CINP antibody

Principal name

CINP antibody

Alternative names for CINP antibody

Cyclin-dependent kinase 2-interacting protein

SwissProt ID

A6H7E2 (Bovin), Q6GM07 (Xenla), Q9BW66 (Human), Q9D0V8 (Mouse)

Gene ID

51550 (CINP)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit, Chicken

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Flow Cytometry (F), Paraffin Sections (P)

Background of CINP antibody

Cell cycle progression is controlled in part by a family of cyclin proteins and cyclin dependent kinases (Cdks). Cdk proteins work in concert with the cyclins to phosphorylate key substrates involved in each phase of cell cycle progression. Specifically, Cdk2 interacts with Cyclins A, B1, B3, D, or E to control cell cycle progression. The Cyclin-dependent kinase 2-interacting protein (CINP) interacts with components of the replication complex and Cdk2 and Cdc7, thereby providing a functional and physical link between Cdk2 and Cdc7 during firing of the origins of replication. However, CINP is phopshorylated by Cdc7, but not by Cdk2. CINP also interacts with ATR-interacting protein and regulates ATR-dependent signaling, resistance to replication stress and G2 checkpoint integrity.

General readings

Grishina I., et al. (2005) Cell Cycle. 4:1120-1126.
Lovejoy C.A., et al. (2009) Proc. Natl. Acad. Sci. U.S.A. 106:19304-19309.

7 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CINP antibody

CINP Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

CINP antibody

CINP Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

CINP (1-212, His-tag)

CINP Human Purified > 95 % E. coli
0.5 mg / €750.00
  Acris Antibodies GmbH

CINP (1-212, His-tag)

CINP Human Purified > 95 % E. coli
0.1 mg / €300.00
  Acris Antibodies GmbH

CINP

CINP Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

CINP

CINP Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

CINP 293T Cell Transient Overexpression Lysate(Denatured)

CINP 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

7 Item(s)

per page
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