CGK1 antibody

Principal name

CGK1 antibody

Alternative names for CGK1 antibody

PRKG1, PRKGR1A, PRKGR1B, CKG1A, CKG1B, PKG, PGK, cGKI-alpha, cGMP-dependent protein kinase 1

SwissProt ID

O77676 (Rabit), P00516 (Bovin), P0C605 (Mouse), Q13976 (Human)

Gene ID

5592 (PRKG1), 19091 (Prkg1)

Available reactivities

Hu (Human), Bov (Bovine), Ms (Mouse), Rt (Rat), Por (Porcine)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Paraffin Sections (P), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Flow Cytometry (F)

Background of CGK1 antibody

Mammals have three different isoforms of cyclic GMP-dependent protein kise (Ialpha, Ibeta, and II). These PRKG isoforms act as key mediators of the nitric oxide/cGMP sigling pathway and are important components of many sigl transduction processes in diverse cell types. This PRKG1 gene on human chromosome 10 encodes the soluble Ialpha and Ibeta isoforms of PRKG by altertive transcript splicing. A separate gene on human chromosome 4, PRKG2, encodes the membrane-bound PRKG isoform II. The PRKG1 proteins play a central role in regulating cardiovascular and neurol functions in addition to relaxing smooth muscle tone, preventing platelet aggregation, and modulating cell growth. This gene is most strongly expressed in all types of smooth muscle, platelets, cerebellar Purkinje cells, hippocampal neurons, and the lateral amygdala. Isoforms Ialpha and Ibeta have identical cGMP-binding and catalytic domains but differ in their leucine/isoleucine zipper and autoinhibitory sequences and therefore differ in their dimerization substrates and kise enzyme activity.

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  2. Highly Validated (3)

16 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CGK1 antibody

  anti-PRKG1 (cGKI) mouse monoclonal antibody, clone OTI9G4 (formerly 9G4)  
Immunohistochemical staining of paraffin-embedded pancreas tissue within the normal limits using anti-PRKG1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA501151, Dilution 1:50) Mouse IgG1 OTI9G4 Purified Hu ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CGK1 antibody

  anti-PRKG1 (cGKI) mouse monoclonal antibody, clone OTI9A4 (formerly 9A4)  
Anti-PRKG1 mouse monoclonal antibody (TA501208) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY PRKG1(RC220986). Mouse IgG2b OTI9A4 Purified Hu F, ICC/IF, WB
0.1 ml / €379.00
  OriGene Technologies, Inc.

TrueMAB

CGK1 antibody

  Rabbit polyclonal antibody to PRKG1 (protein kinase, cGMP-dependent, type I)  
Sample (30 ug of whole cell lysate). A: JC. B: BCL-1. 7.5% SDS PAGE. TA308717 diluted at 1:10000. Rabbit IgG Aff - Purified Ms WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CGK1 antibody

  Rabbit anti-PRKG1 Polyclonal Antibody  
Western blot analysis of extracts of various cell lines, using PRKG1 antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

CGK1 antibody

Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE) Mouse IgG1 2B3 Purified Hu E, P, WB
50 µg / €530.00
  Acris Antibodies GmbH

CGK1 (N-term) antibody

Western blot analysis of PKG expression in 3T3 cell lysate. Rabbit Aff - Purified Bov, Hu, Ms, Rt WB
0.1 mg / €350.00
  Acris Antibodies GmbH

CGK1 (beta isoform) antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. Rabbit Ig Purified Hu, Ms P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

PRKG antibody

IHC Image for AP22885PU-N
Testis, Human: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit Purified Hu, Ms, Por, Rt P, WB
50 µg / €470.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

PRKG1 - human gene knockout kit via CRISPR

PRKG1 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

PRKG1 - human gene knockout kit via CRISPR

PRKG1 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

CGK1 (transcript variant 2)

  Recombinant protein of human protein kinase, cGMP-dependent, type I (PRKG1), transcript variant 2  
CGK1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

Lysates

Catalog No.    

PRKG1 overexpression lysate

PRKG1 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

PRKG1 overexpression lysate

PRKG1 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, PRKG1 (mGFP-tagged)-Human protein kinase, cGMP-dependent, type I (PRKG1), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, PRKG1 (mGFP-tagged)-Human protein kinase, cGMP-dependent, type I (PRKG1), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,520.00
  OriGene Technologies, Inc.

Lenti ORF particles, PRKG1 (Myc-DDK-tagged)-Human protein kinase, cGMP-dependent, type I (PRKG1), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, PRKG1 (Myc-DDK-tagged)-Human protein kinase, cGMP-dependent, type I (PRKG1), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,370.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Prkg1 (Myc-DDK-tagged) - Mouse protein kinase, cGMP-dependent, type I (Prkg1), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, Prkg1 (Myc-DDK-tagged) - Mouse protein kinase, cGMP-dependent, type I (Prkg1), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €1,220.00
  OriGene Technologies, Inc.

16 Item(s)

per page
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