Chondromodulin-1 antibody

Principal name

Chondromodulin-1 antibody

Alternative names for Chondromodulin-1 antibody

LECT1, CHMI, Chondromodulin1, Chondromodulin-I, ChM-I, Leukocyte cell-derived chemotaxin 1

SwissProt ID

O70367 (Rat), O75829 (Human), O77770 (Rabit), P17404 (Bovin), P58239 (Danre), Q9PUU8 (Chick), Q9Z1F6 (Mouse)

Gene ID

11061 (LECT1), 81512 (Lect1)

Available reactivities

Hu (Human), Bov (Bovine), Chk (Chicken), Ms (Mouse), Rb (Rabbit), Rt (Rat), Can (Canine), GP (Guinea Pig), Por (Porcine)

Available hosts

Rabbit, Mouse

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Paraffin Sections (P), Immunoprecipitation (IP)

Background of Chondromodulin-1 antibody

LECT1 is a glycosylated transmembrane protein that is cleaved to form a mature, secreted protein. The mature protein promotes chondrocyte growth and inhibits angiogenesis. The mature protein likely plays a role in endochondral bone development by permitting cartilaginous anlagen to be vascularized and replaced by bone. It may be involved also in the broad control of tissue vascularization during development.This gene encodes a glycosylated transmembrane protein that is cleaved to form a mature, secreted protein. The N-terminus of the precursor protein shares characteristics with other surfactant proteins and is sometimes called chondrosurfactant protein although no biological activity has yet been defined for it. The C-terminus of the precursor protein contains a 25 kDa mature protein called leukocyte cell-derived chemotaxin-1 or chondromodulin-1. The mature protein promotes chondrocyte growth and inhibits angiogenesis. This gene is expressed in the avascular zone of prehypertrophic cartilage and its expression decreases during chondrocyte hypertrophy and vascular invasion. The mature protein likely plays a role in endochondral bone development by permitting cartilaginous anlagen to be vascularized and replaced by bone. It may be involved also in the broad control of tissue vascularization during development. Alternative splicing results in multiple transcript variants encoding different isoforms.

General readings

Fujii,M., et al. (2013) J. Orthop. Res. 31 (4), 538-543

13 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Chondromodulin-1 antibody

  Rabbit Polyclonal Anti-LECT1 Antibody  
WB Suggested Anti-LECT1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 1562500; Positive Control: 721_B cell lysate.LECT1 is supported by BioGPS gene expression data to be expressed in 721_B Rabbit IgG Purified Bov, Can, GP, Hu, Ms, Por, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

Chondromodulin-1 (C-term) antibody

Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with LECT1 antibody (C-term) (Cat.#AP12354PU-N), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. Rabbit Ig Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Chondromodulin-1 (214-334, His-tag)

Chondromodulin-1 Human Purified > 90 % by SDS - PAGE E. coli
0.5 mg / €730.00
  Acris Antibodies GmbH

Chondromodulin-1 (214-334, His-tag)

Chondromodulin-1 Human Purified > 90 % by SDS - PAGE E. coli
0.1 mg / €300.00
  Acris Antibodies GmbH

Chondromodulin-1 (214-333, His-tag)

Chondromodulin-1 Human Purified > 85 % by SDS - PAGE E. coli
0.5 mg / €940.00
  Acris Antibodies GmbH

Chondromodulin-1 (214-333, His-tag)

Chondromodulin-1 Human Purified > 85 % by SDS - PAGE E. coli
0.1 mg / €370.00
  Acris Antibodies GmbH

Lysates

Catalog No.    

LECT1 overexpression lysate

LECT1 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, LECT1 (mGFP-tagged) - Human leukocyte cell derived chemotaxin 1 (LECT1), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, LECT1 (mGFP-tagged) - Human leukocyte cell derived chemotaxin 1 (LECT1), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, LECT1 (mGFP-tagged) - Human leukocyte cell derived chemotaxin 1 (LECT1), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, LECT1 (mGFP-tagged) - Human leukocyte cell derived chemotaxin 1 (LECT1), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, LECT1 (Myc-DDK tagged) - Human leukocyte cell derived chemotaxin 1 (LECT1), transcript variant 1 , 200 uL, >10^7 TU/mL

Lenti ORF particles, LECT1 (Myc-DDK tagged) - Human leukocyte cell derived chemotaxin 1 (LECT1), transcript variant 1 , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Lenti ORF particles, LECT1 (Myc-DDK tagged) - Human leukocyte cell derived chemotaxin 1 (LECT1), transcript variant 2 , 200 uL, >10^7 TU/mL

Lenti ORF particles, LECT1 (Myc-DDK tagged) - Human leukocyte cell derived chemotaxin 1 (LECT1), transcript variant 2 , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Lect1 (GFP-tagged ORF) - Rat leukocyte cell derived chemotaxin 1 (Lect1), 200 uL, >10^7 TU/mL

Lenti ORF particles, Lect1 (GFP-tagged ORF) - Rat leukocyte cell derived chemotaxin 1 (Lect1), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, Lect1 (Myc-DDK-tagged ORF) - Rat leukocyte cell derived chemotaxin 1 (Lect1), 200 uL, >10^7 TU/mL

Lenti ORF particles, Lect1 (Myc-DDK-tagged ORF) - Rat leukocyte cell derived chemotaxin 1 (Lect1), 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

13 Item(s)

per page
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