CES1 / ACAT antibody

Principal name

CES1 / ACAT antibody

Alternative names for CES1 / ACAT antibody

CES2, SES1, Liver carboxylesterase 1, HMSE, Egasyn, hBr1, Acyl coenzyme A:cholesterol acyltransferase, Monocyte/macrophage serine esterase, Serine esterase 1, Brain carboxylesterase hBr1, Triacylglycerol hydrolase, Retinyl ester hydrolase

SwissProt ID

P12337 (Rabit), P23141 (Human), Q29550 (Pig), Q8VCC2 (Mouse)

Gene ID

100736962 (LOC100736962), 1066 (CES1), 12623 (Ces1g)

Available reactivities

Por (Porcine), Hu (Human), Bov (Bovine), Can (Canine), Dros (Drosophila), Ms (Mouse), Rb (Rabbit), Rt (Rat), Eq (Equine), Fe (Feline), Hst (Hamster), Mky (Monkey), Prim (Primate), Bear, GP (Guinea Pig), Ye (Yeast), Ze (Zebrafish)

Available hosts

Rabbit, Goat, Mouse

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection)), Dot blot (Dot), Immunodiffusion (ID), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Radioimmunoassay (R)

Background of CES1 / ACAT antibody

CES1 is one of the enzymes responsible for the hydrolysis of ester- and amide-bond-containing drugs such as cocaine and heroin. They also hydrolize long-chain fatty acid esters and thioesters. This enzyme is known to hydrolyze aromatic and aliphatic esters and is necessary for cellular cholesterol esterification. It may also play a role in detoxification in the lung and/or protection of the central nervous system from ester or amide compounds. Carboxylesterase deficiency may be associated with non-Hodgkin lymphoma or B-cell lymphocytic leukemia.Carboxylesterase 1 is a member of a large multigene family. The enzymes encoded by these genes are responsible for the hydrolysis of ester- and amide-bond-containing drugs such as cocaine and heroin. They also hydrolize long-chain fatty acid esters and thioesters. This enzyme is known to hydrolyze aromatic and aliphatic esters and is necessary for cellular cholesterol esterification. It may also play a role in detoxification in the lung and/or protection of the central nervous system from ester or amide compounds. Carboxylesterase deficiency may be associated with non-Hodgkin lymphoma or B-cell lymphocytic leukemia. Three transcript variants encoding three different isoforms have been found for this gene.Carboxylesterase 1 is a member of a large multigene family. The enzymes encoded by these genes are responsible for the hydrolysis of ester- and amide-bond-containing drugs such as cocaine and heroin. They also hydrolize long-chain fatty acid esters and thioesters. This enzyme is known to hydrolyze aromatic and aliphatic esters and is necessary for cellular cholesterol esterification. It may also play a role in detoxification in the lung and/or protection of the central nervous system from ester or amide compounds. Carboxylesterase deficiency may be associated with non-Hodgkin lymphoma or B-cell lymphocytic leukemia. Three transcript variants encoding three different isoforms have been found for this gene.

General readings

Steinberg GR, Kemp BE, Watt MJ.
Adipocyte triglyceride lipase expression in human obesity.
Am J Physiol Endocrinol Metab. 2007 Oct;293(4):E958-64. Epub 2007 Jul 3.
PMID: 17609260

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CES1 / ACAT antibody

  Goat Polyclonal Antibody against CES1  
TA302448 (0.03µg/ml) staining of Human Liver lysate (35µg protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Hu P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CES1 / ACAT antibody

  Rabbit anti-CES1 Polyclonal Antibody  
Western blot analysis of extracts of various cell lines, using CES1 antibody. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CES1 / ACAT antibody

  Rabbit Polyclonal Anti-CES1 Antibody  
WB Suggested Anti-CES1 Antibody Titration: 1.25 ug/ml; Positive Control: Transfected 293T Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ye, Ze WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CES1 / ACAT (533-544) antibody

Lung: Formalin-Fixed Paraffin-Embedded (FFPE) Goat IgG Aff - Purified Bear, Bov, Eq, Fe, Hst, Hu, Mky, Ms, Prim, Rt E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

CES1 / ACAT antibody

CES1 / ACAT Rabbit IgG Azide Free Por Dot, E, ICC/IF, ID, IP, R, WB
10 mg / €240.00
  Acris Antibodies GmbH

CES1 / ACAT antibody

CES1 / ACAT Rabbit IgG Biotin Por Dot, E, ICC/IF, ID, IP, R, WB
1 ml / €350.00
  Acris Antibodies GmbH

CES1 / ACAT antibody

CES1 / ACAT Rabbit IgG Aff - Purified Por Dot, E, ICC/IF, ID, IP, R, WB
1 mg / €440.00
  Acris Antibodies GmbH

CES1 / ACAT antibody

CES1 / ACAT Rabbit Serum Por E, WB
2 ml / €1,180.00
  Acris Antibodies GmbH

CES1 / ACAT antibody

CES1 / ACAT Rabbit HRP Por E, WB
0.1 mg / €450.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

Ces1g - mouse gene knockout kit via CRISPR

Ces1g - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Ces1g - mouse gene knockout kit via CRISPR

Ces1g - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Ces1g - mouse gene knockout kit via CRISPR

Ces1g - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Ces1g - mouse gene knockout kit via CRISPR

Ces1g - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

CES1 - human gene knockout kit via CRISPR

CES1 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

CES1 - human gene knockout kit via CRISPR

CES1 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

CES1 - human gene knockout kit via CRISPR

CES1 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

CES1 - human gene knockout kit via CRISPR

CES1 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

CES1 / ACAT (transcript variant 2)

  Recombinant protein of human carboxylesterase 1 (monocyte/macrophage serine esterase 1) (CES1), transcript variant 2  
CES1 / ACAT Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

CES1 / ACAT (transcript variant 3)

  Recombinant protein of human carboxylesterase 1 (monocyte/macrophage serine esterase 1) (CES1), transcript variant 3  
CES1 / ACAT Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

CES1 / ACAT (transcript variant 1)

  Recombinant protein of human carboxylesterase 1 (monocyte/macrophage serine esterase 1) (CES1), transcript variant 1  
CES1 / ACAT Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

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