CIRBP antibody

Principal name

CIRBP antibody

Alternative names for CIRBP antibody

A18HNRNP, CIRP, Cold-inducible RNA-binding protein, Glycine-rich RNA-binding protein CIRP

SwissProt ID

O93235 (Xenla), P60824 (Mouse), P60825 (Rat), P60826 (Crigr), Q14011 (Human)

Gene ID

1153 (CIRBP), 12696 (Cirbp)

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Chk (Chicken), Ms (Mouse), Rt (Rat), Ze (Zebrafish), African clawed frog, GP (Guinea Pig), Por (Porcine)

Available hosts

Mouse, Rabbit, Goat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Paraffin Sections (P)

Background of CIRBP antibody

CIRBP, also named as A18HNRNP and CIRP, is a cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. CIRBP is also involved in cap-independent translation upon moderate cold-shock. It acts as a translational activator. CIRBP is a suppressive rather stimulatory effect on proliferation. It acts as a translational repressor. CIRBP is an immortalized gene in murine primary cells. CIRBP promotes assembly of stress granules (SGs), when overexpressed. It is a potential proto-oncogenic proteins upon overexpression. Suppression of CIRBP increased the apoptotic cell population of neural stem cells at moderate low temperature.

General readings

1. Zeng Y, Kulkarni P, Inoue T, Getzenberg RH,
Down-regulating cold shock protein genes impairs cancer cell survival and enhances chemosensitivity. Journal of cellular biochemistry 2009 May 107 (1): 179-88. PMID: 19277990

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CIRBP (81-91) antibody

AP21511PU-N CIRBP antibody staining of Mouse Testis lysate at 0.05 µg/ml (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Bov, Can, Hu, Ms, Rt E, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

CIRBP (C-term) antibody

  Goat Anti-CIRBP (aa 161-172) Antibody  
(0.01ug/ml) staining of Mouse Testis lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Bov, Can, Hu, Ms, Rt E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CIRBP antibody

  Rabbit Polyclonal Anti-CIRBP Antibody  
WB Suggested Anti-CIRBP Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1: 312500 Positive Control: A549 Rabbit IgG Purified Bov, Can, GP, Hu, Por, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

CIRBP antibody

  Rabbit Polyclonal Anti-CIRBP Antibody  
WB Suggested Anti-CIRBP Antibody Titration: 0.2-1 ug/ml; Positive Control: HepG2 cell lysate Rabbit IgG Purified Bov, Can, GP, Hu, Ms, Por, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

CIRBP (C-term) antibody

CIRBP Antibody (C-term) (Cat. #AP50926PU-N) IHC analysis in formalin fixed and paraffin embedded human lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the CIRBP Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. Rabbit Ig Aff - Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

CIRBP (transcript variant 1)

  Recombinant protein of human cold inducible RNA binding protein (CIRBP), transcript variant 1  
CIRBP Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

CIRBP (1-172, His-tag)

Recombinant human CIRBP, 1-172 aa, His-tagged Human Purified > 95 % by SDS-PAGE E. coli
0.5 mg / €750.00
  Acris Antibodies GmbH

CIRBP (1-172, His-tag)

Recombinant human CIRBP, 1-172 aa, His-tagged Human Purified > 95 % by SDS-PAGE E. coli
0.1 mg / €300.00
  Acris Antibodies GmbH

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Cirbp (GFP-tagged) - Mouse cold inducible RNA binding protein (Cirbp), 200 uL, >10^7 TU/mL

Lenti ORF particles, Cirbp (GFP-tagged) - Mouse cold inducible RNA binding protein (Cirbp), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, Cirbp (Myc-DDK-tagged) - Mouse cold inducible RNA binding protein (Cirbp), 200 uL, >10^7 TU/mL

Lenti ORF particles, Cirbp (Myc-DDK-tagged) - Mouse cold inducible RNA binding protein (Cirbp), 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

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