CGRP / CALCA antibody

Principal name

CGRP / CALCA antibody

Alternative names for CGRP / CALCA antibody

Calcitonin gene-related peptide I, Alpha-type CGRP, CALC1, CGRP-I

SwissProt ID

P01256 (Rat), P06881 (Human), P10286 (Chick), P30880 (Pig), P30881 (Sheep), Q99JA0 (Mouse), Q9MYV1 (Canfa), Q9N0T2 (Horse)

Gene ID

24241 (Calca), 796 (CALCA), 12310

Available reactivities

Hu (Human), Mam (Mammalia), Ms (Mouse), Por (Porcine), Rt (Rat), GP (Guinea Pig), Re (Reptiles), Can (Canine)

Available hosts

Rabbit, Chicken, Guinea Pig, Goat, Mouse, Sheep

Available applications

Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Immunoprecipitation (IP), Radioimmunoassay (R)

Background of CGRP / CALCA antibody

Calcitonin gene-related peptide (CGRP), amylin (AMY), and adrenomedullin (ADM) are structurally related peptides of the same family. They are characterized by six to seven amino acid ring structure linked by a disulfide bridge and an amidated C-terminus. CGRP is a 37 amino acid peptide derived from the alternative splicing, which is tissue specific, of the calcitonin gene and may exist in two forms alpha and beta with similar biological functions. Calcitonin gene-related peptide is widely found in both the central and peripheral (sensory and motor neurons) nervous systems. Structural activity studies have found that following peripheral or intracerebroventricular injections of CGRP, several biological actions have been demonstrated that are mediated by the activation of the CGRP receptor subtypes designated CGRP1 and CGRP2. BIBN4096BS, a potent non-peptide antagonist, competitively antagonizes the effects of CGRP in the rat atrium with a potency of about 10-fold higher than that of CGRP (8-37). BIBN4096BS was much less potent at antagonizing the effects of CGRP, proposed to be mediated by the CGRP2 subtype. An orphan receptor originally described as the calcitonin-receptor- like receptor (CRLR) has been identified as a CGRP receptor. Co-expression with a single transmembrane receptor, termed receptor-activity-modifying protein 1 (RAMP1), is required for this receptor to behave as a CGRP1 receptor.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CGRP / CALCA antibody

CGRP / CALCA Guinea Pig Serum Hu, Ms, Rt C, ICC/IF, P
50 µl / €560.00
  Acris Antibodies GmbH

CGRP / CALCA antibody

  Mouse Anti-Calcitonin Gene Related Peptide (CGRP) Antibody  
Immunostaining of CGRP (red) in cryopreserved DRG neurons grown on coverslips. 40xmag. Green staining is PGP9.5. Yellow staining is the colocalization of CGRP and PGP9.5. Cells were obtained photo was provided courtesy of QBMCellScience. Mouse IgG2a 4901 Aff - Purified Hu, Mam, Rt C, ICC/IF
0.1 ml / €325.00
  OriGene Technologies, Inc.

CGRP / CALCA antibody

  Rabbit polyclonal anti-CALCA (KC) antibody  
Western blot analysis of KC in transfected cells. Rabbit Purified Ms, Rt IP, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CGRP / CALCA antibody

  Rabbit Polyclonal Calcitonin Antibody  
Immunohistochemistry staining of Paraffin Medullary carcinoma of thyroid tissue by Calcitonin antibody (dilution: 1:200 - 1:1000; visualization of staining: Cytoplasmic) Rabbit Purified Hu P
1 ml / €760.00
  OriGene Technologies, Inc.

CGRP / CALCA antibody

  Rabbit anti-CALCA Polyclonal Antibody  
Western blot analysis of extracts of mouse lung, using CALCA antibody. Rabbit IgG Purified Hu, Ms
0.1 mg / €325.00
  OriGene Technologies, Inc.

CGRP / CALCA antibody

  Rabbit Polyclonal Anti-CALCA Antibody  
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using (CALCA Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200) Rabbit IgG Purified Hu E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

CGRP / CALCA antibody

  Rabbit Polyclonal Anti-CALCA Antibody  
CGRP / CALCA Rabbit IgG Purified Hu E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

CGRP / CALCA antibody

CGRP / CALCA Rabbit Serum Can, Ms, Rt C, ICC/IF, P
50 µl / €540.00
  Acris Antibodies GmbH

CGRP / CALCA (Center) antibody

CALCA Antibody (Center) (Cat. #AP50713PU-N)immunohistochemistry analysis in formalin fixed and paraffin embedded human thyroid tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CALCA Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated. Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CGRP / CALCA antibody

Figure 1. Paraffin embedded rat intestine stained with Goat anti Rat CGRP antibody Cat.-No BP022. Goat IgG Purified GP, Ms, Re, Rt C, E, ICC/IF, P
0.1 ml / €330.00
  Acris Antibodies GmbH

CGRP / CALCA antibody

CGRP / CALCA Rabbit Serum Hu, Ms, Rt C, ICC/IF, P
50 µl / €560.00
  Acris Antibodies GmbH

CGRP / CALCA antibody

CGRP / CALCA Guinea Pig Serum Hu, Rt C, P
50 µl / €560.00
  Acris Antibodies GmbH

CGRP / CALCA antibody

Staining with CGRP (Calcitonin Gene Related Peptide) Antibody 24112 Rabbit IgG Serum Hu, Mam, Ms, Por, Rt C, ICC/IF
0.1 ml / €390.00
  ImmunoStar Inc.

CGRP / CALCA antibody

CGRP / CALCA Chicken Purified Rt C
50 µl / €250.00
  Neuromics Antibodies

CGRP / CALCA antibody

CGRP / CALCA Chicken Purified Rt C
0.15 ml / €450.00
  Neuromics Antibodies

CGRP / CALCA antibody

CGRP terminal and fiber staining in rat dorsal horn (spinal cord), cryostat sections, ABC / DAB detection. Rabbit IgG Serum Hu, Rt C, ICC/IF
0.1 ml / €350.00
  Neuromics Antibodies

CRISPR

Catalog No. Species Donor Vector  

CALCA - human gene knockout kit via CRISPR

CALCA - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

CGRP / CALCA

CGRP / CALCA Rat > 95 % > 95% by HPLC Synthetic
50 µg / €210.00
  Acris Antibodies GmbH

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, CALCA (mGFP-tagged) - Human calcitonin-related polypeptide alpha (CALCA), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, CALCA (mGFP-tagged) - Human calcitonin-related polypeptide alpha (CALCA), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, CALCA (mGFP-tagged) - Human calcitonin-related polypeptide alpha (CALCA), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, CALCA (mGFP-tagged) - Human calcitonin-related polypeptide alpha (CALCA), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

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