CHMP2A / BC2 antibody

Principal name

CHMP2A / BC2 antibody

Alternative names for CHMP2A / BC2 antibody

CHMP2, BC-2, Vps2-1, Charged multivesicular body protein 2a, Chromatin-modifying protein 2a, Vacuolar protein-sorting-associated protein 2-1, Putative breast adenocarcinoma marker BC-2

SwissProt ID

O43633 (Human), Q5ZHN1 (Chick), Q9DB34 (Mouse)

Gene ID

27243 (CHMP2A), 4527243 (A0QJ63)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit, Mouse

Available applications

Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Frozen Sections (C), Paraffin Sections (P)

Background of CHMP2A / BC2 antibody

Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and the budding of enveloped viruses (HIV-1 and other lentiviruses). ESCRT-III proteins are believed to mediate the necessary vesicle extrusion and/or membrane fission activities, possibly in conjunction with the AAA ATPase VPS4. Involved in HIV-1 p6- and p9-dependent virus release.

General readings

Lata S., et al. (2008) Science. 321(5894):1354-7.
Agromayor M., et al. (2006) J Biol Chem. 281(32):23083-91.

11 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CHMP2A / BC2 antibody

Western Blot analysis of CHMP2A expression in transfected 293T cell line (H00027243-T03) by CHMP2A MaxPab polyclonal antibody.

Lane 1: CHMP2A transfected lysate(24.42 KDa).
Lane 2: Non-transfected lysate. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

CHMP2A / BC2 antibody

CHMP2A / BC2 Rabbit Serum Hu, Ms, Rt C, P, WB
0.1 ml / €400.00
  Novus Biologicals Inc.

CHMP2A / BC2 antibody

Immunohistochemistry-Paraffin: CHMP2A Antibody [NBP1-91780] Immunohistochemical staining of human urinary bladder shows strong cytoplasmic positivity in urothelium. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

CHMP2A / BC2 antibody

Immunohistochemistry-Paraffin: CHMP2A Antibody [NBP1-91781] Immunohistochemical staining of human stomach shows strong cytoplasmic positivity in glandular cells. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

CHMP2A / BC2 (transcript variant 2)

CHMP2A / BC2 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

CHMP2A / BC2 (1-222, His-tag)

CHMP2A / BC2 Human Purified > 90 % by SDS - PAGE E. coli
0.5 mg / €1,000.00
  Acris Antibodies GmbH

CHMP2A / BC2 (1-222, His-tag)

CHMP2A / BC2 Human Purified > 90 % by SDS - PAGE E. coli
0.1 mg / €370.00
  Acris Antibodies GmbH

CHMP2A / BC2

CHMP2A / BC2 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

CHMP2A / BC2

CHMP2A / BC2 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

CHMP2A / BC2

SDS-Page: CHMP2A Protein [NBP1-30206] - CHMP2A, 27.2 kDa (242aa), confirmed by MALDI-TOF with a purity of 90% by SDS - PAGE
0.1 mg / €440.00
  Novus Biologicals Inc.

Lysates

Catalog No.    

CHMP2A / BC2 Lysate(Denatured)

CHMP2A / BC2 Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

11 Item(s)

per page
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