CENP-B antibody

Principal name

CENP-B antibody

Alternative names for CENP-B antibody

Centromere protein B, CENPB, Major centromere autoantigen B

SwissProt ID

P07199 (Human), P27790 (Mouse), P48988 (Crigr), P49451 (Sheep)

Gene ID

1059 (CENPB)

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Ms (Mouse), Rt (Rat), Ze (Zebrafish), Eq (Equine), Por (Porcine), Sh (Sheep), Ye (Yeast)

Available hosts

Mouse, Rabbit

Available applications

ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB)

Background of CENP-B antibody

CENPB is a highly conserved protein that facilitates centromere formation. It is a D-binding protein that is derived from transposases of the pogo D transposon family. It contains a helix-loop-helix D binding motif at the N-terminus, and a dimerization domain at the C-terminus. This protein is proposed to play an important role in the assembly of specific centromere structures in interphase nuclei and on mitotic chromosomes. It is also considered a major centromere autoantigen recognized by sera from patients with anti-centromere antibodies.This gene product is a highly conserved protein that facilitates centromere formation. It is a D-binding protein that is derived from transposases of the pogo D transposon family. It contains a helix-loop-helix D binding motif at the N-terminus, and a dimerization domain at the C-terminus. The D binding domain recognizes and binds a 17-bp sequence (CENP-B box) in the centromeric alpha satellite D. This protein is proposed to play an important role in the assembly of specific centromere structures in interphase nuclei and on mitotic chromosomes. It is also considered a major centromere autoantigen recognized by sera from patients with anti-centromere antibodies. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additiol publications.

9 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CENP-B antibody

  Rabbit Polyclonal Anti-CENPB Antibody  
WB Suggested Anti-CENPB Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 500; Positive Control: Jurkat cell lysate Rabbit IgG Purified Bov, Eq, Hu, Ms, Por, Rt, Sh, Ye, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

CRISPR

Catalog No. Species Donor Vector  

CENPB - human gene knockout kit via CRISPR

CENPB - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

CENPB - human gene knockout kit via CRISPR

CENPB - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

CENPB - human gene knockout kit via CRISPR

CENPB - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

CENPB - human gene knockout kit via CRISPR

CENPB - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

CENP-B

  Recombinant protein of human centromere protein B, 80kDa (CENPB)  
CENP-B Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

Lysates

Catalog No.    

CENPB overexpression lysate

CENPB overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, CENPB (mGFP-tagged)-Human centromere protein B, 80kDa (CENPB), 200 uL, >10^7 TU/mL

Lenti ORF particles, CENPB (mGFP-tagged)-Human centromere protein B, 80kDa (CENPB), 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, CENPB (Myc-DDK-tagged)-Human centromere protein B, 80kDa (CENPB), 200 uL, >10^7 TU/mL

Lenti ORF particles, CENPB (Myc-DDK-tagged)-Human centromere protein B, 80kDa (CENPB), 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

9 Item(s)

per page
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