Cholinephosphotransferase 1 antibody

Principal name

Cholinephosphotransferase 1 antibody

Alternative names for Cholinephosphotransferase 1 antibody

AAPT1-like protein, CHPT1, CPT1, MSTP022, Diacylglycerol cholinephosphotransferase 1

SwissProt ID

Q1LZE6 (Bovin), Q4KLV1 (Xenla), Q5ZHQ5 (Chick), Q66H21 (Rat), Q8C025 (Mouse), Q8WUD6 (Human)

Gene ID

56994 (CHPT1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit

Available applications

Flow Cytometry (F), Western blot / Immunoblot (WB), Paraffin Sections (P), Frozen Sections (C), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of Cholinephosphotransferase 1 antibody

CHPT1, also known as AAPT1-like protein and Diacylglycerol cholinephosphotransferase 1, is a 406 amino acid multi-pass membrane protein that is localized to the golgi apparatus. By catalyzing the phosphatidylcholine biosynthesis from CDP-choline, it plays an essential role in the formation and maintenance of vesicular membranes. CHPT1 is most abundant in testis, as well as small intestine, heart, colon, spleen and prostate. Expression of CHPT1 is increased in cancerous breast cells as compared to normal breast cell lines and it has been determined that the CHPT1 gene exhibits mutations within the cancerous cells. Interestingly, exposure to mustard gas significantly decreases CHPT1 gene expression and activity, an event that may play an important role in the development of acute respiratory distress syndrome (ARDS). There are two isoforms of CHPT1 that are produced as a result of alternative splicing events.

General readings

Akech, J., et al. Biochem. Biophys. Res. Commun. 333(1):35-41 (2005)
Ghosh, A., et al. Biochem. Biophys. Res. Commun. 297(4):1043-1048 (2002)
Henneberry, A.L., et al. J. Biol. Chem. 275(38):29808-29815 (2000)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Cholinephosphotransferase 1 (N-term) antibody

Western blot analysis in Hela, HepG2, K562, MDA-MB453 cell line lysates (35ug/lane) using Cholinephosphotransferase 1 antibody Cat.-No. AP50904PU-N (N-term). This demonstrates the CHPT1 antibody detected the CHPT1 protein (arrow). Rabbit Ig Aff - Purified Hu, Ms F, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Cholinephosphotransferase 1

Cholinephosphotransferase 1 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

Cholinephosphotransferase 1

Cholinephosphotransferase 1 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

3 Item(s)

per page
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