CENP-A antibody

Principal name

CENP-A antibody

Alternative names for CENP-A antibody

Centromere protein A, CENPA, Histone H3-like centromeric protein A, Centromere autoantigen A

SwissProt ID

O35216 (Mouse), P49449 (Bovin), P49450 (Human), Q569M3 (Xenla), Q6XXM1 (Chick)

Gene ID

1058 (CENPA), 12615 (Cenpa)

Available reactivities

Hu (Human), Bov (Bovine), Ms (Mouse), Rt (Rat), Ze (Zebrafish), Can (Canine), Eq (Equine), Fi (Fish), Hst (Hamster), Mky (Monkey), Op (Opossum), Por (Porcine), Prim (Primate), Rb (Rabbit), Xen (Xenopus), L (Lizard), Bear, GP (Guinea Pig), Gt (Goat)

Available hosts

Mouse, Rabbit, Goat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of CENP-A antibody

Centromeres are the differentiated chromosomal domains that specify the mitotic behavior of chromosomes. CENPA is a centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere. CENPA is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces 1 or both copies of conventional histone H3 in the (H3-H4)2 tetrameric core of the nucleosome particle.Centromeres are the differentiated chromosomal domains that specify the mitotic behavior of chromosomes. CENPA encodes a centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere. CENPA is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces 1 or both copies of conventional histone H3 in the (H3-H4)2 tetrameric core of the nucleosome particle.

General readings

Black,B.E., (2004) Nature 430 (6999), 578-582

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Lysates

Catalog No.    

CENPA overexpression lysate

CENPA overexpression lysate  
0.1 mg / €295.00
  OriGene Technologies, Inc.

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