CENP-R / ITGB3BP antibody

Principal name

CENP-R / ITGB3BP antibody

Alternative names for CENP-R / ITGB3BP antibody

Centromere protein R, CENPR, NRIF3, Beta-3-endonexin, Nuclear receptor-interacting factor 3, Integrin beta-3-binding protein

SwissProt ID

Q13352 (Human), Q1T763 (Chick), Q5U1Z7 (Rat), Q9CQ82 (Mouse), Q9UKB6 (Human)

Gene ID

23421 (ITGB3BP)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Immunoprecipitation (IP), Paraffin Sections (P)

Background of CENP-R / ITGB3BP antibody

ITGB3BP is a transcription coregulator that can have both coactivator and corepressor functions. Isoform 1, but not other isoforms, is involved in the coactivation of nuclear receptors for retinoid X (RXRs) and thyroid hormone (TRs) in a ligand-dependent fashion. ITGB3BP acts as a transcriptional corepressor via its interaction with the NFKB1 NF-kappa-B subunit, possibly by interfering with the transactivation domain of NFKB1. It induces apoptosis in breast cancer cells, but not in other cancer cells, via a caspase-2 mediated pathway that involves mitochondrial membrane permeabilization but does not require other caspases. ITGB3BP may also act as an inhibitor of cyclin A-associated kinase. ITGB3BP may be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex.

General readings

Foltz D R., et al. (2006) Nat Cell Biol. 8:458-469.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CENP-R / ITGB3BP antibody

Immunofluorescence of monoclonal antibody to ITGB3BP on A-431 cell. [antibody concentration 10 ug/ml] Mouse IgG2a 3F6 Purified Hu E, ICC/IF, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

CENP-R / ITGB3BP antibody

Predicted band size: 15 kDa . Positive control: Jurkat and 231 cell lysate. Recommended dilution: 1/200-1000. (Gel: 15%+12%+10%SDS-PAGE Lane1: 231 cell lysate Lane2: 231 cell lysate Lysates: 50 ug per lane Primary antibody: 1/150 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 3 seconds) Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CENP-R / ITGB3BP antibody

Western blot analysis of extracts of various cell lines, using ITGB3BP antibody. Rabbit IgG Purified Hu
0.1 mg / €325.00
  OriGene Technologies, Inc.

CENP-R / ITGB3BP antibody

WB Suggested Anti-ITGB3BP Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 62500; Positive Control: MCF7 cell lysate Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

CENP-R / ITGB3BP antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ITGB3BP (RC200064, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ITGB3BP. Mouse IgG1 OTI4H1 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CENP-R / ITGB3BP antibody

CENP-R / ITGB3BP Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

CENP-R / ITGB3BP antibody

Human MCF-7; WB Suggested Anti-ITGB3BP Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:62500. Positive Control: MCF7 cell lysate; ITGB3BP antibody - N-terminal region (ARP54999_P050) in Human MCF-7 cells using Western Blot Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

CENP-R / ITGB3BP antibody

Western Blot: ITGB3BP Antibody [NBP1-59187] - This Anti-ITGB3BP antibody was used in Western Blot of MCF7 tissue lysate at a concentration of 1ug/ml. Rabbit Aff - Purified Hu WB
50 µg / €440.00
  Novus Biologicals Inc.

CENP-R / ITGB3BP antibody

Immunohistochemistry-Paraffin: ITGB3BP Antibody [NBP1-85687] - Immunohistochemical staining of human colon shows moderate nuclear positivity in glandular cells. Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

CENP-R / ITGB3BP

CENP-R / ITGB3BP Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

CENP-R / ITGB3BP (1-216, His-tag)

CENP-R / ITGB3BP Human Purified > 90 % by SDS - PAGE E. coli
0.1 mg / €730.00
  Acris Antibodies GmbH

CENP-R / ITGB3BP (1-216, His-tag)

CENP-R / ITGB3BP Human Purified > 90 % by SDS - PAGE E. coli
20 µg / €300.00
  Acris Antibodies GmbH

CENP-R / ITGB3BP

CENP-R / ITGB3BP Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

CENP-R / ITGB3BP

CENP-R / ITGB3BP Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

CENP-R / ITGB3BP

CENP-R / ITGB3BP Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

CENP-R / ITGB3BP

CENP-R / ITGB3BP Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

CENP-R / ITGB3BP

CENP-R / ITGB3BP Human Purified
10 µg / €380.00
  Abnova Taiwan Corp.

CENP-R / ITGB3BP

CENP-R / ITGB3BP Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

CENP-R / ITGB3BP

CENP-R / ITGB3BP Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

ITGB3BP overexpression lysate

ITGB3BP overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

20 Item(s)

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