CENP-W antibody

Principal name

CENP-W antibody

Alternative names for CENP-W antibody

C6orf173, CUG2, CENPW, Centromere protein W, Cancer-up-regulated gene 2 protein

SwissProt ID

A1L1L1 (Rat), Q3URR0 (Mouse), Q5EE01 (Human)

Gene ID

387103 (CENPW)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Eq (Equine), GP (Guinea Pig)

Available hosts

Rabbit

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E)

Background of CENP-W antibody

CENPW Antibody: CENPW was initially identified as a gene that was upregulated in multiple cancers, and whose overexpression in mouse fibroblast cells gave rise to distinct cancer-specific phenotypes. It was later found to be a nuclear protein that associated with CENPT, a component of CENPA nucleosome complex in the centromere, and is required for proper kinetochore function. CENPW also specifically interacts with the nucleolar phosphoprotein nucleophosmin, also known as B23 It has been suggested that nucleophosmin functions in the assembly of the kinetochore by interacting with CENPW during interphase. Overexpression of CENPW in the SKOV-3 human ovarian cancer cell line as well as in the zebrafish embryo led to apoptosis, suggesting that high levels of CENPW induces apoptotic cell death.

General readings

Lee S, Gang J, Jeon SB, et al. molecular cloning and functional analysis of a novel oncogene, cancer-upregulated gene 2 (CUG2). Biochem. Biophys. Res. Commun. 2007; 360:633-9.

6 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CENP-W (N-term) antibody

Western blot analysis of CENPW in HeLa cell lysate lysate with CENPW antibody at (A) 0.5 and (B) 1 ug/mL. Rabbit IgG Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CENP-W antibody

WB Suggested Anti-CENPW Antibody Titration: 0.2-1 ug/ml; Positive Control: Hela cell lysate Rabbit IgG Purified Eq, GP, Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

CENP-W (N-term) Control Peptide

CENP-W
50 µg / €160.00
  Acris Antibodies GmbH

CENP-W antibody

Human HeLa; WB Suggested Anti-C6orf173 Antibody Titration: 0.2-1 ug/ml. Positive Control: Hela cell lysate; C6orf173 antibody - N-terminal region (ARP54417_P050) in Human HeLa cells using Western Blot Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

CENP-W antibody

Western Blot: CENPW Antibody [NBP1-70496] - This Anti-C6orf173 antibody was used in Western Blot of Hela tissue lysate at a concentration of 1ug/ml. Rabbit Aff - Purified Hu WB
50 µg / €440.00
  Novus Biologicals Inc.

Lysates

Catalog No.    

CENPW overexpression lysate

CENPW overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

6 Item(s)

per page
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