CGRP type 1 receptor / CRLR antibody

Principal name

CGRP type 1 receptor / CRLR antibody

Alternative names for CGRP type 1 receptor / CRLR antibody

CALCRL, CGRPR, Calcitonin receptor-like receptor, Calcitonin gene-related peptide type 1 receptor

SwissProt ID

Q16602 (Human), Q63118 (Rat), Q9R1W5 (Mouse)

Gene ID

10203 (CALCRL), 54598 (Calcrl), 25029

Available reactivities

Hu (Human), Bov (Bovine), Chk (Chicken), Ms (Mouse), Por (Porcine), Rt (Rat), African clawed frog, Can (Canine), Eq (Equine), GP (Guinea Pig), Gt (Goat), Hst (Hamster), Mky (Monkey), Rb (Rabbit), Xen (Xenopus), Ze (Zebrafish), Orang-Utan, Gorilla

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of CGRP type 1 receptor / CRLR antibody

Calcitonin receptor-like receptor (CRLR) is an Adrenomedullin Receptor that requires two additional proteins to function: a chaperone protein RAMP (receptor activity modifying protein) and the component protein RCP. The function of CRLR depends on its interaction with RAMP. When coexpressed with RAMP1, CRLR acts as a receptor for calcitonin gene-related peptide (CGRP). In contrast, when CRLR is coexpressed with either RAMP2 or RAMP3, it acts as a receptor for adrenomedullin. Activation of the receptor leads to an increase in intracellular cyclic AMP. CRLR mediates the vasorelaxation of arteries, suggesting a potential role for the receptor in reaction to injury, particularly in the treatment of pulmonary hypertension.
CRLR expression has been reported in brain, lung, blood vessel, liver, and intestinal tract. ESTs have been isolated from B-Cell/lung/testis, bone marrow, embryo, lung, and synovium libraries.

General readings

Eskesen,K., Ideggyogy Sz 60 (11-12), 459-466 (2007)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CGRP type 1 receptor / CRLR (N-term) antibody

  CALCRL / CRLR Rabbit Polyclonal (N-Terminus) Antibody  
Anti-CALCRL  / CGRP Receptor antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Aff - Purified Gorilla, Hu, Mky, Ms, Orang-Utan, Rb, Rt P
50 µg / €400.00
  OriGene Technologies, Inc.

CGRP type 1 receptor / CRLR (Cytopl. Dom.) antibody

  CALCRL / CRLR Rabbit Polyclonal (Cytoplasmic Domain) Antibody  
Anti-CALCRL  / CGRP Receptor antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Aff - Purified Bov, Can, Chk, Eq, GP, Gt, Hst, Hu, Mky, Ms, Por, Rb, Rt, Xen, Ze P
50 µg / €400.00
  OriGene Technologies, Inc.

CGRP type 1 receptor / CRLR antibody

  Rabbit Polyclonal Anti-CALCRL Antibody  
WB Suggested Anti-CALCRL Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 12500; Positive Control: Human Muscle Rabbit IgG Purified Bov, Can, Eq, GP, Gt, Hu, Ms, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

CGRP type 1 receptor / CRLR antibody

  Rabbit Polyclonal Anti-CALCRL Antibody  
Gel: 8%SDS-PAGE, Lysate: 40 ug, Lane: Human lung cancer tissue, Primary antibody: (CALCRL Antibody) at dilution 1/550, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 40 seconds Rabbit IgG Purified Hu E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CRISPR

Catalog No. Species Donor Vector  

CALCRL - human gene knockout kit via CRISPR

CALCRL - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

CALCRL - human gene knockout kit via CRISPR

CALCRL - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

CALCRL - human gene knockout kit via CRISPR

CALCRL - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

CALCRL - human gene knockout kit via CRISPR

CALCRL - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Calcrl - mouse gene knockout kit via CRISPR

Calcrl - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Calcrl - mouse gene knockout kit via CRISPR

Calcrl - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Calcrl - mouse gene knockout kit via CRISPR

Calcrl - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Calcrl - mouse gene knockout kit via CRISPR

Calcrl - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, CALCRL (mGFP-tagged)-Human calcitonin receptor-like (CALCRL), 200 uL, >10^7 TU/mL

Lenti ORF particles, CALCRL (mGFP-tagged)-Human calcitonin receptor-like (CALCRL), 200 uL, >10^7 TU/mL  
200 µl / €1,060.00
  OriGene Technologies, Inc.

Lenti ORF particles, CALCRL (Myc-DDK-tagged)-Human calcitonin receptor-like (CALCRL), 200 uL, >10^7 TU/mL

Lenti ORF particles, CALCRL (Myc-DDK-tagged)-Human calcitonin receptor-like (CALCRL), 200 uL, >10^7 TU/mL  
200 µl / €950.00
  OriGene Technologies, Inc.

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Calcrl (GFP-tagged ORF) - Rat calcitonin receptor-like (Calcrl), 200 uL, >10^7 TU/mL

Lenti ORF particles, Calcrl (GFP-tagged ORF) - Rat calcitonin receptor-like (Calcrl), 200 uL, >10^7 TU/mL  
200 µl / €1,070.00
  OriGene Technologies, Inc.

Lenti ORF particles, Calcrl (Myc-DDK-tagged ORF) - Rat calcitonin receptor-like (Calcrl), 200 uL, >10^7 TU/mL

Lenti ORF particles, Calcrl (Myc-DDK-tagged ORF) - Rat calcitonin receptor-like (Calcrl), 200 uL, >10^7 TU/mL  
200 µl / €958.00
  OriGene Technologies, Inc.

16 Item(s)

per page
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