CGK2 antibody

Principal name

CGK2 antibody

Alternative names for CGK2 antibody

PRKG2, PRKGR2, cGKII, cGMP-dependent protein kinase 2, Type II cGMP-dependent protein kinase

SwissProt ID

Q13237 (Human), Q61410 (Mouse), Q64595 (Rat)

Gene ID

5593 (PRKG2)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Can (Canine)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP)

Background of CGK2 antibody

cGKII is thought to play a key role in a diverse set of physiological pathway. cGKII may mediate intestinal secretion of water and electrolytes induced by the E. coli toxin STa and the intestinal peptide guanylin. Edentification of the pathway that mediates intestinal fluid secretion by E. coli STa has potential medical implications because STa causes traveler's diarrhea and about 50% of infant mortality in developing countries. Transfection experiments in human cells disclose that cGKII phosphorylates SOX9 and attenuates SOX9 function by inhibiting its nuclear entry. Impaired differentiation of cultured KMI chondrocytes can be restored by silencing Sox9 by RNA interference. cGKII is postulated to be a molecular switch that couples the cessation of proliferation and the start of hypertrophic chondrocyte differentiation through attenuating SOX9 function.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CGK2 antibody

Western blot analysis of extracts from HUVEC cells, using CGK 2 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CGK2 antibody

Western blot analysis of extracts from 293 cells, treated with anisomycin (25ug/ml, 30mins), using PKG2 (Ab-126) antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CGK2 (C-term) antibody

(LEFT)Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining.  (RIGHT)Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with cGKII antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. Rabbit Ig Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CGK2 antibody

Western blot (WB) analysis of cGKii antibody (Cat.-No.: AP2483PU-N) in extracts from hela cells. Rabbit Aff - Purified Hu, Ms, Rt WB
0.1 mg / €350.00
  Acris Antibodies GmbH

CGK2 antibody

CGK2 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

CGK2 antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with PRKG2 polyclonal antibody ( Cat # PAB3193 ) , which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma. Rabbit Hu E, P
0.4 ml / €390.00
  Abnova Taiwan Corp.

CGK2 antibody

Western blot analysis of extracts from 293 cells, treated with anisomycin 25ug/ml 30', using PKG2 (Ab-126) Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
50 µg / €205.00
  Assay Biotech

CGK2 antibody

Western blot analysis of extracts from 293 cells, treated with anisomycin 25ug/ml 30', using PKG2 (Ab-126) Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €310.00
  Assay Biotech

CGK2 antibody

Western blot analysis of extracts from HuvEc cells, using CGK 2 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
50 µg / €205.00
  Assay Biotech

CGK2 antibody

Western blot analysis of extracts from HuvEc cells, using CGK 2 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €310.00
  Assay Biotech

CGK2 antibody

Western blot analysis of cGK 2 expression in HeLa (A); Hs67 (B) whole cell lysates. Rabbit Aff - Purified Can, Hu WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

CGK2 antibody

Western blot analysis of cGK 2 expression in HeLa (A); Hs67 (B) whole cell lysates. Rabbit Aff - Purified Can, Hu WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

CGK2 antibody

Western blot analysis of cGK 2 expression in HeLa (A); Hs67 (B) whole cell lysates. Rabbit Aff - Purified Can, Hu WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

CGK2 antibody

CGK2 Rabbit 12G8 Aff - Purified Hu, Ms, Rt ICC/IF, WB
0.1 ml / €320.00
  Novus Biologicals Inc.

CGK2 antibody

CGK2 Rabbit IgG Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €360.00
  Novus Biologicals Inc.

CGK2 antibody

CGK2 Rabbit IgG Aff - Purified Hu, Ms, Rt E, WB
50 µg / €290.00
  Novus Biologicals Inc.

CGK2 antibody

Immunohistochemistry-Paraffin: CGK2 Antibody [NBP1-84497] Immunohistochemical staining of human cerebral cortex shows strong nuclear and cytoplasmic positivity in neuronal cells. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

CGK2

CGK2 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

CGK2

CGK2 Human Purified
2 µg / €300.00
  Abnova Taiwan Corp.

CGK2

CGK2 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

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