CHMP4B antibody

Principal name

CHMP4B antibody

Alternative names for CHMP4B antibody

C20orf178, SHAX1, CHMP4b, SNF7-2, hSnf7-2, Vps32-2, hVps32-2, Charged multivesicular body protein 4b, Chromatin-modifying protein 4b, SNF7 homolog associated with Alix 1, Vacuolar protein sorting-associated protein 32-2

SwissProt ID

Q5XGW6 (Xenla), Q5ZHP5 (Chick), Q7ZVC4 (Danre), Q9D8B3 (Mouse), Q9H444 (Human)

Gene ID

128866 (CHMP4B)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit), Ze (Zebrafish)

Available hosts

Rabbit

Available applications

Frozen Sections (C), Paraffin Sections (P), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of CHMP4B antibody

The charged multivesicular body proteins or chromatin modifying proteins, commonly designated CHMPs, belong to the vacuolar sorting protein family and function as chromatin-modifying proteins. CHMP1-6 are all components of ESCRT (endosomal sorting complex required for transport) I, II or III complexes. These complexes are crucial for sorting endosomal articles into multivesicular bodies (MVBs), and are also required for the formation of these bodies. CHMP4B (charged multivesicular body protein 4b) is a 224 amino acid protein that interacts with Alix, which results in the redistribution of Alix from the cytoplasm to the perinuclear area. Overexpression of CHMP4B induces accumulation of ubiquinated proteins and inhibits degradation of endocytosed EGF. Defects in the gene encoding CHMP4B can cause posterior polar cataract type 3 (CTPP3), a disease characterized by distinct opacity located at the back of the lens resulting in visual impairment and eventual blindness.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CHMP4B antibody

WB Suggested Anti-CHMP4B Antibody Titration: 0.2-1 ug/ml; Positive Control: Jurkat cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

CHMP4B antibody

WB Suggested Anti-CHMP4B Antibody Titration: 0.2-1 ug/ml; Positive Control: THP-1 cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

CHMP4B antibody

CHMP4B Rabbit Purified Hu C, E, WB
0.1 mg / €420.00
  Acris Antibodies GmbH

CHMP4B (Center) antibody

Human Jurkat; WB Suggested Anti-CHMP4B Antibody Titration: 0.2-1 ug/ml. Positive Control: Jurkat cell lysate; CHMP4B antibody - middle region (ARP53339_P050) in Human Jurkat cells using Western Blot Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

CHMP4B (Center) antibody

Human THP-1; WB Suggested Anti-CHMP4B Antibody Titration: 0.2-1 ug/ml. Positive Control: THP-1 cell lysate; CHMP4B antibody - middle region (ARP53340_P050) in Human THP-1 cells using Western Blot Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

CHMP4B antibody

CHMP4B Rabbit Serum Hu, Ms, Rt C, P, WB
0.1 ml / €400.00
  Novus Biologicals Inc.

CHMP4B antibody

Western Blot: CHMP4B Antibody [NBP1-56995] - This Anti-CHMP4B antibody was used in Western Blot of Jurkat       tissue lysate at a concentration of 1ug/ml. Rabbit Aff - Purified Hu WB
50 µg / €440.00
  Novus Biologicals Inc.

CHMP4B antibody

Immunohistochemistry-Paraffin: CHMP4B Antibody [NBP1-91782] Immunohistochemical staining of human rectum shows strong granular cytoplasmic positivity in glandular cells. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

CHMP4B

CHMP4B Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

CHMP4B overexpression lysate

CHMP4B overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

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