CGRP / CALCA antibody

Principal name

CGRP / CALCA antibody

Alternative names for CGRP / CALCA antibody

Calcitonin gene-related peptide I, Alpha-type CGRP, CALC1, CGRP-I

SwissProt ID

P01256 (Rat), P06881 (Human), P10286 (Chick), P30880 (Pig), P30881 (Sheep), Q99JA0 (Mouse), Q9MYV1 (Canfa), Q9N0T2 (Horse)

Gene ID

24241 (Calca), 796 (CALCA), 12310

Available reactivities

Hu (Human), Mam (Mammalia), Ms (Mouse), Por (Porcine), Rt (Rat), Re (Reptiles), Can (Canine)

Available hosts

Rabbit, Chicken, Guinea Pig, Goat, Mouse, Sheep

Available applications

Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Radioimmunoassay (R), ELISA (detection) (E(detection)), Immunoprecipitation (IP)

Background of CGRP / CALCA antibody

Calcitonin gene-related peptide (CGRP), amylin (AMY), and adrenomedullin (ADM) are structurally related peptides of the same family. They are characterized by six to seven amino acid ring structure linked by a disulfide bridge and an amidated C-terminus. CGRP is a 37 amino acid peptide derived from the alternative splicing, which is tissue specific, of the calcitonin gene and may exist in two forms alpha and beta with similar biological functions. Calcitonin gene-related peptide is widely found in both the central and peripheral (sensory and motor neurons) nervous systems. Structural activity studies have found that following peripheral or intracerebroventricular injections of CGRP, several biological actions have been demonstrated that are mediated by the activation of the CGRP receptor subtypes designated CGRP1 and CGRP2. BIBN4096BS, a potent non-peptide antagonist, competitively antagonizes the effects of CGRP in the rat atrium with a potency of about 10-fold higher than that of CGRP (8-37). BIBN4096BS was much less potent at antagonizing the effects of CGRP, proposed to be mediated by the CGRP2 subtype. An orphan receptor originally described as the calcitonin-receptor- like receptor (CRLR) has been identified as a CGRP receptor. Co-expression with a single transmembrane receptor, termed receptor-activity-modifying protein 1 (RAMP1), is required for this receptor to behave as a CGRP1 receptor.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CGRP / CALCA antibody

CGRP / CALCA Guinea Pig Serum Hu, Ms, Rt C, ICC/IF, P
50 µl / €540.00
  Acris Antibodies GmbH

CGRP / CALCA antibody

Immunostaining of CGRP (red) in cryopreserved DRG neurons grown on coverslips. 40xmag. Green staining is PGP9.5. Yellow staining is the colocalization of CGRP and PGP9.5. Cells were obtained photo was provided courtesy of QBMCellScience. Mouse IgG2a 4901 Aff - Purified Hu, Mam, Rt C, ICC/IF
0.1 ml / €325.00
  OriGene Technologies, Inc.

CGRP / CALCA antibody

Western blot analysis of KC in transfected cells. Rabbit Purified Ms, Rt IP, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CGRP / CALCA antibody

Immunohistochemistry staining of Paraffin Medullary carcinoma of thyroid tissue by Calcitonin antibody (dilution: 1:200 - 1:1000; visualization of staining: Cytoplasmic) Rabbit Purified Hu P
1 ml / €460.00
  OriGene Technologies, Inc.

CGRP / CALCA antibody

Western blot analysis of extracts of mouse lung, using CALCA antibody. Rabbit IgG Purified Hu, Ms
0.1 mg / €325.00
  OriGene Technologies, Inc.

CGRP / CALCA antibody

CGRP / CALCA Goat Serum Hu R
0.1 ml / €380.00
  Acris Antibodies GmbH

CGRP / CALCA antibody

CGRP / CALCA Goat Serum Hu R
20 µl / €150.00
  Acris Antibodies GmbH

CGRP / CALCA antibody

CGRP / CALCA Rabbit Serum Can, Ms, Rt C, ICC/IF, P
50 µl / €420.00
  Acris Antibodies GmbH

CGRP / CALCA (Center) antibody

CALCA Antibody (Center) (Cat. #AP50713PU-N)immunohistochemistry analysis in formalin fixed and paraffin embedded human thyroid tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CALCA Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated. Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CGRP / CALCA antibody

Figure 1. Paraffin embedded rat intestine stained with Goat anti Rat CGRP antibody Cat.-No BP022. Goat IgG Purified GP, Ms, Re, Rt C, E, ICC/IF, P
0.1 ml / €330.00
  Acris Antibodies GmbH

CGRP / CALCA antibody

CGRP / CALCA Rabbit Serum Hu, Ms, Rt C, ICC/IF, P
50 µl / €540.00
  Acris Antibodies GmbH

CGRP / CALCA antibody

CGRP / CALCA Guinea Pig Serum Hu, Rt C, P
50 µl / €540.00
  Acris Antibodies GmbH

CGRP / CALCA antibody

CGRP / CALCA Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

CGRP / CALCA antibody

Western Blot analysis of CALCA expression in transfected 293T cell line (H00000796-T01) by CALCA MaxPab polyclonal antibody.

Lane 1: CALCA transfected lysate(15.51 KDa).
Lane 2: Non-transfected lysate. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

CGRP / CALCA antibody

Western Blot analysis of CALCA expression in transfected 293T cell line by CALCA monoclonal antibody (M01), clone 4B10.

Lane 1: CALCA transfected lysate(15.5 KDa).
Lane 2: Non-transfected lysate. Mouse IgG2a 4B10 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

CGRP / CALCA antibody

CGRP / CALCA Mouse IgG2a 6H11 3E4 Hu E
1 mg / €1,160.00
  Abnova Taiwan Corp.

CGRP / CALCA antibody

CGRP / CALCA Mouse IgG1 IF2 3G11 Hu E
1 mg / €1,160.00
  Abnova Taiwan Corp.

CGRP / CALCA antibody

CGRP / CALCA Mouse IgG1 3B1 1C10 Hu E
1 mg / €990.00
  Abnova Taiwan Corp.

CGRP / CALCA antibody

CGRP / CALCA Mouse IgG1 CB1 Hu E
1 mg / €990.00
  Abnova Taiwan Corp.

CGRP / CALCA antibody

CGRP / CALCA Rabbit Hu E, IP, R
0.4 mg / €390.00
  Abnova Taiwan Corp.

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