CENP-F antibody

Principal name

CENP-F antibody

Alternative names for CENP-F antibody

Kinetochore protein CENPF, Mitosin, AH antigen, Centromere protein F

SwissProt ID

P49454 (Human)

Gene ID

1063 (CENPF)

Available reactivities

Hu (Human)

Available hosts

Mouse, Rabbit, Goat

Available applications

Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Western blot / Immunoblot (WB), Paraffin Sections (P), Flow Cytometry (F), Enzyme Immunoassay (E)

Background of CENP-F antibody

Required for kinetochore function and chromosome segregation in mitosis. Required for kinetochore localization of dynein, LIS1, NDE1 and NDEL1. Regulates recycling of the plasma membrane by acting as a link between recycling vesicles and the microtubule network though its association with STX4 and SNAP25. Acts as a potential inhibitor of pocket protein-mediated cellular processes during development by regulating the activity of RB proteins during cell division and proliferation. May play a regulatory or permissive role in the normal embryonic cardiomyocyte cell cycle and in promoting continued mitosis in transformed, abnormally dividing neonatal cardiomyocytes. Interaction with RB directs embryonic stem cells toward a cardiac lineage. Involved in the regulation of DNA synthesis and hence cell cycle progression, via its C-terminus. Has a potential role regulating skeletal myogenesis and in cell differentiation in embryogenesis. Involved in dendritic cell regulation of T-cell immunity against chlamydia.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CENP-F antibody

  Rabbit Polyclonal CENPF Antibody  
Western Blot: CENPF antibody - Detection of CENP-F using anti-CENPF. 25ug of asynchronous and mitotically blocked HeLa lysates were loaded in each respective lane. Lanes 1 & 2 show anti-CENPF applied at 1:2000, and lanes 3 & 4 show anti-CENPF applied at 1:10,000. Rabbit Purified Hu F, ICC/IF, IP, WB
50 µl / €325.00
  OriGene Technologies, Inc.

CENP-F (3198-3210) antibody

Human Kidney (formalin-fixed, paraffin-embedded) stained with CENPF antibody AP22486PU-N at 3.75 µg/ml followed by biotinylated anti-goat IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen. Goat Aff - Purified Hu E, P
50 µg / €470.00
  Acris Antibodies GmbH

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