CIS1 antibody

Principal name

CIS1 antibody

Alternative names for CIS1 antibody

CIS-1, CISH, G18, Cytokine-inducible SH2-containing protein, Suppressor of cytokine signaling

SwissProt ID

O70512 (Rat), Q2HJ53 (Bovin), Q62225 (Mouse), Q9NSE2 (Human), Q9PW70 (Chick)

Gene ID

1154 (CISH), 12700 (Cish)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Por (Porcine), Bov (Bovine), Can (Canine), Eq (Equine), Rb (Rabbit)

Available hosts

Mouse, Rabbit

Available applications

ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Frozen Sections (C), Enzyme Immunoassay (E), Immunoprecipitation (IP), Paraffin Sections (P), Dot blot (Dot)

Background of CIS1 antibody

The protein encoded by this gene contains a SH2 domain and a SOCS box domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by IL2, IL3, GM-CSF and EPO in hematopoietic cells. Proteasome-mediated degradation of this protein has been shown to be involved in the inactivation of the erythropoietin receptor. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]. Transcript Variant: This variant (2) lacks a segment in the 5' UTR and coding region compared to variant 1. The translation begins at an in-frame upstream start codon, and results in an isoform (2) with a different N-terminus, as compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

General readings

1. Hu, G., Zhou, R., Liu, J., Gong, A.-Y., Eischeid, A. N., Dittman, J. W., Chen, X.-M. MicroRNA-98 and
let-7 confer cholangiocyte expression of cytokine-inducible Src homology 2-containing protein in
response to microbial challenge. J. Immun. 183: 1617-1624, 2009.
2. Khor, C. C., Vannberg, F. O., Chapman, S. J., Guo, H., Wong, S. H., Walley, A. J., Vukcevic, D.,
Rautanen, A., Mills, T. C., Chang, K.-C., Kam, K.-M., Crampin, A. C., and 23 others. CISH and
susceptibility to infectious diseases. New Eng. J. Med. 362: 2092-2101, 2010.
3. Uchida, K., Yoshimura, A., Inazawa, J., Yanagisawa, K., Osada, H., Masuda, A., Saito, T., Takahashi,
T., Miyajima, A., Takahashi, T. Molecular cloning of CISH, chromosome assignment to 3p21.3, and
analysis of expression in fetal and adult tissues. Cytogenet. Cell Genet. 78: 209-212, 1997

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CIS1 antibody

WB Suggested Anti-Cish Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 62500; Positive Control: Mouse Heart Rabbit IgG Purified Bov, Can, Eq, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

CIS1 antibody

Immunofluorescence of purified MaxPab antibody to CISH on HeLa cell. [antibody concentration 10 ug/ml] Mouse Purified Hu E(detection), ICC/IF, WB
50 µg / €370.00
  Abnova Taiwan Corp.

CIS1 antibody

Western Blot analysis of CISH expression in transfected 293T cell line (H00001154-T01) by CISH MaxPab polyclonal antibody.

Lane 1: CISH transfected lysate(28.70 KDa).
Lane 2: Non-transfected lysate. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

CIS1 antibody

The tissue lysate derived from mouse kidney was immunoprobed by CISH polyclonal antibody ( Cat # PAB12758 ) at 1 : 500. An immunoreactive band is observed around ~ 28kDa. Rabbit Hu, Ms, Rt C, E, IP, WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

CIS1 (N-term) antibody

Mouse Heart; WB Suggested Anti-Cish Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:62500. Positive Control: Mouse Heart; Cish antibody - N-terminal region (ARP52798_P050) in Mouse Heart cells using Western Blot Rabbit Aff - Purified Hu, Ms WB
50 µg / €350.00
  AVIVA Systems Biology

CIS1 antibody

CIS1 Rabbit IgG Aff - Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 mg / €290.00
  Boster Immunoleader

CIS1 antibody

Western blot analysis of G18 expression in MCF7 (A); mouse brain (B); PC12 (C) whole cell lysates. Rabbit Aff - Purified Hu, Ms, Por, Rt WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

CIS1 antibody

Western blot analysis of G18 expression in MCF7 (A); mouse brain (B); PC12 (C) whole cell lysates. Rabbit Aff - Purified Hu, Ms, Por, Rt WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

CIS1 antibody

Western blot analysis of G18 expression in MCF7 (A); mouse brain (B); PC12 (C) whole cell lysates. Rabbit Aff - Purified Hu, Ms, Por, Rt WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

CIS1 antibody

Immunohistochemistry: CISH Antibody [NBP1-30943] - Immunohistochemical analysis of paraffin-embedded Lung CA, using CISH antibody at 1:100 dilution. Rabbit IgG Hu Dot, ICC/IF, P, WB
0.1 mg / €420.00
  Novus Biologicals Inc.

CIS1 antibody

CIS1 Rabbit Aff - Purified Hu, Ms WB
50 µg / €440.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

CIS1

CIS1 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

CIS1

CIS1 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

CIS1

CIS1 Human Purified
10 µg / €380.00
  Abnova Taiwan Corp.

CIS1

CIS1 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

CIS1

CIS1 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

CIS1

CIS1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

CIS1

CIS1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

CISH 293T Cell Transient Overexpression Lysate(Denatured)

CISH 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

CISH overexpression lysate

CISH overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

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