CEACAM7 antibody

Principal name

CEACAM7 antibody

Alternative names for CEACAM7 antibody

CGM2, Carcinoembryonic antigen-related cell adhesion molecule 7, Carcinoembryonic antigen CGM2

SwissProt ID

Q14002 (Human)

Gene ID

1087 (CEACAM7)

Available reactivities

Hu (Human), Bov (Bovine), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit), Rt (Rat)

Available hosts

Mouse, Rabbit, Chicken

Available applications

Enzyme Immunoassay (E), Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF), Flow Cytometry (F), Western blot / Immunoblot (WB)

Background of CEACAM7 antibody

CEA-related cell adhesion molecule 7 (CEACAM7, CGM2) belongs to the carcinoembryonic antigen (CEA) family (1). It encodes a glycosyl phosphatidyl inositol (GPI)-linked glycoprotein which is only found on the apical surface of highly differentiated epithelial cells adult colon and on a small epithelial cell population in pancreatic ducts (2). CEACAM7 expression is completely lost upon malignant transformation already in hyperplastic polyps and early adenomas as well as in adenocarcinomas of the colon (2). Like all members of the CEACAM family, it consists of a single N domain, with structural homology to the immunoglobulin variable domains, followed by one immunoglobulin constant-like A domain.

General readings

Thompson J, Seitz M, et al. (1997). Cancer Res. 57(9):1776-84.Kinugasa T, Kuroki M, et al. (1998). Int J Cancer. 76(1):148-53.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CEACAM7 antibody

Figure 2. Members of the CEACAM family were expressed on BOSC cells after transient transfection withexpression vectors containing either the cDNA of CEACAM1, 5, 6, 7, 8 or a recombinant trans-membrane-anchored PSG1 fusion protein. 
Recognition of CEACAM3, CEACAM4 and PSG1 was tested on stably transfected HeLa (CEACAM3, PSG) and CHO cells (CEACAM4), respectively. 
Expression of the con-structs was confirmed with monoclonal antibodies known to recognize the corresponding proteins (CEACAM1, 3, 4, 5 and 6: D14HD11; CEACAM7: CAC2; CEACAM8: TET2; PSG: BAP1; green curves). An irrelevant monoclonal antibody served as a negative control (black curves). 
For specificity testing, protein G purified BAC2 was tested on all CEACAM transfectants. 
A positive signal was only obtained with CEACAM7 expressing cells (Red curves). Mouse IgG1 BAC2 Purified Hu C, E, F, ICC/IF
0.1 mg / €330.00
  Acris Antibodies GmbH

CEACAM7 antibody

WB Suggested Anti-CEACAM7 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:62500; Positive Control: Jurkat cell lysate Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

CEACAM7 antibody

WB Suggested Anti-CEACAM7 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:62500; Positive Control: Hela cell lysate Rabbit IgG Purified Bov, Eq, GP, Hu, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

CEACAM7 (N-term) antibody

CEACAM7 Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

CEACAM7 (C-term) antibody

Human HeLa; WB Suggested Anti-CEACAM7 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:62500. Positive Control: Hela cell lysate; CEACAM7 antibody - C-terminal region (ARP60123_P050) in Human HeLa cells using Western Blot Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

CEACAM7 antibody

CEACAM7 Rabbit Aff - Purified Hu WB
50 µg / €440.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

CEACAM7

CEACAM7 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

CEACAM7 (36-242, His-tag)

CEACAM7 Human Purified > 85 % by SDS - PAGE E. coli
0.25 mg / €940.00
  Acris Antibodies GmbH

CEACAM7 (36-242, His-tag)

CEACAM7 Human Purified > 85 % by SDS - PAGE E. coli
50 µg / €370.00
  Acris Antibodies GmbH

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