CENP-A antibody

Principal name

CENP-A antibody

Alternative names for CENP-A antibody

Centromere protein A, CENPA, Histone H3-like centromeric protein A, Centromere autoantigen A

SwissProt ID

O35216 (Mouse), P49449 (Bovin), P49450 (Human), Q569M3 (Xenla), Q6XXM1 (Chick)

Gene ID

1058 (CENPA)

Available reactivities

Hu (Human), Bov (Bovine), Ms (Mouse), Rt (Rat), Ze (Zebrafish), Pl (Plant), Can (Canine), Eq (Equine), GP (Guinea Pig), Gt (Goat), Rb (Rabbit)

Available hosts

Mouse, Rabbit, Goat

Available applications

Immunocytochemistry/Immunofluorescence (ICC/IF), Frozen Sections (C), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Flow Cytometry (F), Paraffin Sections (P), Immunoprecipitation (IP)

Background of CENP-A antibody

Histones are highly conserved proteins that serve as the structural scaffold for the organization of nuclear DNA into chromatin. The four core histones, H2A, H2B, H3, and H4, assemble into an octamer (2 molecules of each). Subsequently, 146 base pairs of DNA are wrapped around the octamer, forming a nucleosome, the basic subunit of chromatin. Histone modifications regulate DNA transcription, repair, recombination, and replication. The most commonly studied modifications are acetylation, phosphorylation, methylation, and ubiquitination. These modifications can alter local chromatin architecture, or recruit trans-acting factors that recognize specific histone modifications (the "histone code" hypothesis). Trimethylation of histone H3 on Lys9 (H3K9me3) is one of the most highly studied epigenetic marks. H3K9me3 functions in the repression of euchromatic genes, and in epigenetic control of heterochromatin assembly, most likely via acting as a recognition motif for the binding of chromatin-associated proteins, such as Swi6 or HP1Alpha/Beta. The enzymes responsible for H3K9me3 formation are SUV39H1 and SUV39H2.

General readings

Black,B.E., (2004) Nature 430 (6999), 578-582

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CENP-A antibody

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using CENPA antibody.The picture on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

CENP-A antibody

Western blot analysis of CENP-A in U2OS lysates using a 1:1000 dilution of the antibody Mouse IgG1 5A7-2E11 Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CENP-A antibody

WB Suggested Anti-CENPA Antibody Titration: 1.25 ug/ml; Positive Control: Jurkat cell lysate.CENPA is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells Rabbit IgG Purified Hu, Ms, Rt P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CENP-A antibody

WB Suggested Anti-CENPA Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 62500; Positive Control: Hela cell lysate.CENPA is strongly supported by BioGPS gene expression data to be expressed in HeLa Rabbit IgG Purified Bov, Can, Eq, GP, Gt, Hu, Ms, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

CENP-A (130-140) antibody

Human Lung: Formalin-Fixed, Paraffin-Embedded (FFPE) Goat IgG Aff - Purified Bear, Bov, Can, Elephant, Eq, Fi, Hst, Hu, L, Mky, Op, Platypus, Por, Prim, Rb, Rt, Xen P
50 µg / €470.00
  Acris Antibodies GmbH

CENP-A antibody

CENP-A Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

CENP-A antibody

Detection limit for recombinant GST tagged CENPA is approximately 0.3ng/ml as a capture antibody. Mouse IgG1 1D4-1A3 Purified Hu E
0.1 mg / €370.00
  Abnova Taiwan Corp.

CENP-A pSer7 antibody

Immunofluorescence analysis of HeLa cells, using Centromeric Protein A (Phospho-Ser7) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit IgG Aff - Purified Hu E, ICC/IF
50 µg / €205.00
  Assay Biotech

CENP-A pSer7 antibody

Immunofluorescence analysis of HeLa cells, using Centromeric Protein A (Phospho-Ser7) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit IgG Aff - Purified Hu E, ICC/IF
0.1 mg / €310.00
  Assay Biotech

CENP-A antibody

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using Centromeric Protein A (Ab-7) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, ICC/IF
50 µg / €205.00
  Assay Biotech

CENP-A antibody

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using Centromeric Protein A (Ab-7) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, ICC/IF
0.1 mg / €310.00
  Assay Biotech

CENP-A antibody

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using CENPA Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, P
50 µg / €205.00
  Assay Biotech

CENP-A antibody

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using CENPA Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, P
0.1 mg / €310.00
  Assay Biotech

CENP-A antibody

Human Skin; CENPA antibody - N-terminal region (ARP46040_T100) in Human Skin cells using Immunohistochemistry Rabbit Aff - Purified Hu P, WB
0.1 mg / €310.00
  AVIVA Systems Biology

CENP-A antibody

Human 721_B; Host:Rabbit. Target Name:CENPA. Sample Tissue:721_B. Antibody Dilution: 1.0ug/ml. CENPA is strongly supported by BioGPS gene expression data to be expressed in Human 721_B cells.; CENPA antibody - middle region (ARP46041_P050) in Human 721_B cells using Western Blot Rabbit Aff - Purified Bov, Hu, Ms, Rt, Ze WB
50 µg / €350.00
  AVIVA Systems Biology

CENP-A (C-term) antibody

Immunofluorescent: CENP-A (C-term) Antibody (EP800Y) [NB110-55716] - Immunofluorescent staining of HeLa cells using anti-CENP-A Rabbit IgG EP800Y Purified Hu F, ICC/IF, P, WB
0.1 ml / €420.00
  Novus Biologicals Inc.

CENP-A antibody

Western Blot: CENPA Antibody [NBP1-52937] - This Anti-CENPA antibody was used in Western Blot of Jurkat tissue lysate at a concentration of 1.25ug/ml. Rabbit Purified Hu P, WB
0.1 mg / €360.00
  Novus Biologicals Inc.

CENP-A antibody

CENP-A Rabbit IgG Aff - Purified Hu E, ICC/IF, P
0.1 mg / €360.00
  Novus Biologicals Inc.

CENP-A antibody

CENP-A Rabbit IgG Aff - Purified Hu E, ICC/IF, P
50 µg / €290.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

CENP-A (transcript variant 2)

CENP-A Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

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