CIP2A antibody

Principal name

CIP2A antibody

Alternative names for CIP2A antibody

KIAA1524, CIP2A, Cancerous inhibitor of PP2A, p90 autoantigen

SwissProt ID

Q8TCG1 (Human)

Gene ID

57650 (KIAA1524)

Available reactivities

Hu (Human), Mky (Monkey), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunoprecipitation (IP), Enzyme Immunoassay (E)

Background of CIP2A antibody

Inhibition of protein phosphatase 2A (PP2A) activity has been identified as a prerequisite for the transformation of human cells. The protein, designated Cancerous Inhibitor of PP2A (CIP2A, p90 Autoantigen), interacts directly with the oncogenic transcription factor c-Myc, inhibits PP2A activity toward c-Myc serine 62 (S62), and thereby prevents c-Myc proteolytic degradation. In addition to its function in c-Myc stabilization, p90 Autoantigen promotes anchorage-independent cell growth and in vivo tumor formation. The oncogenic activity of p90 Autoantigen is demonstrated by transformation of human cells by overexpression of p90 Autoantigen. Importantly, p90 Autoantigen is overexpressed in two common human malignancies, head and neck squamous cell carcinoma (HNSCC) and colon cancer.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CIP2A antibody

Detection of CIP2A in HeLa whole cell lysate Mouse IgG2b 2G10 Purified Hu ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CIP2A antibody

Immunohistochemical staining of paraffin-embedded Human lymphoma tissue using anti-KIAA1524 mouse monoclonal antibody.(Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer (pH8.5) at 120 oC for 3 min, TA808416)(1:150) Mouse IgG1 OTI1C11 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CIP2A antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY KIAA1524 (RC219918, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-KIAA1524.(1:2000) Mouse IgG1 OTI4F5 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CIP2A antibody

Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-KIAA1524 mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA808455)(1:150) Mouse IgG1 OTI9E6 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CIP2A antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY KIAA1524 (RC219918, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-KIAA1524.(1:2000) Mouse IgG2b OTI2A1 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CIP2A antibody

CIP2A Mouse Hu WB
0.5 mg / €1,400.00
  Abnova Taiwan Corp.

CIP2A antibody

Western Blot Analysis of KIAA1524 in HeLa whole cell lysate using KIAA1524 monoclonal antibody, clone 2G10 ( Cat #MAB2337 ). Mouse IgG2b 2G10 Hu ICC/IF, WB
0.1 ml / €470.00
  Abnova Taiwan Corp.

CIP2A antibody

CIP2A Rabbit Hu E, WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

CIP2A antibody

Western Blot and  Immunoprecipitation: CIP2A Antibody [NB100-68264] - Detection of Human CIP2A on HeLa whole cell lysate using NB100-68264. CIP2A was also immunoprecipitated by rabbit anti-CIP2A antibody NB100-68263. Rabbit IgG Aff - Purified Hu IP, P, WB
0.1 ml / €440.00
  Novus Biologicals Inc.

CIP2A antibody

Immunohistochemistry: CIP2A Antibody [NB100-74663] - Detection of Human CIP2A by Immunohistochemistry.  Sample: FFPE section of human colon carcinoma. Antibody:  Affinity purified rabbit anti-CIP2A (Cat. No. NB100-74663) used at  a dilution of 1:250. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

CIP2A antibody

CIP2A Mouse IgG2b 2G10 Biotin Hu ICC/IF, WB
0.1 ml / €360.00
  Novus Biologicals Inc.

CIP2A antibody

CIP2A Mouse IgG2b 2G10 DyLight488 Hu ICC/IF, WB
0.1 ml / €390.00
  Novus Biologicals Inc.

CIP2A antibody

CIP2A Mouse IgG2b 2G10 HRP Hu ICC/IF, WB
0.1 ml / €390.00
  Novus Biologicals Inc.

CIP2A antibody

CIP2A Mouse 2G10 Purified Hu, Mky, Ms, Rt ICC/IF, WB
25 µl / €200.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

CIP2A

CIP2A Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

KIAA1524 overexpression lysate

KIAA1524 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

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