CIC antibody

Principal name

CIC antibody

Alternative names for CIC antibody

Protein capicua homolog, KIAA0306

SwissProt ID

Q924A2 (Mouse), Q96RK0 (Human)

Gene ID

23152 (CIC)

Available reactivities

Hu (Human), Ms (Mouse), Bov (Bovine), Can (Canine), Rt (Rat), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit)

Available hosts

Rabbit, Mouse

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunoprecipitation (IP), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of CIC antibody

CIC, a human homolog of Drosophila capicua, encodes a high mobility group box transcription factor and is fused to a double homeodomain gene DUX4 as a result of a recurrent chromosomal translocation. It is involved in epidermal growth factor receptor (EGFR) signaling, developmental patterning, and cell fate. In humans, CIC may be involved in granule cell lineage, cerebellar development, and medulloblastoma tumorigenesis. Recent evidence indicates that CIC is involved in Spinocerebellar Ataxia Type 1 (SCA-1) where it interacts directly with the product of the SCA-1 gene Ataxin-1.

General readings

Lee,C.J., et al., (2002) Brain Res. Mol. Brain Res. 106 (1-2), 151-156

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CIC (N-term) antibody

CIC antibody (N-term) (Cat. #AP50924PU-N) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the CIC antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. Rabbit Ig Aff - Purified Hu, Ms P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CIC antibody

Western Blot and IP: CIC Antibody - Detection of Human CIC/Capicua by Western Blot and Immunoprecipitation. Affinity purified rabbit anti-CIC antibody used. CIC was  also immunoprecipitated by rabbit anti-CIC antibody. Rabbit Purified Can, Hu, Ms, Rt IP, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CIC antibody

WB Suggested Anti-CIC Antibody Titration: 1.25ug/ml; Positive Control: Jurkat cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CIC antibody

Immunohistochemical staining of human kidney shows moderate nuclear positivity in tubular and glomerular cells.This validation was performed by Protein Atlas and the presentation of data is for informational purposes only. Rabbit IgG Purified Hu E, ICC/IF, P
50 µg / €325.00
  OriGene Technologies, Inc.

CIC antibody

CIC Mouse Hu WB
0.5 mg / €1,400.00
  Abnova Taiwan Corp.

CIC antibody

Detection of Human CIC/Capicua by Western blot of Immunoprecipitates. Samples : Whole cell lysate ( 1 mg for IP, 20% of IP loaded ) from HeLa cells. Antibodies : CIC polyclonal antibody ( Cat # PAB12457 ) at 3 µg /mg lysate. Rabbit Hu, Ms, Rt IP, WB
0.1 ml / €470.00
  Abnova Taiwan Corp.

CIC antibody

Detection of Human CIC/Capicua by Western blot and Immunoprecipitation. Samples : 1 mg for IP, 20% of IP loaded and 293T ( T; 50 µg ) cells. Antibodies : CIC polyclonal antibody ( Cat # PAB12458 ) used for WB at 1 µg /ml ( A and B ) and used for IP at 3 µg /mg lysate. Rabbit Hu, Ms, Rt IP, WB
0.1 ml / €470.00
  Abnova Taiwan Corp.

CIC antibody

Human Lung; CIC antibody - N-terminal region (ARP32498_T100) in Human Lung cells using Immunohistochemistry Rabbit Aff - Purified Bov, Can, Hu, Ms, Rt P, WB
0.1 mg / €310.00
  AVIVA Systems Biology

CIC antibody

Western blot analysis of CIC expression in HEK293T (A); Raw264.7 (B); PC12 (C) whole cell lysates. Rabbit Aff - Purified Hu, Ms, Rt WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

CIC antibody

Western blot analysis of CIC expression in HEK293T (A); Raw264.7 (B); PC12 (C) whole cell lysates. Rabbit Aff - Purified Hu, Ms, Rt WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

CIC antibody

Western blot analysis of CIC expression in HEK293T (A); Raw264.7 (B); PC12 (C) whole cell lysates. Rabbit Aff - Purified Hu, Ms, Rt WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

CIC antibody

WB and IP: CIC Antibody [NB110-59905] - Detection of Human CIC/Capicua by WB of IPs. Whole cell lysate from HeLa cells. Affinity purified rabbit NB110-59905 used for IP at 3  mcg/mg lysate. CIC was also IPed by rabbit anti-CICa antibody. Rabbit Aff - Purified Can, Hu, Ms, Rt IP
0.1 ml / €360.00
  Novus Biologicals Inc.

CIC antibody

CIC Rabbit Aff - Purified Can, Hu, Ms, Rt IP
0.1 ml / €360.00
  Novus Biologicals Inc.

CIC antibody

CIC Rabbit Aff - Purified Can, Hu, Ms, Rt IP
0.1 ml / €390.00
  Novus Biologicals Inc.

CIC antibody

CIC Rabbit Aff - Purified Can, Hu, Ms, Rt IP
0.1 ml / €390.00
  Novus Biologicals Inc.

CIC antibody

CIC Rabbit Aff - Purified Can, Hu, Ms, Rt IP
0.1 ml / €390.00
  Novus Biologicals Inc.

CIC antibody

CIC Rabbit Aff - Purified Can, Hu, Ms, Rt IP
0.1 ml / €390.00
  Novus Biologicals Inc.

CIC antibody

CIC Rabbit Aff - Purified Can, Hu, Ms, Rt IP
25 µl / €140.00
  Novus Biologicals Inc.

CIC antibody

CIC Rabbit Aff - Purified Can, Hu, Ms, Rt IP, WB
0.1 ml / €360.00
  Novus Biologicals Inc.

CIC antibody

CIC Rabbit Aff - Purified Can, Hu, Ms, Rt IP, WB
0.1 ml / €390.00
  Novus Biologicals Inc.

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