CHMP6 antibody

Principal name

CHMP6 antibody

Alternative names for CHMP6 antibody

VPS20, Charged multivesicular body protein 6,Chromatin-modifying protein 6, Vacuolar protein sorting-associated protein 20

SwissProt ID

P0C0A3 (Mouse), Q5ZL55 (Chick), Q96FZ7 (Human)

Gene ID

79643 (CHMP6), 208092 (Chmp6)

Available reactivities

Ms (Mouse), Rt (Rat), Hu (Human), Bov (Bovine), Can (Canine), Eq (Equine), GP (Guinea Pig), Por (Porcine)

Available hosts

Sheep, Rabbit

Available applications

Western blot / Immunoblot (WB), Frozen Sections (C), Paraffin Sections (P), Enzyme Immunoassay (E), Immunoprecipitation (IP)

Background of CHMP6 antibody

FUNCTION: Component of the ESCRT-III complex, which is required for multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-III complex is probably involved in the concentration of MVB cargo. In the ESCRT-III complex, it probably serves as an acceptor for ESCRT-II complex on endosomal membranes.; SUBUNIT: Component of the endosomal sorting required for transport complex III (ESCRT-III), at least composed of CHMP1A, CHMP1B, CHMP2A, CHMP2B, CHMP3/VPS24, CHMP4A/SHAX2, CHMP4B/SHAX1, CHMP4C/SHAX3, CHMP5/SNF7DC2 and CHMP6/VPS20. In the complex, it interacts directly with CHMP4A, CHMP4B and CHMP4C. Interacts directly with SNF8, VPS25 and VPS36 components of the ESCRT-II complex.; SUBCELLULAR LOCATION: Intracytoplasmic membrane. Endosome membrane; Lipid-anchor . Note: Localizes to endosomal membranes.

General readings

Im, Y.J., et al. Dev. Cell 17(2):234-243 (2009)
Fu, D., et al. Biosci. Biotechnol. Biochem. 73(3):494-501 (2009)
Kieffer, C., et al. Dev. Cell 15(1):62-73 (2008)
Lamesch, P., et al. Genomics 89(3):307-315 (2007)
Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CHMP6 antibody

WB Suggested Anti-CHMP6 Antibody; Titration: 1.0 ug/ml; Positive Control: HepG2 Whole Cell Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

CHMP6 (N-term) antibody

Western blot analysis in 293 cell line lysates (35ug/lane) using CHMP6 antibody Cat.-No. AP50899PU-N (N-term). This demonstrates the CHMP6 antibody detected the CHMP6 protein (arrow). Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CHMP6 antibody

CHMP6 Sheep Serum Ms, Rt C, P, WB
0.1 ml / €400.00
  Novus Biologicals Inc.

CHMP6 antibody

Immunohistochemistry-Paraffin: CHMP6 Antibody [NBP1-83726] - Immunohistochemical staining of human parathyroid gland shows strong membranous positivity in glandular cells. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

CHMP6 antibody

Immunohistochemistry-Paraffin: CHMP6 Antibody [NBP1-83727] - Immunohistochemical staining of human testis shows distinct cytoplasmic positivity in cells of ductus seminiferus. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

CHMP6 (1-201, His-tag)

CHMP6 Human Purified > 95 % by SDS - PAGE E. coli
0.5 mg / €730.00
  Acris Antibodies GmbH

CHMP6 (1-201, His-tag)

CHMP6 Human Purified > 95 % by SDS - PAGE E. coli
0.1 mg / €300.00
  Acris Antibodies GmbH

CHMP6

CHMP6 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

CHMP6

CHMP6 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

CHMP6 overexpression lysate

CHMP6 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

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