CHMP4B antibody

Principal name

CHMP4B antibody

Alternative names for CHMP4B antibody

C20orf178, SHAX1, CHMP4b, SNF7-2, hSnf7-2, Vps32-2, hVps32-2, Charged multivesicular body protein 4b, Chromatin-modifying protein 4b, SNF7 homolog associated with Alix 1, Vacuolar protein sorting-associated protein 32-2

SwissProt ID

Q5XGW6 (Xenla), Q5ZHP5 (Chick), Q7ZVC4 (Danre), Q9D8B3 (Mouse), Q9H444 (Human)

Gene ID

128866 (CHMP4B), 75608 (Chmp4b)

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Eq (Equine), GP (Guinea Pig), Ms (Mouse), Por (Porcine), Rb (Rabbit), Rt (Rat), Ze (Zebrafish)

Available hosts

Rabbit

Available applications

Frozen Sections (C), Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of CHMP4B antibody

The charged multivesicular body proteins or chromatin modifying proteins, commonly designated CHMPs, belong to the vacuolar sorting protein family and function as chromatin-modifying proteins. CHMP1-6 are all components of ESCRT (endosomal sorting complex required for transport) I, II or III complexes. These complexes are crucial for sorting endosomal articles into multivesicular bodies (MVBs), and are also required for the formation of these bodies. CHMP4B (charged multivesicular body protein 4b) is a 224 amino acid protein that interacts with Alix, which results in the redistribution of Alix from the cytoplasm to the perinuclear area. Overexpression of CHMP4B induces accumulation of ubiquinated proteins and inhibits degradation of endocytosed EGF. Defects in the gene encoding CHMP4B can cause posterior polar cataract type 3 (CTPP3), a disease characterized by distinct opacity located at the back of the lens resulting in visual impairment and eventual blindness.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CHMP4B antibody

  Rabbit Polyclonal Anti-CHMP4B Antibody  
WB Suggested Anti-CHMP4B Antibody Titration: 0.2-1 ug/ml; Positive Control: Jurkat cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

CHMP4B antibody

  Rabbit Polyclonal Anti-CHMP4B Antibody  
WB Suggested Anti-CHMP4B Antibody Titration: 0.2-1 ug/ml; Positive Control: THP-1 cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

CHMP4B antibody

  Rabbit Polyclonal Anti-CHMP4B Antibody  
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using (CHMP4B Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200) Rabbit IgG Purified Hu, Ms E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

CHMP4B antibody

CHMP4B Rabbit Purified Hu C, E, WB
0.1 mg / €420.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

CHMP4B - human gene knockout kit via CRISPR

CHMP4B - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

CHMP4B - human gene knockout kit via CRISPR

CHMP4B - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

CHMP4B - human gene knockout kit via CRISPR

CHMP4B - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

CHMP4B - human gene knockout kit via CRISPR

CHMP4B - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Chmp4b - mouse gene knockout kit via CRISPR

Chmp4b - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Chmp4b - mouse gene knockout kit via CRISPR

Chmp4b - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Chmp4b - mouse gene knockout kit via CRISPR

Chmp4b - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Chmp4b - mouse gene knockout kit via CRISPR

Chmp4b - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

CHMP4B

  Recombinant protein of human chromatin modifying protein 4B (CHMP4B)  
CHMP4B Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

CHMP4B overexpression lysate

CHMP4B overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, CHMP4B (mGFP-tagged) - Human chromatin modifying protein 4B (CHMP4B), 200 uL, >10^7 TU/mL

Lenti ORF particles, CHMP4B (mGFP-tagged) - Human chromatin modifying protein 4B (CHMP4B), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, CHMP4B (Myc-DDK tagged) - Human chromatin modifying protein 4B (CHMP4B) , 200 uL, >10^7 TU/mL

Lenti ORF particles, CHMP4B (Myc-DDK tagged) - Human chromatin modifying protein 4B (CHMP4B) , 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Chmp4b (GFP-tagged) - Mouse chromatin modifying protein 4B (cDNA clone MGC:19416 IMAGE:3485793), 200 uL, >10^7 TU/mL

Lenti ORF particles, Chmp4b (GFP-tagged) - Mouse chromatin modifying protein 4B (cDNA clone MGC:19416 IMAGE:3485793), 200 uL, >10^7 TU/mL  
200 µl / €790.00
  OriGene Technologies, Inc.

Lenti ORF particles, Chmp4b (GFP-tagged) - Mouse chromatin modifying protein 4B (Chmp4b), 200 uL, >10^7 TU/mL

Lenti ORF particles, Chmp4b (GFP-tagged) - Mouse chromatin modifying protein 4B (Chmp4b), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, Chmp4b (Myc-DDK-tagged) - Mouse chromatin modifying protein 4B (cDNA clone MGC:19416 IMAGE:3485793), 200 uL, >10^7 TU/mL

Lenti ORF particles, Chmp4b (Myc-DDK-tagged) - Mouse chromatin modifying protein 4B (cDNA clone MGC:19416 IMAGE:3485793), 200 uL, >10^7 TU/mL  
200 µl / €700.00
  OriGene Technologies, Inc.

Lenti ORF particles, Chmp4b (Myc-DDK-tagged) - Mouse chromatin modifying protein 4B (Chmp4b), 200 uL, >10^7 TU/mL

Lenti ORF particles, Chmp4b (Myc-DDK-tagged) - Mouse chromatin modifying protein 4B (Chmp4b), 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

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