdx2 antibody

Western blot analysis of CDX2 in mouse brain tissue lysate with CDX2 antibody at 1 ug/mL. Rabbit IgG Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Cdx2 antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CDX2 (RC204883, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CDX2. Mouse IgG2a OTI1A3 Purified Can, Hu WB
0.1 ml / €379.00
  OriGene Technologies, Inc.

TrueMAB

Cdx2 antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CDX2 (RC204883, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CDX2. Mouse IgG2a OTI3G4 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Cdx2 antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CDX2 (RC204883, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CDX2. Mouse IgG1 OTI2G1 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Cdx2 antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CDX2 (RC204883, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CDX2. Mouse IgG2a OTI5A1 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

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