CGRP type 1 receptor / CRLR antibody

Principal name

CGRP type 1 receptor / CRLR antibody

Alternative names for CGRP type 1 receptor / CRLR antibody

CALCRL, CGRPR, Calcitonin receptor-like receptor, Calcitonin gene-related peptide type 1 receptor

SwissProt ID

Q16602 (Human), Q63118 (Rat), Q9R1W5 (Mouse)

Gene ID

10203 (CALCRL)

Available reactivities

Bov (Bovine), Can (Canine), Chk (Chicken), Eq (Equine), GP (Guinea Pig), Gt (Goat), Hst (Hamster), Hu (Human), Mky (Monkey), Ms (Mouse), Por (Porcine), Rb (Rabbit), Rt (Rat), Xen (Xenopus), Ze (Zebrafish), Orang-Utan, Gorilla, African clawed frog, Bt (Bat)

Available hosts

Rabbit, Mouse

Available applications

Paraffin Sections (P), Enzyme Immunoassay (E), Western blot / Immunoblot (WB)

Background of CGRP type 1 receptor / CRLR antibody

Calcitonin receptor-like receptor (CRLR) is an Adrenomedullin Receptor that requires two additional proteins to function: a chaperone protein RAMP (receptor activity modifying protein) and the component protein RCP. The function of CRLR depends on its interaction with RAMP. When coexpressed with RAMP1, CRLR acts as a receptor for calcitonin gene-related peptide (CGRP). In contrast, when CRLR is coexpressed with either RAMP2 or RAMP3, it acts as a receptor for adrenomedullin. Activation of the receptor leads to an increase in intracellular cyclic AMP. CRLR mediates the vasorelaxation of arteries, suggesting a potential role for the receptor in reaction to injury, particularly in the treatment of pulmonary hypertension.
CRLR expression has been reported in brain, lung, blood vessel, liver, and intestinal tract. ESTs have been isolated from B-Cell/lung/testis, bone marrow, embryo, lung, and synovium libraries.

General readings

Eskesen,K., Ideggyogy Sz 60 (11-12), 459-466 (2007)

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  2. Highly Validated (1)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CGRP type 1 receptor / CRLR (N-term) antibody

Anti-CALCRL  / CGRP Receptor antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Aff - Purified Gorilla, Hu, Mky, Ms, Orang-Utan, Rb, Rt P
50 µg / €345.00
  OriGene Technologies, Inc.

CGRP type 1 receptor / CRLR (Cytopl. Dom.) antibody

Anti-CALCRL  / CGRP Receptor antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Aff - Purified Bov, Can, Chk, Eq, GP, Gt, Hst, Hu, Mky, Ms, Por, Rb, Rt, Xen, Ze P
50 µg / €345.00
  OriGene Technologies, Inc.

CGRP type 1 receptor / CRLR antibody

CALCRL polyclonal antibody (A01), Lot # UHK2060109QCS1 Western Blot analysis of CALCRL expression in MCF-7 ( Cat # L046V1 ). Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

CGRP type 1 receptor / CRLR antibody

Human Muscle; WB Suggested Anti-CALCRL Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:12500. Positive Control: Human Muscle; CALCRL antibody - N-terminal region (ARP42260_P050) in Human Muscle cells using Western Blot Rabbit Aff - Purified African clawed frog, Bov, Chk, Hu, Ms, Por, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

CGRP type 1 receptor / CRLR antibody

Western Blot: CALCRL Antibody [NBP1-59073] - This Anti-CALCRL antibody was used in Western Blot of Fetal Muscle tissue lysate at a concentration of 1ug/ml. Rabbit Aff - Purified Hu, Ms, Rt WB
50 µg / €440.00
  Novus Biologicals Inc.

CGRP type 1 receptor / CRLR antibody

Immunohistochemistry-Paraffin: CALCRL Antibody [NBP1-85643] Immunohistochemical staining of human skin shows strong cytoplasmic positivity in epidermal cells. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

CGRP type 1 receptor / CRLR

CGRP type 1 receptor / CRLR Human
10 µg / €540.00
  Abnova Taiwan Corp.

CGRP type 1 receptor / CRLR

CGRP type 1 receptor / CRLR Human Purified
2 µg / €300.00
  Abnova Taiwan Corp.

CGRP type 1 receptor / CRLR

CGRP type 1 receptor / CRLR Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

CGRP type 1 receptor / CRLR

CGRP type 1 receptor / CRLR Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

10 Item(s)

per page
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