CHMP2B antibody

Principal name

CHMP2B antibody

Alternative names for CHMP2B antibody

CHMP2.5, CGI-84, hVps2-2, Charged multivesicular body protein 2b, Chromatin-modifying protein 2b, Vacuolar protein-sorting-associated protein 2-2

SwissProt ID

Q3SX42 (Bovin), Q5F3A2 (Chick), Q8BJF9 (Mouse), Q9UQN3 (Human)

Gene ID

25978 (CHMP2B), 6259788 (IPR000873), 68942 (Chmp2b)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Eq (Equine), Por (Porcine), Rb (Rabbit)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Western blot / Immunoblot (WB), Frozen Sections (C)

Background of CHMP2B antibody

Chmp2b is involved in late steps of the endosomal multivesicular bodies (MVB) pathway. Chmp2b recognizes membrane-associated ESCRT-III assemblies and catalyzes their disassembly, possibly in combition with membrane fission. Chmp2b redistributes the ESCRT-III components to the cytoplasm for further rounds of MVB sorting. MVBs contain intralumil vesicles (ILVs) that are generated by invagition and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes ebling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. In conjunction with the ESCRT machinery Chmp2b also appears to function in topologically equivalent membrane fission events, such as the termil stages of cytokinesis. Involved in cytokinesis .

General readings

Rizzu P., et al. (2006) Am J Med Genet B Neuropsychiatr Genet. 141B(8):944-6.
Stuchell-Brereton MD., et al. (2007) Nature. 449(7163):740-4.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CHMP2B antibody

Western blot analysis of extracts of various cell lines, using CHMP2B antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

CHMP2B antibody

CHMP2B Rabbit IgG Purified Bov, Can, Eq, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

CHMP2B antibody

CHMP2B Rabbit Serum Hu C, E, WB
0.2 ml / €400.00
  Acris Antibodies GmbH

CHMP2B antibody

Detection limit for recombinant GST tagged CHMP2B is approximately 1ng/ml as a capture antibody. Mouse IgG1 2H6-1E6 Purified Hu E
0.1 mg / €370.00
  Abnova Taiwan Corp.

CHMP2B antibody

Detection limit for recombinant GST tagged CHMP2B is approximately 0.03ng/ml as a capture antibody. Mouse IgG1 M1 Purified Hu E
0.1 mg / €370.00
  Abnova Taiwan Corp.

CHMP2B antibody

Immunohistochemistry-Paraffin: CHMP2B Antibody [NBP1-84482] - Immunohistochemical staining of human lymph node shows strong cytoplasmic positivity in subsets of lymphoid cells outside reaction centra. Rabbit IgG Aff - Purified Hu ICC/IF, P
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

CHMP2B

CHMP2B Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

CHMP2B (1-213, His-tag)

CHMP2B Human Purified > 90 % E. coli
0.5 mg / €1,000.00
  Acris Antibodies GmbH

CHMP2B (1-213, His-tag)

CHMP2B Human Purified > 90 % E. coli
0.1 mg / €370.00
  Acris Antibodies GmbH

CHMP2B

CHMP2B Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

CHMP2B

CHMP2B Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

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