CHERP antibody

Principal name

CHERP antibody

Alternative names for CHERP antibody

ERPROT 213-21, DAN26, SCAF6, Calcium homeostasis endoplasmic reticulum protein, SR-related CTD-associated factor 6

SwissProt ID

Q8CGZ0 (Mouse), Q8IWX8 (Human)

Gene ID

10523 (CHERP)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Dros (Drosophila), Ze (Zebrafish), African clawed frog, Xen (Xenopus), Eq (Equine), GP (Guinea Pig), Por (Porcine)

Available hosts

Rabbit, Mouse

Available applications

Frozen Sections (C), Enzyme Immunoassay (E), Immunoprecipitation (IP), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), ELISA (detection) (E(detection)), Paraffin Sections (P)

Background of CHERP antibody

The Calcium homoeostasis endoplasmic reticulum protein (CHERP) gene has been recently identified and localized on chromosome 19p13.1. The CHERP has high homology to a SR-related CTD protein, which is known to interact with largest subunit of RNA polymerase II (2). CHERP is an integral endoplasmic reticulum membrane protein is involved in calcium mobilization induced by thrombin. The confocal microscopy revealed that CFERP is associated with Ins(1,4,5)P3 receptor throughout the cytoplasm and perinuclear region in Jurkat T lymphocyte (1). CHERP Anti-sense treatment induced decrease in CHERP caused an impaired increase in free cytoplasmic calcium but calcium influx remains unaffected, with some deficient in endoplasmic reticulum calcium stores (1). In the CHERP depleted Jurkat T lymphocytes the calcium dependent translocation of nuclear factor of activated T cells (NFAT) from cytoplasm to nucleus was also suppressed with significant suppression of cell (1).
CHERP is an endoplasmic integral membrane protein. the CHERP mRNA is expressed ubiquitously in various tissues including lung, brain, heart, pancreas, kidney and skeletal muscle. CHERP is a 883 amino acid protein (100 kDa) with theoretical PI of 9.46. there exist a 5’ Kozak sequence with another inframe start codon that could possible generate a variant with 32 extra amino acids. The CHERP has two transmembrane domains characteristic feature of ion channels with several possible protein protein interaction sites (3). There are several Serine/Threonine phosphorylation sites (PKA, PKC, casein kinase, and glycogen synthese kinase) near the C-terminal end of the protein. Several tyrosine kinase sites are also present out side the serine/threonine kinase domain.

General readings

Laplante,J.M., Biochem. J. 348 PT 1, 189-199 (2000)

20 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CHERP antibody

WB Suggested Anti-CHERP Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 312500; Positive Control: HT1080 cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

CHERP antibody

WB Suggested Anti-CHERP Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 62500; Positive Control: 293T cell lysateCHERP is supported by BioGPS gene expression data to be expressed in HEK293T Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

CHERP Control Peptide

CHERP
0.25 mg / €250.00
  Acris Antibodies GmbH

CHERP antibody

CHERP Rabbit Aff - Purified Hu, Ms, Rt C, E, IP, WB
0.1 mg / €420.00
  Acris Antibodies GmbH

CHERP antibody

CHERP Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

CHERP antibody

Western Blot analysis of CHERP expression in transfected 293T cell line (H00010523-T02) by CHERP MaxPab polyclonal antibody.

Lane 1: CHERP transfected lysate(100.00 KDa).
Lane 2: Non-transfected lysate. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

CHERP antibody

CHERP monoclonal antibody (M01), clone 2H5 Western Blot analysis of CHERP expression in IMR-32 ( Cat # L008V1 ). Mouse IgG2b 2H5 Purified Hu E, WB
50 µg / €370.00
  Abnova Taiwan Corp.

CHERP antibody

CHERP Mouse IgG2b 1A5 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

CHERP antibody

Human HT1080; WB Suggested Anti-CHERP Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:312500. Positive Control: HT1080 cell lysate; CHERP antibody - middle region (ARP40642_P050) in Human HT1080 cells using Western Blot Rabbit Aff - Purified African clawed frog, Bov, Can, Dros, Hu, Ms, Rt, Ze WB
50 µg / €350.00
  AVIVA Systems Biology

CHERP antibody

Human 293T; WB Suggested Anti-CHERP Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:62500. Positive Control: 293T cell lysate. CHERP is supported by BioGPS gene expression data to be expressed in HEK293T.; CHERP antibody - middle region (ARP40643_P050) in Human 293T cells using Western Blot Rabbit Aff - Purified African clawed frog, Bov, Can, Hu, Ms, Rt, Ze WB
50 µg / €350.00
  AVIVA Systems Biology

CHERP antibody

Western blot analysis of CHERP expression in THP1 (A); K562 (B); Raw264.7 (C); H9C2 (D) whole cell lysates. Rabbit Aff - Purified Bov, Hu, Ms, Rt WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

CHERP antibody

Western blot analysis of CHERP expression in THP1 (A); K562 (B); Raw264.7 (C); H9C2 (D) whole cell lysates. Rabbit Aff - Purified Bov, Hu, Ms, Rt WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

CHERP antibody

Western blot analysis of CHERP expression in THP1 (A); K562 (B); Raw264.7 (C); H9C2 (D) whole cell lysates. Rabbit Aff - Purified Bov, Hu, Ms, Rt WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

CHERP antibody

CHERP Rabbit Aff - Purified Bov, Can, Dros, Hu, Ms, Rt, Xen, Ze WB
50 µg / €440.00
  Novus Biologicals Inc.

CHERP antibody

CHERP Rabbit Aff - Purified Bov, Can, Hu, Ms, Rt, Xen, Ze WB
50 µg / €440.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

CHERP

CHERP Human Purified
2 µg / €300.00
  Abnova Taiwan Corp.

CHERP

CHERP Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

CHERP

CHERP Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

CHERP 293T Cell Transient Overexpression Lysate(Denatured)

CHERP 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

CHERP overexpression lysate

CHERP overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

20 Item(s)

per page
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